Piezo1 forms mechanosensitive ion channels in the human MCF-7 breast cancer cell line C Li, S Rezania, S Kammerer, A Sokolowski, T Devaney, A Gorischek, ... Scientific reports 5 (1), 8364, 2015 | 180 | 2015 |
Phycocyanin from Arthrospira platensis as Potential Anti-Cancer Drug: Review of In Vitro and In Vivo Studies S Braune, A Krüger-Genge, S Kammerer, F Jung, JH Küpper Life 11 (2), 91, 2021 | 112 | 2021 |
Human hepatocyte systems for in vitro toxicology analysis S Kammerer, JH Küpper Journal of Cellular Biotechnology 3 (2), 85-93, 2018 | 53 | 2018 |
Three-dimensional liver culture systems to maintain primary hepatic properties for toxicological analysis in vitro S Kammerer International journal of molecular sciences 22 (19), 10214, 2021 | 42 | 2021 |
ATP-based cell viability assay is superior to trypan blue exclusion and XTT assay in measuring cytotoxicity of anticancer drugs Taxol and Imatinib, and proteasome inhibitor MG … E Nowak, S Kammerer, JH Küpper Clinical hemorheology and microcirculation 69 (1-2), 327-336, 2018 | 34 | 2018 |
Multifactorial resistance to aminopeptidase inhibitor prodrug CHR2863 in myeloid leukemia cells: down-regulation of carboxylesterase 1, drug sequestration in lipid droplets and … SE Verbrugge, M Al, YG Assaraf, S Kammerer, DMSH Chandrupatla, ... Oncotarget 7 (5), 5240, 2015 | 34 | 2015 |
Synthesis of cyclophosphamide metabolites by a peroxygenase from Marasmius rotula for toxicological studies on human cancer cells S Steinbrecht, J Kiebist, R König, M Thiessen, KU Schmidtke, ... AMB Express 10, 1-13, 2020 | 26 | 2020 |
Metabolic activity testing can underestimate acute drug cytotoxicity as revealed by HepG2 cell clones overexpressing cytochrome P450 2C19 and 3A4 S Steinbrecht, R König, KU Schmidtke, N Herzog, K Scheibner, ... Toxicology 412, 37-47, 2019 | 26 | 2019 |
Brivanib Exhibits Potential for Pharmacokinetic Drug–Drug Interactions and the Modulation of Multidrug Resistance through the Inhibition of Human ABCG2 Drug Efflux Transporter … J Hofman, A Sorf, D Vagiannis, S Sucha, S Kammerer, JH Küpper, ... Molecular pharmaceutics 16 (11), 4436-4450, 2019 | 25 | 2019 |
Ensartinib (X-396) effectively modulates pharmacokinetic resistance mediated by ABCB1 and ABCG2 drug efflux transporters and CYP3A4 biotransformation enzyme D Vagiannis, E Novotna, A Skarka, S Kammerer, JH Küpper, S Chen, ... Cancers 12 (4), 813, 2020 | 24 | 2020 |
KCNJ3 is a new independent prognostic marker for estrogen receptor positive breast cancer patients S Kammerer, A Sokolowski, H Hackl, D Platzer, SW Jahn, A El-Heliebi, ... Oncotarget 7 (51), 84705, 2016 | 21 | 2016 |
Interactions of alectinib with human ATP-binding cassette drug efflux transporters and cytochrome P450 biotransformation enzymes: effect on pharmacokinetic multidrug resistance J Hofman, A Sorf, D Vagiannis, S Sucha, E Novotna, S Kammerer, ... Drug Metabolism and Disposition 47 (7), 699-709, 2019 | 20 | 2019 |
Real time monitoring of oxygen uptake of hepatocytes in a microreactor using optical microsensors C Gehre, M Flechner, S Kammerer, JH Küpper, CD Coleman, GP Püschel, ... Scientific reports 10 (1), 13700, 2020 | 18 | 2020 |
Effects of acrolein in comparison to its prodrug cyclophosphamide on human primary endothelial cells in vitro S Lau, R Rangarajan, C Philidet, A Krüger-Genge, S Braune, S Kammerer, ... Toxicology in Vitro 62, 104685, 2020 | 18 | 2020 |
HepG2 cells with recombinant cytochrome P450 enzyme overexpression: Their use and limitation as in vitro liver model S Steinbrecht, S Kammerer, JH Küpper Journal of Cellular Biotechnology 5 (1), 55-64, 2019 | 16 | 2019 |
Overexpression of KCNJ3 gene splice variants affects vital parameters of the malignant breast cancer cell line MCF-7 in an opposing manner S Rezania, S Kammerer, C Li, B Steinecker-Frohnwieser, A Gorischek, ... BMC cancer 16, 1-15, 2016 | 16 | 2016 |
NADPH-cytochrome P450 reductase expression and enzymatic activity in primary-like human hepatocytes and HepG2 cells for in vitro biotransformation studies C Schulz, S Kammerer, JH Küpper Clinical hemorheology and microcirculation 73 (1), 249-260, 2019 | 15 | 2019 |
HepG2-1A2 C2 and C7: Lentivirus vector-mediated stable and functional overexpression of cytochrome P450 1A2 in human hepatoblastoma cells S Steinbrecht, N Pfeifer, N Herzog, N Katzenberger, C Schulz, ... Toxicology letters 319, 155-159, 2020 | 13 | 2020 |
Alisertib shows negligible potential for perpetrating pharmacokinetic drug-drug interactions on ABCB1, ABCG2 and cytochromes P450, but acts as dual-activity resistance … D Vagiannis, Y Zhang, Y Budagaga, E Novotna, A Skarka, S Kammerer, ... Toxicology and Applied Pharmacology 434, 115823, 2022 | 12 | 2022 |
Tepotinib inhibits several drug efflux transporters and biotransformation enzymes: the role in drug-drug interactions and targeting cytostatic resistance in vitro and ex vivo D Vagiannis, Y Budagaga, A Morell, Y Zhang, E Novotná, A Skarka, ... International Journal of Molecular Sciences 22 (21), 11936, 2021 | 8 | 2021 |