| Synovial tissue macrophages: a sensitive biomarker for response to treatment in patients with rheumatoid arthritis JJ Haringman, DM Gerlag, AH Zwinderman, TJM Smeets, MC Kraan, ... Annals of the rheumatic diseases 64 (6), 834-838, 2005 | 552 | 2005 |
| Asymptomatic synovitis precedes clinically manifest arthritis MC Kraan, H Versendaal, M Jonker, B Bresnihan, WJ Post, BA 't Hart, ... Arthritis & Rheumatism: Official Journal of the American College of …, 1998 | 401 | 1998 |
| The presence of citrullinated proteins is not specific for rheumatoid synovial tissue ER Vossenaar, TJM Smeets, MC Kraan, JM Raats, WJ Van Venrooij, ... Arthritis & Rheumatism 50 (11), 3485-3494, 2004 | 364 | 2004 |
| Rheumatoid arthritis is a heterogeneous disease: evidence for differences in the activation of the STAT‐1 pathway between rheumatoid tissues TCTM van der Pouw Kraan, FA van Gaalen, PV Kasperkovitz, NL Verbeet, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2003 | 311 | 2003 |
| Chemokine blockade and chronic inflammatory disease: proof of concept in patients with rheumatoid arthritis JJ Haringman, MC Kraan, TJM Smeets, KH Zwinderman, PP Tak Annals of the rheumatic diseases 62 (8), 715-721, 2003 | 289 | 2003 |
| Tumor necrosis factor α blockade reduces the synovial cell infiltrate early after initiation of treatment, but apparently not by induction of apoptosis in synovial tissue TJM Smeets, MC Kraan, ME van Loon, PP Tak Arthritis & Rheumatism: Official Journal of the American College of …, 2003 | 287 | 2003 |
| Modulation of inflammation and metalloproteinase expression in synovial tissue by leflunomide and methotrexate in patients with active rheumatoid arthritis: findings in a … MC Kraan, RJ Reece, EC Barg, TJM Smeets, J Farnell, R Rosenburg, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2000 | 272 | 2000 |
| Cell‐derived microparticles in synovial fluid from inflamed arthritic joints support coagulation exclusively via a factor VII–dependent mechanism RJ Berckmans, R Nieuwland, PP Tak, AN Böing, FP Romijn, MC Kraan, ... Arthritis & Rheumatism: Official Journal of the American College of …, 2002 | 261 | 2002 |
| Osteoprotegerin expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthropathies and osteoarthritis and normal controls DR Haynes, E Barg, TN Crotti, C Holding, H Weedon, GJ Atkins, ... Rheumatology 42 (1), 123-134, 2003 | 243 | 2003 |
| Receptor activator NF-κB ligand (RANKL) expression in synovial tissue from patients with rheumatoid arthritis, spondyloarthropathy, osteoarthritis, and from normal patients … TN Crotti, MD Smith, H Weedon, MJ Ahern, DM Findlay, M Kraan, PP Tak, ... Annals of the rheumatic diseases 61 (12), 1047-1054, 2002 | 233 | 2002 |
| Comparison of synovial tissues from the knee joints and the small joints of rheumatoid arthritis patients: Implications for pathogenesis and evaluation of treatment MC Kraan, RJ Reece, TJM Smeets, DJ Veale, P Emery, PP Tak Arthritis & Rheumatism 46 (8), 2034-2038, 2002 | 225 | 2002 |
| The levels of soluble granzyme A and B are elevated in plasma and synovial fluid of patients with rheumatoid arthritis (RA) PP Tak, L Spaeny-Dekking, MC Kraan, FC Breedveld, CJ Froelich, ... Clinical & Experimental Immunology 116 (2), 366-370, 1999 | 224 | 1999 |
| Microarchitecture and protective mechanisms in synovial tissue from clinically and arthroscopically normal knee joints MD Smith, E Barg, H Weedon, V Papengelis, T Smeets, PP Tak, M Kraan, ... Annals of the rheumatic diseases 62 (4), 303-307, 2003 | 215 | 2003 |
| Analysis of the cell infiltrate and expression of proinflammatory cytokines and matrix metalloproteinases in arthroscopic synovial biopsies: comparison with synovial samples … TJM Smeets, EC Barg, MC Kraan, MD Smith, FC Breedveld, PP Tak Annals of the rheumatic diseases 62 (7), 635-638, 2003 | 214 | 2003 |
| Synovial microparticles from arthritic patients modulate chemokine and cytokine release by synoviocytes RJ Berckmans, R Nieuwland, MC Kraan, MCL Schaap, D Pots, ... Arthritis research & therapy 7, 1-9, 2005 | 212 | 2005 |
| Immunohistological analysis of synovial tissue for differential diagnosis in early arthritis MC Kraan, JJ Haringman, WJ Post, J Versendaal, FC Breedveld, PP Tak Rheumatology 38 (11), 1074-1080, 1999 | 205 | 1999 |
| The clinical response to infliximab in rheumatoid arthritis is in part dependent on pretreatment tumour necrosis factor αexpression in the synovium CA Wijbrandts, MGW Dijkgraaf, MC Kraan, M Vinkenoog, TJ Smeets, ... Annals of the rheumatic diseases 67 (8), 1139-1144, 2008 | 203 | 2008 |
| Alefacept treatment in psoriatic arthritis: reduction of the effector T cell population in peripheral blood and synovial tissue is associated with improvement of clinical signs … MC Kraan, AWR van Kuijk, HJ Dinant, AY Goedkoop, TJM Smeets, ... Arthritis & Rheumatism 46 (10), 2776-2784, 2002 | 193 | 2002 |
| Effects of oral prednisolone on biomarkers in synovial tissue and clinical improvement in rheumatoid arthritis DM Gerlag, JJ Haringman, TJM Smeets, AH Zwinderman, MC Kraan, ... Arthritis & Rheumatism 50 (12), 3783-3791, 2004 | 187 | 2004 |
| Folate receptor β as a potential delivery route for novel folate antagonists to macrophages in the synovial tissue of rheumatoid arthritis patients JW Van Der Heijden, R Oerlemans, BAC Dijkmans, H Qi, CJVD Laken, ... Arthritis & rheumatism 60 (1), 12-21, 2009 | 186 | 2009 |
Paul Peter TakCandel Therapeutics, GlaxoSmithKline, Kintai Therapeutics, Academic Medical Center, AmsterdamVerifisert e-postadresse på candeltx.com
