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Giovanni Tonon
Giovanni Tonon
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Somatic mutations affect key pathways in lung adenocarcinoma
L Ding, G Getz, DA Wheeler, ER Mardis, MD McLellan, K Cibulskis, ...
Nature 455 (7216), 1069-1075, 2008
31482008
Pancreatic cancers require autophagy for tumor growth
S Yang, X Wang, G Contino, M Liesa, E Sahin, H Ying, A Bause, Y Li, ...
Genes & development 25 (7), 717-729, 2011
16502011
Telomere dysfunction induces metabolic and mitochondrial compromise
E Sahin, S Colla, M Liesa, J Moslehi, FL Müller, M Guo, M Cooper, ...
Nature 470 (7334), 359-365, 2011
14302011
Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets
T Hideshima, C Mitsiades, G Tonon, PG Richardson, KC Anderson
Nature Reviews Cancer 7 (8), 585-598, 2007
11972007
Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer
G Van Haaften, GL Dalgliesh, H Davies, L Chen, G Bignell, C Greenman, ...
Nature genetics 41 (5), 521-523, 2009
9372009
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation
H Zheng, H Ying, H Yan, AC Kimmelman, DJ Hiller, AJ Chen, SR Perry, ...
Nature 455 (7216), 1129-1133, 2008
8782008
t (11; 19)(q21; p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway
G Tonon, S Modi, L Wu, A Kubo, AB Coxon, T Komiya, K O'Neil, K Stover, ...
Nature genetics 33 (2), 208-213, 2003
6322003
High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients
DR Carrasco, G Tonon, Y Huang, Y Zhang, R Sinha, B Feng, JP Stewart, ...
Cancer cell 9 (4), 313-325, 2006
5292006
The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis
DR Carrasco, K Sukhdeo, M Protopopova, R Sinha, M Enos, DE Carrasco, ...
Cancer cell 11 (4), 349-360, 2007
5012007
High-resolution genomic profiles of human lung cancer
G Tonon, KK Wong, G Maulik, C Brennan, B Feng, Y Zhang, DB Khatry, ...
Proceedings of the National Academy of Sciences 102 (27), 9625-9630, 2005
4752005
Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia
P Ntziachristos, A Tsirigos, GG Welstead, T Trimarchi, S Bakogianni, L Xu, ...
Nature 514 (7523), 513-517, 2014
3892014
Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation
C Toffalori, L Zito, V Gambacorta, M Riba, G Oliveira, G Bucci, M Barcella, ...
Nature medicine 25 (4), 603-611, 2019
3552019
Karyotypic complexity of the NCI-60 drug-screening panel
AV Roschke, G Tonon, KS Gehlhaus, N McTyre, KJ Bussey, S Lababidi, ...
Cancer research 63 (24), 8634-8647, 2003
3432003
Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers
F Cottini, T Hideshima, C Xu, M Sattler, M Dori, L Agnelli, E Ten Hacken, ...
Nature medicine 20 (6), 599-606, 2014
3272014
K-ras activation generates an inflammatory response in lung tumors
H Ji, AM Houghton, TJ Mariani, S Perera, CB Kim, R Padera, G Tonon, ...
Oncogene 25 (14), 2105-2112, 2006
3112006
The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma
K Podar, G Tonon, M Sattler, YT Tai, S LeGouill, H Yasui, K Ishitsuka, ...
Proceedings of the National Academy of Sciences 103 (51), 19478-19483, 2006
2592006
Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression
A Calcinotto, A Brevi, M Chesi, R Ferrarese, L Garcia Perez, M Grioni, ...
Nature communications 9 (1), 4832, 2018
2012018
Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel
KJ Bussey, K Chin, S Lababidi, M Reimers, WC Reinhold, WL Kuo, ...
Molecular cancer therapeutics 5 (4), 853-867, 2006
1972006
p63 Sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling
EM Memmi, AG Sanarico, A Giacobbe, A Peschiaroli, V Frezza, ...
Proceedings of the National Academy of Sciences 112 (11), 3499-3504, 2015
1882015
Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma
H Zheng, H Ying, H Yan, AC Kimmelman, DJ Hiller, AJ Chen, SR Perry, ...
Cold Spring Harbor symposia on quantitative biology 73, 427-437, 2008
1532008
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