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Sara Pensa
Sara Pensa
Research Associate, University of Cambridge
Verifisert e-postadresse på cam.ac.uk
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STAT1 and STAT3 in tumorigenesis: A matter of balance
L Avalle, S Pensa, G Regis, F Novelli, V Poli
Jak-stat 1 (2), 65-72, 2012
3092012
Differentiation dynamics of mammary epithelial cells revealed by single-cell RNA sequencing
K Bach, S Pensa, M Grzelak, J Hadfield, DJ Adams, JC Marioni, ...
Nature communications 8 (1), 1-11, 2017
2992017
Ups and downs: the STAT1: STAT3 seesaw of Interferon and gp130 receptor signalling
G Regis, S Pensa, D Boselli, F Novelli, V Poli
Seminars in cell & developmental biology 19 (4), 351-359, 2008
2712008
Constitutively active Stat3 enhances neu-mediated migration and metastasis in mammary tumors via upregulation of Cten
I Barbieri, S Pensa, T Pannellini, E Quaglino, D Maritano, M Demaria, ...
Cancer research 70 (6), 2558-2567, 2010
1742010
Stat3 and the inflammation/acute phase response in involution and breast cancer
S Pensa, CJ Watson, V Poli
Journal of mammary gland biology and neoplasia 14, 121-129, 2009
982009
STAT1 and STAT3 in tumorigenesis
S Pensa, G Regis, D Boselli, F Novelli, V Poli
JAK-STAT pathway in disease. Texas: Landes Bioscience Books, 100-121, 2009
932009
BCL11A interacts with SOX2 to control the expression of epigenetic regulators in lung squamous carcinoma
KA Lazarus, F Hadi, E Zambon, K Bach, MF Santolla, JK Watson, ...
Nature communications 9 (1), 3327, 2018
682018
Transcriptional changes in the mammary gland during lactation revealed by single cell sequencing of cells from human milk
AJ Twigger, LK Engelbrecht, K Bach, I Schultz-Pernice, S Pensa, ...
Nature communications 13 (1), 562, 2022
532022
Time-resolved single-cell analysis of Brca1 associated mammary tumourigenesis reveals aberrant differentiation of luminal progenitors
K Bach, S Pensa, M Zarocsinceva, K Kania, J Stockis, S Pinaud, ...
Nature communications 12 (1), 1502, 2021
502021
Constitutive activation of JAK2 in mammary epithelium elevates Stat5 signalling, promotes alveologenesis and resistance to cell death, and contributes to tumourigenesis
MM Caffarel, R Zaragoza, S Pensa, J Li, AR Green, CJ Watson
Cell Death & Differentiation 19 (3), 511-522, 2012
382012
Tumour cell invasiveness and response to chemotherapeutics in adipocyte invested 3D engineered anisotropic collagen scaffolds
RD Hume, S Pensa, EJ Brown, PA Kreuzaler, J Hitchcock, A Husmann, ...
Scientific reports 8 (1), 12658, 2018
372018
MicroRNAs-143 and-145 induce epithelial to mesenchymal transition and modulate the expression of junction proteins
L Avalle, D Incarnato, A Savino, M Gai, F Marino, S Pensa, I Barbieri, ...
Cell Death & Differentiation 24 (10), 1750-1760, 2017
292017
Stat3 is required to maintain the full differentiation potential of mammary stem cells and the proliferative potential of mammary luminal progenitors
AD Staniszewska, S Pensa, MM Caffarel, LH Anderson, V Poli, CJ Watson
PLoS One 7 (12), e52608, 2012
252012
A single-cell atlas enables mapping of homeostatic cellular shifts in the adult human breast
AD Reed, S Pensa, A Steif, J Stenning, DJ Kunz, LJ Porter, K Hua, P He, ...
Nature Genetics 56 (4), 652-662, 2024
232024
Signal transducer and activator of transcription 3 and the phosphatidylinositol 3‐kinase regulatory subunits p55α and p50α regulate autophagy in vivo
S Pensa, B Lloyd‐Lewis, TJ Sargeant, HK Resemann, CR Kahn, ...
The FEBS journal 281 (20), 4557-4567, 2014
232014
The PI3K regulatory subunits p55α and p50α regulate cell death in vivo
S Pensa, K Neoh, HK Resemann, PA Kreuzaler, K Abell, NJ Clarke, ...
Cell Death & Differentiation 21 (9), 1442-1450, 2014
152014
Stat3 modulates chloride channel accessory protein expression in normal and neoplastic mammary tissue
K Hughes, M Blanck, S Pensa, CJ Watson
Cell Death & Disease 7 (10), e2398-e2398, 2016
132016
The immune environment of the mammary gland fluctuates during post-lactational regression and correlates with tumour growth rate
J Hitchcock, K Hughes, S Pensa, B Lloyd-Lewis, CJ Watson
Development 149 (8), dev200162, 2022
122022
Molecular biology of breast cancer
MM Caffarel, S Pensa, JA Wickenden, CJ Watson
eLS, 1-9, 2016
102016
A human breast cell atlas mapping the homeostatic cellular shifts in the adult breast
AD Reed, S Pensa, A Steif, J Stenning, DJ Kunz, P He, AJ Twigger, ...
bioRxiv, 2023.04. 21.537845, 2023
82023
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Artikler 1–20