Somatic mutations affect key pathways in lung adenocarcinoma L Ding, G Getz, DA Wheeler, ER Mardis, MD McLellan, K Cibulskis, ... Nature 455 (7216), 1069-1075, 2008 | 3148 | 2008 |
Pancreatic cancers require autophagy for tumor growth S Yang, X Wang, G Contino, M Liesa, E Sahin, H Ying, A Bause, Y Li, ... Genes & development 25 (7), 717-729, 2011 | 1650 | 2011 |
Telomere dysfunction induces metabolic and mitochondrial compromise E Sahin, S Colla, M Liesa, J Moslehi, FL Müller, M Guo, M Cooper, ... Nature 470 (7334), 359-365, 2011 | 1430 | 2011 |
Understanding multiple myeloma pathogenesis in the bone marrow to identify new therapeutic targets T Hideshima, C Mitsiades, G Tonon, PG Richardson, KC Anderson Nature Reviews Cancer 7 (8), 585-598, 2007 | 1197 | 2007 |
Somatic mutations of the histone H3K27 demethylase gene UTX in human cancer G Van Haaften, GL Dalgliesh, H Davies, L Chen, G Bignell, C Greenman, ... Nature genetics 41 (5), 521-523, 2009 | 937 | 2009 |
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation H Zheng, H Ying, H Yan, AC Kimmelman, DJ Hiller, AJ Chen, SR Perry, ... Nature 455 (7216), 1129-1133, 2008 | 878 | 2008 |
t (11; 19)(q21; p13) translocation in mucoepidermoid carcinoma creates a novel fusion product that disrupts a Notch signaling pathway G Tonon, S Modi, L Wu, A Kubo, AB Coxon, T Komiya, K O'Neil, K Stover, ... Nature genetics 33 (2), 208-213, 2003 | 632 | 2003 |
High-resolution genomic profiles define distinct clinico-pathogenetic subgroups of multiple myeloma patients DR Carrasco, G Tonon, Y Huang, Y Zhang, R Sinha, B Feng, JP Stewart, ... Cancer cell 9 (4), 313-325, 2006 | 529 | 2006 |
The differentiation and stress response factor XBP-1 drives multiple myeloma pathogenesis DR Carrasco, K Sukhdeo, M Protopopova, R Sinha, M Enos, DE Carrasco, ... Cancer cell 11 (4), 349-360, 2007 | 501 | 2007 |
High-resolution genomic profiles of human lung cancer G Tonon, KK Wong, G Maulik, C Brennan, B Feng, Y Zhang, DB Khatry, ... Proceedings of the National Academy of Sciences 102 (27), 9625-9630, 2005 | 475 | 2005 |
Contrasting roles of histone 3 lysine 27 demethylases in acute lymphoblastic leukaemia P Ntziachristos, A Tsirigos, GG Welstead, T Trimarchi, S Bakogianni, L Xu, ... Nature 514 (7523), 513-517, 2014 | 389 | 2014 |
Immune signature drives leukemia escape and relapse after hematopoietic cell transplantation C Toffalori, L Zito, V Gambacorta, M Riba, G Oliveira, G Bucci, M Barcella, ... Nature medicine 25 (4), 603-611, 2019 | 355 | 2019 |
Karyotypic complexity of the NCI-60 drug-screening panel AV Roschke, G Tonon, KS Gehlhaus, N McTyre, KJ Bussey, S Lababidi, ... Cancer research 63 (24), 8634-8647, 2003 | 343 | 2003 |
Rescue of Hippo coactivator YAP1 triggers DNA damage–induced apoptosis in hematological cancers F Cottini, T Hideshima, C Xu, M Sattler, M Dori, L Agnelli, E Ten Hacken, ... Nature medicine 20 (6), 599-606, 2014 | 327 | 2014 |
K-ras activation generates an inflammatory response in lung tumors H Ji, AM Houghton, TJ Mariani, S Perera, CB Kim, R Padera, G Tonon, ... Oncogene 25 (14), 2105-2112, 2006 | 311 | 2006 |
The small-molecule VEGF receptor inhibitor pazopanib (GW786034B) targets both tumor and endothelial cells in multiple myeloma K Podar, G Tonon, M Sattler, YT Tai, S LeGouill, H Yasui, K Ishitsuka, ... Proceedings of the National Academy of Sciences 103 (51), 19478-19483, 2006 | 259 | 2006 |
Microbiota-driven interleukin-17-producing cells and eosinophils synergize to accelerate multiple myeloma progression A Calcinotto, A Brevi, M Chesi, R Ferrarese, L Garcia Perez, M Grioni, ... Nature communications 9 (1), 4832, 2018 | 201 | 2018 |
Integrating data on DNA copy number with gene expression levels and drug sensitivities in the NCI-60 cell line panel KJ Bussey, K Chin, S Lababidi, M Reimers, WC Reinhold, WL Kuo, ... Molecular cancer therapeutics 5 (4), 853-867, 2006 | 197 | 2006 |
p63 Sustains self-renewal of mammary cancer stem cells through regulation of Sonic Hedgehog signaling EM Memmi, AG Sanarico, A Giacobbe, A Peschiaroli, V Frezza, ... Proceedings of the National Academy of Sciences 112 (11), 3499-3504, 2015 | 188 | 2015 |
Pten and p53 converge on c-Myc to control differentiation, self-renewal, and transformation of normal and neoplastic stem cells in glioblastoma H Zheng, H Ying, H Yan, AC Kimmelman, DJ Hiller, AJ Chen, SR Perry, ... Cold Spring Harbor symposia on quantitative biology 73, 427-437, 2008 | 153 | 2008 |