Deniz Dalkara

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Jose Alain SahelSorbonne Université/ University of Pittsburgh School of MedicineVerifisert e-postadresse på inserm.fr
John Gerard FLANNERYProfessor, University of California, BerkeleyVerifisert e-postadresse på berkeley.edu
David SchafferProfessor of Chemical and Biomolecular Engineering, Bioengineering, and Neuroscience, UC BerkeleyVerifisert e-postadresse på berkeley.edu
Olivier MarreInstitut de la Vision, INSERM, ParisVerifisert e-postadresse på inserm.fr
James T. KoerberPrincipal Scientist, Dept. of Antibody Engineering, GenentechVerifisert e-postadresse på gene.com
Sandrine JolyResearch Assistant, InselSpital, University of Bern, SwitzerlandVerifisert e-postadresse på insel.ch
Emilie MacéUniversity Medical Center GoettingenVerifisert e-postadresse på med.uni-goettingen.de
Alexandre MourotINSERM/ CNRS / ESPCIVerifisert e-postadresse på inserm.fr
Dirk TraunerUniversity of PennsylvaniaVerifisert e-postadresse på upenn.edu
Noémie JordiPhD student, Brain Research Institute, ETH and University of ZürichVerifisert e-postadresse på hifo.uzh.ch
Cécile FortunyUC BerkeleyVerifisert e-postadresse på berkeley.edu
Xavier NicolCNRS, Institut de la VisionVerifisert e-postadresse på inserm.fr
Kenneth P. GreenbergUNITYVerifisert e-postadresse på berkeley.edu
Richard T LibbyUniversity of RochesterVerifisert e-postadresse på urmc.rochester.edu
Daniel StoneSr Staff Scientist, Fred Hutchinson Cancer CenterVerifisert e-postadresse på fredhutch.org
Elise OrhanPhD, Institut de la VisionVerifisert e-postadresse på inserm.fr
Mandeep S. Singh, MD PhDAndreas C. Dracopoulos Professor of Ophthalmology, Wilmer Eye Institute, Johns HopkinsVerifisert e-postadresse på jhmi.edu
Erwan BezardUniversity of BordeauxVerifisert e-postadresse på u-bordeaux.fr
Benjamin DEHAYInstitute of Neurodegnerative DiseasesVerifisert e-postadresse på u-bordeaux.fr
Jean-Serge RemyDirector, Laboratory CAMB UMR7199, University of Strasbourg, CNRSVerifisert e-postadresse på unistra.fr

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Deniz Dalkara

1 INSERM, U968, Paris, F-75012, France; 2 Sorbonne Universités, UPMC Univ Paris 06, UMR_S 968

Verifisert e-postadresse på inserm.fr

Gene therapy Retina Optogenetics Viral gene delivery AAV


Tittel Sorter etter sitater Sorter etter år Sorter etter tittel	Sitert av Sitert av	År
In vivo–directed evolution of a new adeno-associated virus for therapeutic outer retinal gene delivery from the vitreous D Dalkara, LC Byrne, RR Klimczak, M Visel, L Yin, WH Merigan, ... Science translational medicine 5 (189), 189ra76-189ra76, 2013	816	2013
Partial recovery of visual function in a blind patient after optogenetic therapy JA Sahel, E Boulanger-Scemama, C Pagot, A Arleo, F Galluppi, JN Martel, ... Nature medicine 27 (7), 1223-1229, 2021	585	2021
Rod-derived cone viability factor promotes cone survival by stimulating aerobic glycolysis N Aït-Ali, R Fridlich, G Millet-Puel, E Clérin, F Delalande, C Jaillard, ... Cell 161 (4), 817-832, 2015	410	2015
Inner limiting membrane barriers to AAV-mediated retinal transduction from the vitreous D Dalkara, KD Kolstad, N Caporale, M Visel, RR Klimczak, DV Schaffer, ... Molecular Therapy 17 (12), 2096-2102, 2009	380	2009
Emerging therapies for inherited retinal degeneration HPN Scholl, RW Strauss, MS Singh, D Dalkara, B Roska, S Picaud, ... Science translational medicine 8 (368), 368rv6-368rv6, 2016	249	2016
A novel adeno-associated viral variant for efficient and selective intravitreal transduction of rat Müller cells RR Klimczak, JT Koerber, D Dalkara, JG Flannery, DV Schaffer PloS one 4 (10), e7467, 2009	242	2009
Intravitreal injection of AAV2 transduces macaque inner retina L Yin, K Greenberg, JJ Hunter, D Dalkara, KD Kolstad, BD Masella, ... Investigative ophthalmology & visual science 52 (5), 2775-2783, 2011	221	2011
Targeting channelrhodopsin-2 to ON-bipolar cells with vitreally administered AAV restores ON and OFF visual responses in blind mice E Macé, R Caplette, O Marre, A Sengupta, A Chaffiol, P Barbe, ... Molecular Therapy 23 (1), 7-16, 2015	220	2015
Molecular evolution of adeno-associated virus for enhanced glial gene delivery JT Koerber, R Klimczak, JH Jang, D Dalkara, JG Flannery, DV Schaffer Molecular Therapy 17 (12), 2088-2095, 2009	219	2009
LiGluR restores visual responses in rodent models of inherited blindness N Caporale, KD Kolstad, T Lee, I Tochitsky, D Dalkara, D Trauner, ... Molecular therapy 19 (7), 1212-1219, 2011	203	2011
Rapid optical control of nociception with an ion-channel photoswitch A Mourot, T Fehrentz, Y Le Feuvre, CM Smith, C Herold, D Dalkara, ... Nature methods 9 (4), 396-402, 2012	199	2012
Viral-mediated RdCVF and RdCVFL expression protects cone and rod photoreceptors in retinal degeneration LC Byrne, D Dalkara, G Luna, SK Fisher, E Clérin, JA Sahel, T Léveillard, ... The Journal of clinical investigation 125 (1), 105-116, 2015	198	2015
Red‐shifted channelrhodopsin stimulation restores light responses in blind mice, macaque retina, and human retina A Sengupta, A Chaffiol, E Macé, R Caplette, M Desrosiers, M Lampič, ... EMBO molecular medicine 8 (11), 1248-1264, 2016	190	2016
Let there be light: gene and cell therapy for blindness D Dalkara, O Goureau, K Marazova, JA Sahel Human gene therapy 27 (2), 134-147, 2016	159	2016
A new promoter allows optogenetic vision restoration with enhanced sensitivity in macaque retina A Chaffiol, R Caplette, C Jaillard, E Brazhnikova, M Desrosiers, E Dubus, ... Molecular Therapy 25 (11), 2546-2560, 2017	157	2017
Long-distance axonal regeneration induced by CNTF gene transfer is impaired by axonal misguidance in the injured adult optic nerve V Pernet, S Joly, D Dalkara, N Jordi, O Schwarz, F Christ, DV Schaffer, ... Neurobiology of disease 51, 202-213, 2013	152	2013
Misguidance and modulation of axonal regeneration by Stat3 and Rho/ROCK signaling in the transparent optic nerve V Pernet, S Joly, N Jordi, D Dalkara, A Guzik-Kornacka, JG Flannery, ... Cell death & disease 4 (7), e734-e734, 2013	136	2013
Vertebrate cone opsins enable sustained and highly sensitive rapid control of Gi/o signaling in anxiety circuitry OA Masseck, K Spoida, D Dalkara, T Maejima, JM Rubelowski, ... Neuron 81 (6), 1263-1273, 2014	135	2014
AAV mediated GDNF secretion from retinal glia slows down retinal degeneration in a rat model of retinitis pigmentosa D Dalkara, KD Kolstad, KI Guerin, NV Hoffmann, M Visel, RR Klimczak, ... Molecular Therapy 19 (9), 1602-1608, 2011	132	2011
Early and late stage gene therapy interventions for inherited retinal degenerations C Botto, M Rucli, MD Tekinsoy, J Pulman, JA Sahel, D Dalkara Progress in Retinal and Eye Research 86, 100975, 2022	128	2022

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