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Bruno Canard
Bruno Canard
Directeur de Recherches CNRS, AMU
Verifisert e-postadresse på univ-amu.fr - Startside
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The spike glycoprotein of the new coronavirus 2019-nCoV contains a furin-like cleavage site absent in CoV of the same clade
B Coutard, C Valle, X De Lamballerie, B Canard, NG Seidah, E Decroly
Antiviral research 176, 104742, 2020
20502020
SAMHD1 restricts the replication of human immunodeficiency virus type 1 by depleting the intracellular pool of deoxynucleoside triphosphates
H Lahouassa, W Daddacha, H Hofmann, D Ayinde, EC Logue, L Dragin, ...
Nature immunology 13 (3), 223-228, 2012
9752012
An RNA cap (nucleoside‐2′‐O‐)‐methyltransferase in the flavivirus RNA polymerase NS5: crystal structure and functional characterization
MP Egloff, D Benarroch, B Selisko, JL Romette, B Canard
The EMBO journal, 2002
7652002
Discovery of an RNA virus 3′→ 5′ exoribonuclease that is critically involved in coronavirus RNA synthesis
E Minskaia, T Hertzig, AE Gorbalenya, V Campanacci, C Cambillau, ...
Proceedings of the National Academy of Sciences 103 (13), 5108-5113, 2006
7172006
One severe acute respiratory syndrome coronavirus protein complex integrates processive RNA polymerase and exonuclease activities
L Subissi, CC Posthuma, A Collet, JC Zevenhoven-Dobbe, ...
Proceedings of the National Academy of Sciences 111 (37), E3900-E3909, 2014
6672014
Conventional and unconventional mechanisms for capping viral mRNA
E Decroly, F Ferron, J Lescar, B Canard
Nature Reviews Microbiology 10 (1), 51-65, 2012
5252012
Assessing protein disorder and induced folding
V Receveur‐Bréchot, JM Bourhis, VN Uversky, B Canard, S Longhi
Proteins: Structure, Function, and Bioinformatics 62 (1), 24-45, 2006
5092006
Crystal structure of the dengue virus RNA-dependent RNA polymerase catalytic domain at 1.85-angstrom resolution
TL Yap, T Xu, YL Chen, H Malet, MP Egloff, B Canard, SG Vasudevan, ...
Journal of virology 81 (9), 4753-4765, 2007
4972007
Structure and functionality in flavivirus NS-proteins: perspectives for drug design
M Bollati, K Alvarez, R Assenberg, C Baronti, B Canard, S Cook, ...
Antiviral research 87 (2), 125-148, 2010
4482010
In Vitro Reconstitution of SARS-Coronavirus mRNA Cap Methylation
M Bouvet, C Debarnot, I Imbert, B Selisko, EJ Snijder, B Canard, ...
PLoS pathogens 6 (4), e1000863, 2010
4302010
Structural and molecular basis of mismatch correction and ribavirin excision from coronavirus RNA
F Ferron, L Subissi, AT Silveira De Morais, NTT Le, M Sevajol, L Gluais, ...
Proceedings of the National Academy of Sciences 115 (2), E162-E171, 2018
4102018
The severe acute respiratory syndrome-coronavirus replicative protein nsp9 is a single-stranded RNA-binding subunit unique in the RNA virus world
MP Egloff, F Ferron, V Campanacci, S Longhi, C Rancurel, H Dutartre, ...
Proceedings of the National Academy of Sciences 101 (11), 3792-3796, 2004
3942004
Crystal structure and functional analysis of the SARS-coronavirus RNA cap 2′-O-methyltransferase nsp10/nsp16 complex
E Decroly, C Debarnot, F Ferron, M Bouvet, B Coutard, I Imbert, L Gluais, ...
PLoS pathogens 7 (5), e1002059, 2011
3822011
RNA 3'-end mismatch excision by the severe acute respiratory syndrome coronavirus nonstructural protein nsp10/nsp14 exoribonuclease complex
M Bouvet, I Imbert, L Subissi, L Gluais, B Canard, E Decroly
Proceedings of the National Academy of Sciences 109 (24), 9372-9377, 2012
3742012
Remdesivir and SARS-CoV-2: Structural requirements at both nsp12 RdRp and nsp14 Exonuclease active-sites
A Shannon, NTT Le, B Selisko, C Eydoux, K Alvarez, JC Guillemot, ...
Antiviral research 178, 104793, 2020
3472020
A practical overview of protein disorder prediction methods
F Ferron, S Longhi, B Canard, D Karlin
Proteins: Structure, Function, and Bioinformatics 65 (1), 1-14, 2006
3472006
A second, non‐canonical RNA‐dependent RNA polymerase in SARS Coronavirus
I Imbert, JC Guillemot, JM Bourhis, C Bussetta, B Coutard, MP Egloff, ...
The EMBO journal 25 (20), 4933-4942, 2006
3452006
The C-terminal domain of the measles virus nucleoprotein is intrinsically disordered and folds upon binding to the C-terminal moiety of the phosphoprotein
S Longhi, V Receveur-Bréchot, D Karlin, K Johansson, H Darbon, ...
Journal of Biological Chemistry 278 (20), 18638-18648, 2003
3322003
Coronavirus Nonstructural Protein 16 Is a Cap-0 Binding Enzyme Possessing (Nucleoside-2′O)-Methyltransferase Activity
E Decroly, I Imbert, B Coutard, M Bouvet, B Selisko, K Alvarez, ...
Journal of virology 82 (16), 8071-8084, 2008
3062008
Crystal structure of the RNA polymerase domain of the West Nile virus non-structural protein 5
H Malet, MP Egloff, B Selisko, RE Butcher, PJ Wright, M Roberts, A Gruez, ...
Journal of Biological Chemistry 282 (14), 10678-10689, 2007
2882007
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