Tobacco-specific carcinogen 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) induces cell proliferation in normal human bronchial epithelial cells through NFκB activation … YS Ho, CH Chen, YJ Wang, RG Pestell, C Albanese, RJ Chen, MC Chang, ... Toxicology and applied pharmacology 205 (2), 133-148, 2005 | 132 | 2005 |
Nanoplastics impact the zebrafish (Danio rerio) transcriptome: Associated developmental and neurobehavioral consequences AF Pedersen, DN Meyer, AMV Petriv, AL Soto, JN Shields, C Akemann, ... Environmental Pollution 266, 115090, 2020 | 126 | 2020 |
An optimal ubiquitin-proteasome pathway in the nervous system: the role of deubiquitinating enzymes G Ristic, WL Tsou, SV Todi Frontiers in molecular neuroscience 7, 72, 2014 | 102 | 2014 |
Systematic analysis of the physiological importance of deubiquitinating enzymes WL Tsou, MJ Sheedlo, ME Morrow, JR Blount, KM McGregor, C Das, ... Public Library of Science 7 (8), e43112, 2012 | 80 | 2012 |
Ubiquitin-binding site 2 of ataxin-3 prevents its proteasomal degradation by interacting with Rad23 JR Blount, WL Tsou, G Ristic, AA Burr, M Ouyang, H Galante, ... Nature communications 5 (1), 4638, 2014 | 74 | 2014 |
Ubiquitination regulates the neuroprotective function of the deubiquitinase ataxin-3 in vivo WL Tsou, AA Burr, M Ouyang, JR Blount, KM Scaglione, SV Todi Journal of Biological Chemistry 288 (48), 34460-34469, 2013 | 67 | 2013 |
The deubiquitinase ataxin-3 requires Rad23 and DnaJ-1 for its neuroprotective role in Drosophila melanogaster WL Tsou, M Ouyang, RR Hosking, JR Sutton, JR Blount, AA Burr, SV Todi Neurobiology of disease 82, 12-21, 2015 | 56 | 2015 |
Using membrane‐targeted green fluorescent protein to monitor neurotoxic protein‐dependent degeneration of Drosophila eyes AA Burr, WL Tsou, G Ristic, SV Todi Journal of neuroscience research 92 (9), 1100-1109, 2014 | 50 | 2014 |
DnaJ-1 and karyopherin α3 suppress degeneration in a new Drosophila model of Spinocerebellar Ataxia Type 6 WL Tsou, RR Hosking, AA Burr, JR Sutton, M Ouyang, X Du, CM Gomez, ... Human molecular genetics 24 (15), 4385-4396, 2015 | 47 | 2015 |
Interaction of the polyglutamine protein ataxin-3 with Rad23 regulates toxicity in Drosophila models of Spinocerebellar Ataxia Type 3 JR Sutton, JR Blount, K Libohova, WL Tsou, GS Joshi, HL Paulson, ... Human molecular genetics 26 (8), 1419-1431, 2017 | 42 | 2017 |
Checkpoint kinase 1‐mediated phosphorylation of Cdc25C and bad proteins are involved in antitumor effects of loratadine‐induced G2/M phase cell‐cycle arrest … JS Chen, SY Lin, WL Tso, GC Yeh, WS Lee, H Tseng, LC Chen, YS Ho Molecular Carcinogenesis: Published in cooperation with the University of …, 2006 | 39 | 2006 |
Differential toxicity of ataxin-3 isoforms in Drosophila models of Spinocerebellar Ataxia Type 3 SL Johnson, JR Blount, K Libohova, B Ranxhi, HL Paulson, WL Tsou, ... Neurobiology of disease 132, 104535, 2019 | 30 | 2019 |
Splice isoform-specific suppression of the Cav2. 1 variant underlying spinocerebellar ataxia type 6 WL Tsou, BW Soong, HL Paulson, E Rodríguez-Lebrón Neurobiology of disease 43 (3), 533-542, 2011 | 30 | 2011 |
Ubiquitin-interacting motifs of ataxin-3 regulate its polyglutamine toxicity through Hsc70-4-dependent aggregation SL Johnson, B Ranxhi, K Libohova, WL Tsou, SV Todi Elife 9, e60742, 2020 | 24 | 2020 |
Polyglutamine length-dependent toxicity from α1ACT in Drosophila models of spinocerebellar ataxia type 6 WL Tsou, SH Qiblawi, RR Hosking, CM Gomez, SV Todi Biology Open 5 (12), 1770-1775, 2016 | 24 | 2016 |
USP5 is dispensable for monoubiquitin maintenance in Drosophila G Ristic, WL Tsou, E Guzi, AJ Kanack, KM Scaglione, SV Todi Journal of Biological Chemistry 291 (17), 9161-9172, 2016 | 22 | 2016 |
A survey of protein interactions and posttranslational modifications that influence the polyglutamine diseases SL Johnson, WL Tsou, MV Prifti, AL Harris, SV Todi Frontiers in Molecular Neuroscience 15, 974167, 2022 | 14 | 2022 |
Targeting the VCP-binding motif of ataxin-3 improves phenotypes in Drosophila models of Spinocerebellar Ataxia Type 3 SL Johnson, K Libohova, JR Blount, AL Sujkowski, MV Prifti, WL Tsou, ... Neurobiology of disease 160, 105516, 2021 | 11 | 2021 |
Drosophila as a Model of Unconventional Translation in Spinocerebellar Ataxia Type 3 SL Johnson, MV Prifti, A Sujkowski, K Libohova, JR Blount, L Hong, ... Cells 11 (7), 1223, 2022 | 9 | 2022 |
Degron capability of the hydrophobic C‐terminus of the polyglutamine disease protein, ataxin‐3 JR Blount, SL Johnson, K Libohova, SV Todi, WL Tsou Journal of neuroscience research 98 (10), 2096-2108, 2020 | 5 | 2020 |