| Host–microbe interactions have shaped the genetic architecture of inflammatory bowel disease L Jostins, S Ripke, RK Weersma, RH Duerr, DP McGovern, KY Hui, ... Nature 491 (7422), 119-124, 2012 | 5368 | 2012 |
| Genome-wide meta-analysis increases to 71 the number of confirmed Crohn's disease susceptibility loci A Franke, DPB McGovern, JC Barrett, K Wang, GL Radford-Smith, ... Nature genetics 42 (12), 1118-1125, 2010 | 3211 | 2010 |
| Genetic risk and a primary role for cell-mediated immune mechanisms in multiple sclerosis Nature 476 (7359), 214-219, 2011 | 3050 | 2011 |
| Association analyses identify 38 susceptibility loci for inflammatory bowel disease and highlight shared genetic risk across populations JZ Liu, S Van Sommeren, H Huang, SC Ng, R Alberts, A Takahashi, ... Nature genetics 47 (9), 979-986, 2015 | 2660 | 2015 |
| A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1 J Hampe, A Franke, P Rosenstiel, A Till, M Teuber, K Huse, M Albrecht, ... Nature genetics 39 (2), 207-211, 2007 | 2371 | 2007 |
| Genomewide association study of severe Covid-19 with respiratory failure Severe Covid-19 GWAS Group New England Journal of Medicine 383 (16), 1522-1534, 2020 | 1995 | 2020 |
| Microbial exposure during early life has persistent effects on natural killer T cell function T Olszak, D An, S Zeissig, MP Vera, J Richter, A Franke, JN Glickman, ... Science 336 (6080), 489-493, 2012 | 1895 | 2012 |
| Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 CA Anderson, G Boucher, CW Lees, A Franke, M D'Amato, KD Taylor, ... Nature genetics 43 (3), 246-252, 2011 | 1757 | 2011 |
| Genome-wide scan reveals association of psoriasis with IL-23 and NF-κB pathways RP Nair, KC Duffin, C Helms, J Ding, PE Stuart, D Goldgar, ... Nature genetics 41 (2), 199-204, 2009 | 1651 | 2009 |
| XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease A Kaser, AH Lee, A Franke, JN Glickman, S Zeissig, H Tilg, ... Cell 134 (5), 743-756, 2008 | 1624 | 2008 |
| Analysis of immune-related loci identifies 48 new susceptibility variants for multiple sclerosis International IBD Genetics Consortium (IIBDGC), C Agliardi, L Alfredsson, ... Nature genetics 45 (11), 1353-1360, 2013 | 1371 | 2013 |
| New loci associated with kidney function and chronic kidney disease A Köttgen, C Pattaro, CA Böger, C Fuchsberger, M Olden, NL Glazer, ... Nature genetics 42 (5), 376-384, 2010 | 1367* | 2010 |
| Large-scale association analyses identify host factors influencing human gut microbiome composition A Kurilshikov, C Medina-Gomez, R Bacigalupe, D Radjabzadeh, J Wang, ... Nature genetics 53 (2), 156-165, 2021 | 1196 | 2021 |
| Identification of 15 new psoriasis susceptibility loci highlights the role of innate immunity LC Tsoi, SL Spain, J Knight, E Ellinghaus, PE Stuart, F Capon, J Ding, ... Nature genetics 44 (12), 1341-1348, 2012 | 1108 | 2012 |
| Deep resequencing of GWAS loci identifies independent rare variants associated with inflammatory bowel disease MA Rivas, M Beaudoin, A Gardet, C Stevens, Y Sharma, CK Zhang, ... Nature genetics 43 (11), 1066-1073, 2011 | 900 | 2011 |
| Autosomal dominant immune dysregulation syndrome in humans with CTLA4 mutations D Schubert, C Bode, R Kenefeck, TZ Hou, JB Wing, A Kennedy, ... Nature medicine 20 (12), 1410-1416, 2014 | 896 | 2014 |
| The dynamic genome of Hydra JA Chapman, EF Kirkness, O Simakov, SE Hampson, T Mitros, ... Nature 464 (7288), 592-596, 2010 | 896 | 2010 |
| Inherited determinants of Crohn's disease and ulcerative colitis phenotypes: a genetic association study I Cleynen, G Boucher, L Jostins, LP Schumm, S Zeissig, T Ahmad, ... The Lancet 387 (10014), 156-167, 2016 | 877 | 2016 |
| Mapping the human genetic architecture of COVID-19 Writing group Writing group leaders Pathak Gita A. 6 Andrews Shea J. 7 Kanai ... Nature 600 (7889), 472-477, 2021 | 804 | 2021 |
| Analysis of five chronic inflammatory diseases identifies 27 new associations and highlights disease-specific patterns at shared loci D Ellinghaus, L Jostins, SL Spain, A Cortes, J Bethune, B Han, YR Park, ... Nature genetics 48 (5), 510-518, 2016 | 776 | 2016 |
Michael NothnagelProfessor of Statistical Genetics / Bioinformatics, University of CologneGeverifieerd e-mailadres voor uni-koeln.de
