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Oscar Brück
Oscar Brück
Helsinki University Hospital, Comprehensive Cancer Center, Department of Hematology
Geverifieerd e-mailadres voor helsinki.fi - Homepage
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Increased proportion of mature NK cells is associated with successful imatinib discontinuation in chronic myeloid leukemia
M Ilander, U Olsson-Strömberg, H Schlums, J Guilhot, O Brück, ...
Leukemia 31 (5), 1108-1116, 2017
2582017
Immunogenomic landscape of hematological malignancies
O Dufva, P Pölönen, O Brück, MAI Keränen, J Klievink, J Mehtonen, ...
Cancer Cell 38 (3), 380-399. e13, 2020
1712020
Phenotype-based drug screening reveals association between venetoclax response and differentiation stage in acute myeloid leukemia
H Kuusanmäki, AM Leppä, P Pölönen, M Kontro, O Dufva, D Deb, ...
Haematologica 105 (3), 708, 2019
1522019
Implementing a functional precision medicine tumor board for acute myeloid leukemia
D Malani, A Kumar, O Brück, M Kontro, B Yadav, M Hellesøy, ...
Cancer discovery 12 (2), 388-401, 2022
1172022
Immune cell constitution in the tumor microenvironment predicts the outcome in diffuse large B-cell lymphoma
M Autio, SK Leivonen, O Brück, S Mustjoki, JM Jørgensen, ...
Haematologica 106 (3), 718, 2020
1162020
Immune cell contexture in the bone marrow tumor microenvironment impacts therapy response in CML
O Brück, S Blom, O Dufva, R Turkki, H Chheda, A Ribeiro, P Kovanen, ...
Leukemia 32 (7), 1643-1656, 2018
992018
PD-L1+ tumor-associated macrophages and PD-1+ tumor-infiltrating lymphocytes predict survival in primary testicular lymphoma
M Pollari, O Brück, T Pellinen, P Vähämurto, ML Karjalainen-Lindsberg, ...
haematologica 103 (11), 1908, 2018
832018
Somatic STAT3 mutations in Felty syndrome: an implication for a common pathogenesis with large granular lymphocyte leukemia
P Savola, O Brück, T Olson, T Kelkka, MJ Kauppi, PE Kovanen, S Kytölä, ...
haematologica 103 (2), 304, 2018
772018
Immune cell constitution in bone marrow microenvironment predicts outcome in adult ALL
H Hohtari, O Brück, S Blom, R Turkki, M Sinisalo, PE Kovanen, ...
Leukemia 33 (7), 1570-1582, 2019
612019
Somatic mutations in lymphocytes in patients with immune-mediated aplastic anemia
S Lundgren, MAI Keränen, M Kankainen, J Huuhtanen, G Walldin, ...
Leukemia 35 (5), 1365-1379, 2021
602021
Immune profiles in acute myeloid leukemia bone marrow associate with patient age, T-cell receptor clonality, and survival
O Brück, O Dufva, H Hohtari, S Blom, R Turkki, M Ilander, P Kovanen, ...
Blood advances 4 (2), 274-286, 2020
582020
Lumican is upregulated in osteoarthritis and contributes to TLR4-induced pro-inflammatory activation of cartilage degradation and macrophage polarization
G Barreto, B Senturk, L Colombo, O Brück, P Neidenbach, G Salzmann, ...
Osteoarthritis and cartilage 28 (1), 92-101, 2020
582020
T-cell inflamed tumor microenvironment predicts favorable prognosis in primary testicular lymphoma
SK Leivonen, M Pollari, O Brück, T Pellinen, M Autio, ...
haematologica 104 (2), 338, 2018
532018
The multimodality cell segmentation challenge: toward universal solutions
J Ma, R Xie, S Ayyadhury, C Ge, A Gupta, R Gupta, S Gu, Y Zhang, G Lee, ...
Nature methods, 1-11, 2024
522024
Dasatinib reversibly disrupts endothelial vascular integrity by increasing non-muscle myosin II contractility in a ROCK-dependent manner
A Kreutzman, B Colom-Fernández, AM Jiménez, M Ilander, ...
Clinical Cancer Research 23 (21), 6697-6707, 2017
482017
Characterization of polydactyly chondrocytes and their use in cartilage engineering
E Cavalli, C Levinson, M Hertl, N Broguiere, O Brück, S Mustjoki, ...
Scientific reports 9 (1), 4275, 2019
472019
Single-cell characterization of anti–LAG-3 and anti–PD-1 combination treatment in patients with melanoma
J Huuhtanen, H Kasanen, K Peltola, T Lönnberg, V Glumoff, O Brück, ...
The Journal of Clinical Investigation 133 (6), 2023
442023
Machine learning of bone marrow histopathology identifies genetic and clinical determinants in patients with MDS
OE Brück, SE Lallukka-Brück, HR Hohtari, A Ianevski, FT Ebeling, ...
Blood cancer discovery 2 (3), 238-249, 2021
432021
Prognostic impact of tumor-associated macrophages on survival is checkpoint dependent in classical Hodgkin lymphoma
K Karihtala, SK Leivonen, O Brück, ML Karjalainen-Lindsberg, S Mustjoki, ...
Cancers 12 (4), 877, 2020
402020
Clinical impact of immune cells and their spatial interactions in diffuse large B-cell lymphoma microenvironment
M Autio, SK Leivonen, O Brück, ML Karjalainen-Lindsberg, T Pellinen, ...
Clinical Cancer Research 28 (4), 781-792, 2022
382022
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