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Kenneth P.  Nephew
Kenneth P. Nephew
Jerry W. and Peggy S. Throgmartin Chair in Oncology
Verifisert e-postadresse på indiana.edu - Startside
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Identification and characterization of ovarian cancer-initiating cells from primary human tumors
S Zhang, C Balch, MW Chan, HC Lai, D Matei, JM Schilder, PS Yan, ...
Cancer research 68 (11), 4311-4320, 2008
16892008
Rethinking ovarian cancer: recommendations for improving outcomes
S Vaughan, JI Coward, RC Bast Jr, A Berchuck, JS Berek, JD Brenton, ...
Nature Reviews Cancer 11 (10), 719-725, 2011
15472011
Rethinking ovarian cancer II: reducing mortality from high-grade serous ovarian cancer
DD Bowtell, S Böhm, AA Ahmed, PJ Aspuria, RC Bast Jr, V Beral, ...
Nature reviews Cancer 15 (11), 668-679, 2015
12442015
Epigenetic resensitization to platinum in ovarian cancer
D Matei, F Fang, C Shen, J Schilder, A Arnold, Y Zeng, WA Berry, ...
Cancer research 72 (9), 2197-2205, 2012
4352012
MicroRNA cluster 221-222 and estrogen receptor α interactions in breast cancer
G Di Leva, P Gasparini, C Piovan, A Ngankeu, M Garofalo, C Taccioli, ...
JNCI: Journal of the National Cancer Institute 102 (10), 706-721, 2010
4292010
MicroRNA-221/222 confers breast cancer fulvestrant resistance by regulating multiple signaling pathways
X Rao, G Di Leva, M Li, F Fang, C Devlin, C Hartman-Frey, ME Burow, ...
Oncogene 30 (9), 1082-1097, 2011
4232011
Alcohol exposure alters DNA methylation profiles in mouse embryos at early neurulation
Y Liu, Y Balaraman, G Wang, KP Nephew, FC Zhou
Epigenetics 4 (7), 500-511, 2009
2942009
Diverse gene expression and DNA methylation profiles correlate with differential adaptation of breast cancer cells to the antiestrogens tamoxifen and fulvestrant
M Fan, PS Yan, C Hartman-Frey, L Chen, H Paik, SL Oyer, JD Salisbury, ...
Cancer research 66 (24), 11954-11966, 2006
2902006
Epigenetic gene silencing in cancer initiation and progression
KP Nephew, THM Huang
Cancer letters 190 (2), 125-133, 2003
2762003
NF-κB-HOTAIR axis links DNA damage response, chemoresistance and cellular senescence in ovarian cancer
AR Özeş, DF Miller, ON Özeş, F Fang, Y Liu, D Matei, T Huang, ...
Oncogene 35 (41), 5350-5361, 2016
2752016
Integrated analysis of DNA methylation and gene expression reveals specific signaling pathways associated with platinum resistance in ovarian cancer
M Li, C Balch, JS Montgomery, M Jeong, JH Chung, P Yan, THM Huang, ...
BMC medical genomics 2, 1-13, 2009
2432009
Epithelial ovarian cancer experimental models
E Lengyel, JE Burdette, HA Kenny, D Matei, J Pilrose, P Haluska, ...
Oncogene 33 (28), 3619-3633, 2014
2392014
Methylation microarray analysis of late-stage ovarian carcinomas distinguishes progression-free survival in patients and identifies candidate epigenetic markers
SH Wei, CM Chen, G Strathdee, J Harnsomburana, CR Shyu, ...
Clinical Cancer Research 8 (7), 2246-2252, 2002
2382002
Loss of estrogen receptor signaling triggers epigenetic silencing of downstream targets in breast cancer
YW Leu, PS Yan, M Fan, VX Jin, JC Liu, EM Curran, WV Welshons, ...
Cancer research 64 (22), 8184-8192, 2004
2312004
Combinatorial analysis of transcription factor partners reveals recruitment of c-MYC to estrogen receptor-α responsive promoters
ASL Cheng, VX Jin, M Fan, LT Smith, S Liyanarachchi, PS Yan, YW Leu, ...
Molecular cell 21 (3), 393-404, 2006
2182006
Fulvestrant (ICI 182,780)-dependent interacting proteins mediate immobilization and degradation of estrogen receptor-α
X Long, KP Nephew
Journal of Biological Chemistry 281 (14), 9607-9615, 2006
2172006
CHIP (carboxyl terminus of Hsc70-interacting protein) promotes basal and geldanamycin-induced degradation of estrogen receptor-α
M Fan, A Park, KP Nephew
Molecular endocrinology 19 (12), 2901-2914, 2005
2152005
In vivo tumor growth of high-grade serous ovarian cancer cell lines
AK Mitra, DA Davis, S Tomar, L Roy, H Gurler, J Xie, DD Lantvit, ...
Gynecologic oncology 138 (2), 372-377, 2015
2112015
The epigenetics of ovarian cancer drug resistance and resensitization
C Balch, THM Huang, R Brown, KP Nephew
American journal of obstetrics and gynecology 191 (5), 1552-1572, 2004
2072004
EGFR signaling in breast cancer: bad to the bone
J Foley, NK Nickerson, S Nam, KT Allen, JL Gilmore, KP Nephew, ...
Seminars in cell & developmental biology 21 (9), 951-960, 2010
2022010
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