Discovery of 4-(4-(2-((5-Hydroxy-1, 2, 3, 4-tetrahydronaphthalen-2-yl)(propyl) amino) ethyl) piperazin-1-yl) quinolin-8-ol and its analogues as highly potent dopamine D2/D3 … B Ghosh, T Antonio, MEA Reith, AK Dutta Journal of medicinal chemistry 53 (5), 2114-2125, 2010 | 98 | 2010 |
Development of (S)-N6-(2-(4-(Isoquinolin-1-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]-thiazole-2,6-diamine and Its Analogue as a D3 … B Ghosh, T Antonio, J Zhen, P Kharkar, MEA Reith, AK Dutta Journal of medicinal chemistry 53 (3), 1023-1037, 2010 | 85 | 2010 |
Interaction of cocaine‐, benztropine‐, and GBR12909‐like compounds with wild‐type and mutant human dopamine transporters: molecular features that differentially determine … KC Schmitt, J Zhen, P Kharkar, M Mishra, N Chen, AK Dutta, MEA Reith Journal of neurochemistry 107 (4), 928-940, 2008 | 85 | 2008 |
Structure− activity relationship studies of novel 4-[2-[bis (4-fluorophenyl) methoxy] ethyl]-1-(3-phenylpropyl) piperidine analogs: synthesis and biological evaluation at the … AK Dutta, C Xu, MEA Reith Journal of medicinal chemistry 39 (3), 749-756, 1996 | 84 | 1996 |
Dopamine transporter as target for drug development of cocaine dependence medications AK Dutta, S Zhang, R Kolhatkar, MEA Reith European journal of pharmacology 479 (1-3), 93-106, 2003 | 80 | 2003 |
Further structure–activity relationships study of hybrid 7-{[2-(4-phenylpiperazin-1-yl) ethyl] propylamino}-5, 6, 7, 8-tetrahydronaphthalen-2-ol analogues: identification of a … S Biswas, S Zhang, F Fernandez, B Ghosh, J Zhen, E Kuzhikandathil, ... Journal of medicinal chemistry 51 (1), 101-117, 2008 | 70 | 2008 |
Synthesis and biological characterization of novel hybrid 7-{[2-(4-phenyl-piperazin-1-yl)-ethyl]-propyl-amino}-5, 6, 7, 8-tetrahydro-naphthalen-2-ol and their heterocyclic … AK Dutta, SK Venkataraman, XS Fei, R Kolhatkar, S Zhang, MEA Reith Bioorganic & medicinal chemistry 12 (16), 4361-4373, 2004 | 68 | 2004 |
Novel D3 dopamine receptor‐preferring agonist D‐264: Evidence of neuroprotective property in Parkinson's disease animal models induced by 1‐methyl‐4‐phenyl‐1, 2, 3, 6 … C Li, S Biswas, X Li, AK Dutta, W Le Journal of neuroscience research 88 (11), 2513-2523, 2010 | 67 | 2010 |
Structure–Activity Relationship Study of N6-(2-(4-(1H-Indol-5-yl)piperazin-1-yl)ethyl)-N6-propyl-4,5,6,7-tetrahydrobenzo[d]thiazole-2,6-diamine Analogues … M Johnson, T Antonio, MEA Reith, AK Dutta Journal of medicinal chemistry 55 (12), 5826-5840, 2012 | 66 | 2012 |
Highly selective, novel analogs of 4-[2-(diphenylmethoxy) ethyl]-1-benzylpiperidine for the dopamine transporter: effect of different aromatic substitutions on their affinity … AK Dutta, LL Coffey, MEA Reith Journal of medicinal chemistry 40 (1), 35-43, 1997 | 65 | 1997 |
Inhibition of alpha-synuclein aggregation by multifunctional dopamine agonists assessed by a novel in vitro assay and an in vivo Drosophila synucleinopathy model D Yedlapudi, GS Joshi, D Luo, SV Todi, AK Dutta Scientific reports 6 (1), 38510, 2016 | 63 | 2016 |
Bioisosteric heterocyclic versions of 7-{[2-(4-phenyl-piperazin-1-yl) ethyl] propylamino}-5, 6, 7, 8-tetrahydronaphthalen-2-ol: identification of highly potent and selective … S Biswas, S Hazeldine, B Ghosh, I Parrington, E Kuzhikandathil, ... Journal of medicinal chemistry 51 (10), 3005-3019, 2008 | 63 | 2008 |
Multi-objective optimization of hybrid laminates subjected to transverse impact G Sandeep, D Chakraborty, A Dutta Composite Structures 73 (3), 360-369, 2006 | 60 | 2006 |
Triple reuptake inhibitors as potential next-generation antidepressants: a new hope? H Sharma, S Santra, A Dutta Future medicinal chemistry 7 (17), 2385-2406, 2015 | 58 | 2015 |
A novel series of hybrid compounds derived by combining 2-aminotetralin and piperazine fragments: binding activity at D2 and D3 receptors AK Dutta, XS Fei, MEA Reith Bioorganic & medicinal chemistry letters 12 (4), 619-622, 2002 | 56 | 2002 |
Positional Importance of the Nitrogen Atom in Novel Piperidine Analogues of GBR 12909: Affinity and Selectivity for the Dopamine Transporter. AK Dutta, PC Meltzer, BK Madras ChemInform 25 (16), no-no, 1994 | 56 | 1994 |
α-Synuclein aggregation modulation: an emerging approach for the treatment of Parkinson's disease SK Singh, A Dutta, G Modi Future medicinal chemistry 9 (10), 1039-1053, 2017 | 54 | 2017 |
Potent and selective ligands for the dopamine transporter (DAT): Structure− activity relationship studies of novel 4-[2-(diphenylmethoxy) ethyl]-1-(3-phenylpropyl) piperidine … AK Dutta, LL Coffey, MEA Reith Journal of medicinal chemistry 41 (5), 699-705, 1998 | 52 | 1998 |
Magnetic and electric properties of antimony selenide (Sb2Se3) crystals BR Chakraborty, B Ray, R Bhattacharya, AK Dutta Journal of Physics and Chemistry of Solids 41 (8), 913-917, 1980 | 51 | 1980 |
Dual incorporation of photoaffinity ligands on dopamine transporters implicates proximity of labeled domains RA Vaughan, JD Gaffaney, JR Lever, MEA Reith, AK Dutta Molecular Pharmacology 59 (5), 1157-1164, 2001 | 48 | 2001 |