| Synthesis of proteins by native chemical ligation PE Dawson, TW Muir, I Clark-Lewis, SBH Kent Science 266 (5186), 776-779, 1994 | 4995 | 1994 |
| Expressed protein ligation: a general method for protein engineering TW Muir, D Sondhi, PA Cole Proceedings of the National Academy of Sciences 95 (12), 6705-6710, 1998 | 1535 | 1998 |
| Inhibition of PRC2 activity by a gain-of-function H3 mutation found in pediatric glioblastoma PW Lewis, MM Müller, MS Koletsky, F Cordero, S Lin, LA Banaszynski, ... Science 340 (6134), 857-861, 2013 | 1354 | 2013 |
| Semisynthesis of proteins by expressed protein ligation TW Muir Annual review of biochemistry 72 (1), 249-289, 2003 | 896 | 2003 |
| Histone H2A deubiquitinase activity of the Polycomb repressive complex PR-DUB JC Scheuermann, AG de Ayala Alonso, K Oktaba, N Ly-Hartig, ... Nature 465 (7295), 243-247, 2010 | 887 | 2010 |
| How many human proteoforms are there? R Aebersold, JN Agar, IJ Amster, MS Baker, CR Bertozzi, ES Boja, ... Nature chemical biology 14 (3), 206-214, 2018 | 885 | 2018 |
| Structure-activity analysis of synthetic autoinducing thiolactone peptides from Staphylococcus aureus responsible for virulence P Mayville, G Ji, R Beavis, H Yang, M Goger, RP Novick, TW Muir Proceedings of the National Academy of Sciences 96 (4), 1218-1223, 1999 | 627 | 1999 |
| Chemically ubiquitylated histone H2B stimulates hDot1L-mediated intranucleosomal methylation RK McGinty, J Kim, C Chatterjee, RG Roeder, TW Muir Nature 453 (7196), 812-816, 2008 | 611 | 2008 |
| RAD6-Mediated transcription-coupled H2B ubiquitylation directly stimulates H3K4 methylation in human cells J Kim, M Guermah, RK McGinty, JS Lee, Z Tang, TA Milne, A Shilatifard, ... Cell 137 (3), 459-471, 2009 | 607 | 2009 |
| The TGFβ receptor activation process: an inhibitor-to substrate-binding switch M Huse, TW Muir, L Xu, YG Chen, J Kuriyan, J Massagué Molecular cell 8 (3), 671-682, 2001 | 540 | 2001 |
| Histone H2B ubiquitylation disrupts local and higher-order chromatin compaction B Fierz, C Chatterjee, RK McGinty, M Bar-Dagan, DP Raleigh, TW Muir Nature chemical biology 7 (2), 113-119, 2011 | 510 | 2011 |
| Inteins: nature's gift to protein chemists NH Shah, TW Muir Chemical science 5 (2), 446-461, 2014 | 459 | 2014 |
| Protein ligation: an enabling technology for the biophysical analysis of proteins V Muralidharan, TW Muir Nature methods 3 (6), 429-438, 2006 | 453 | 2006 |
| Crystal structure of a phosphorylated Smad2: Recognition of phosphoserine by the MH2 domain and insights on Smad function in TGF-β signaling JW Wu, M Hu, J Chai, J Seoane, M Huse, C Li, DJ Rigotti, S Kyin, TW Muir, ... Molecular cell 8 (6), 1277-1289, 2001 | 437 | 2001 |
| Recognition of a mononucleosomal histone modification pattern by BPTF via multivalent interactions AJ Ruthenburg, H Li, TA Milne, S Dewell, RK McGinty, M Yuen, ... Cell 145 (5), 692-706, 2011 | 408 | 2011 |
| Histone serotonylation is a permissive modification that enhances TFIID binding to H3K4me3 LA Farrelly, RE Thompson, S Zhao, AE Lepack, Y Lyu, NV Bhanu, ... Nature 567 (7749), 535-539, 2019 | 397 | 2019 |
| Histone H3K36 mutations promote sarcomagenesis through altered histone methylation landscape C Lu, SU Jain, D Hoelper, D Bechet, RC Molden, L Ran, D Murphy, ... Science 352 (6287), 844-849, 2016 | 396 | 2016 |
| Exfoliatin-Producing Strains Define a Fourthagr Specificity Group in Staphylococcus aureus S Jarraud, GJ Lyon, AMS Figueiredo, L Gérard, F Vandenesch, J Etienne, ... Journal of bacteriology 182 (22), 6517-6522, 2000 | 374 | 2000 |
| Rational design of a global inhibitor of the virulence response in Staphylococcus aureus, based in part on localization of the site of inhibition to the receptor … GJ Lyon, P Mayville, TW Muir, RP Novick Proceedings of the National Academy of Sciences 97 (24), 13330-13335, 2000 | 359 | 2000 |
| The expanding landscape of ‘oncohistone’mutations in human cancers BA Nacev, L Feng, JD Bagert, AE Lemiesz, JJ Gao, AA Soshnev, ... Nature 567 (7749), 473-478, 2019 | 346 | 2019 |