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Mark Brynildsen
Mark Brynildsen
Professor of Chemical and Biological Engineering, Princeton University
Verifisert e-postadresse på princeton.edu - Startside
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Definitions and guidelines for research on antibiotic persistence
NQ Balaban, S Helaine, K Lewis, M Ackermann, B Aldridge, DI Andersson, ...
Nature Reviews Microbiology 17 (7), 441-448, 2019
11172019
Metabolic engineering of Escherichia coli for 1-butanol production
S Atsumi, AF Cann, MR Connor, CR Shen, KM Smith, MP Brynildsen, ...
Metabolic engineering 10 (6), 305-311, 2008
11102008
Metabolite-enabled eradication of bacterial persisters by aminoglycosides
KR Allison, MP Brynildsen, JJ Collins
Nature 473 (7346), 216-220, 2011
10682011
Potentiating antibacterial activity by predictably enhancing endogenous microbial ROS production
MP Brynildsen, JA Winkler, CS Spina, IC MacDonald, JJ Collins
Nature biotechnology 31 (2), 160-165, 2013
4722013
Metabolic control of persister formation in Escherichia coli
SM Amato, MA Orman, MP Brynildsen
Molecular cell 50 (4), 475-487, 2013
4172013
The role of metabolism in bacterial persistence
SM Amato, CH Fazen, TC Henry, WWK Mok, MA Orman, EL Sandvik, ...
Frontiers in microbiology 5, 70, 2014
2942014
Dormancy is not necessary or sufficient for bacterial persistence
MA Orman, MP Brynildsen
Antimicrobial agents and chemotherapy 57 (7), 3230-3239, 2013
2912013
An integrated network approach identifies the isobutanol response network of Escherichia coli
MP Brynildsen, JC Liao
Molecular systems biology 5 (1), 277, 2009
2452009
Heterogeneous bacterial persisters and engineering approaches to eliminate them
KR Allison, MP Brynildsen, JJ Collins
Current opinion in microbiology 14 (5), 593-598, 2011
2352011
Enhanced antibiotic resistance development from fluoroquinolone persisters after a single exposure to antibiotic
TC Barrett, WWK Mok, AM Murawski, MP Brynildsen
Nature communications 10 (1), 1177, 2019
1812019
Persister heterogeneity arising from a single metabolic stress
SM Amato, MP Brynildsen
Current Biology 25 (16), 2090-2098, 2015
1652015
Inhibition of stationary phase respiration impairs persister formation in E. coli
MA Orman, MP Brynildsen
Nature communications 6 (1), 7983, 2015
1512015
Establishment of a method to rapidly assay bacterial persister metabolism
MA Orman, MP Brynildsen
Antimicrobial agents and chemotherapy 57 (9), 4398-4409, 2013
1442013
Nutrient transitions are a source of persisters in Escherichia coli biofilms
SM Amato, MP Brynildsen
PloS one 9 (3), e93110, 2014
1292014
Stationary-phase persisters to ofloxacin sustain DNA damage and require repair systems only during recovery
KG Völzing, MP Brynildsen
MBio 6 (5), 10.1128/mbio. 00731-15, 2015
1212015
gNCA: a framework for determining transcription factor activity based on transcriptome: identifiability and numerical implementation
LM Tran, MP Brynildsen, KC Kao, JK Suen, JC Liao
Metabolic engineering 7 (2), 128-141, 2005
1202005
Timing of DNA damage responses impacts persistence to fluoroquinolones
WWK Mok, MP Brynildsen
Proceedings of the National Academy of Sciences 115 (27), E6301-E6309, 2018
1012018
Inferring yeast cell cycle regulators and interactions using transcription factor activities
YL Yang, J Suen, MP Brynildsen, SJ Galbraith, JC Liao
Bmc Genomics 6, 1-15, 2005
842005
Futile cycling increases sensitivity toward oxidative stress in Escherichia coli
KJ Adolfsen, MP Brynildsen
Metabolic engineering 29, 26-35, 2015
712015
A Kinetic Platform to Determine the Fate of Nitric Oxide in Escherichia coli
JL Robinson, MP Brynildsen
PLoS computational biology 9 (5), e1003049, 2013
612013
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Artikler 1–20