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Helen Heslop
Helen Heslop
Center for Cell and Gene Therapy, Baylor College of Medicine, Houston Methodist Hospital and Texas
Geverifieerd e-mailadres voor bcm.edu
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Hematology E-Book: Basic Principles and Practice
R Hoffman, EJ Benz, LE Silberstein, H Heslop, J Weitz, ME Salama, ...
Elsevier Health Sciences, 2022
17292022
Inducible apoptosis as a safety switch for adoptive cell therapy
A Di Stasi, SK Tey, G Dotti, Y Fujita, A Kennedy-Nasser, C Martinez, ...
New England Journal of Medicine 365 (18), 1673-1683, 2011
16702011
Virus-specific T cells engineered to coexpress tumor-specific receptors: persistence and antitumor activity in individuals with neuroblastoma
MA Pule, B Savoldo, GD Myers, C Rossig, HV Russell, G Dotti, MH Huls, ...
Nature medicine 14 (11), 1264-1270, 2008
13952008
Use of gene-modified virus-specific T lymphocytes to control Epstein-Barr-virus-related lymphoproliferation
CM Rooney, CYC Ng, S Loftin, CA Smith, C Li, RA Krance, MK Brenner, ...
The Lancet 345 (8941), 9-13, 1995
13841995
Infusion of cytotoxic T cells for the prevention and treatment of Epstein-Barr virus–induced lymphoma in allogeneic transplant recipients
CM Rooney, CA Smith, CYC Ng, SK Loftin, JW Sixbey, Y Gan, ...
Blood, The Journal of the American Society of Hematology 92 (5), 1549-1555, 1998
13661998
Antitumor activity and long-term fate of chimeric antigen receptor–positive T cells in patients with neuroblastoma
CU Louis, B Savoldo, G Dotti, M Pule, E Yvon, GD Myers, C Rossig, ...
Blood, The Journal of the American Society of Hematology 118 (23), 6050-6056, 2011
13532011
CD28 costimulation improves expansion and persistence of chimeric antigen receptor–modified T cells in lymphoma patients
B Savoldo, CA Ramos, E Liu, MP Mims, MJ Keating, G Carrum, ...
The Journal of clinical investigation 121 (5), 1822-1826, 2011
12662011
Human epidermal growth factor receptor 2 (HER2)–specific chimeric antigen receptor–modified T cells for the immunotherapy of HER2-positive sarcoma
N Ahmed, VS Brawley, M Hegde, C Robertson, A Ghazi, C Gerken, E Liu, ...
Journal of clinical oncology 33 (15), 1688-1696, 2015
10622015
Long–term restoration of immunity against Epstein–Barr virus infection by adoptive transfer of gene–modified virus–specific T lymphocytes
HE Heslop, CYC Ng, C Li, CA Smith, SK Loftin, RA Krance, MK Brenner, ...
Nature medicine 2 (5), 551-555, 1996
10301996
Long-term outcome of EBV-specific T-cell infusions to prevent or treat EBV-related lymphoproliferative disease in transplant recipients
HE Heslop, KS Slobod, MA Pule, GA Hale, A Rousseau, CA Smith, ...
Blood, The Journal of the American Society of Hematology 115 (5), 925-935, 2010
9252010
An inducible caspase 9 safety switch for T-cell therapy
KC Straathof, MA Pule, P Yotnda, G Dotti, EF Vanin, MK Brenner, ...
Blood 105 (11), 4247-4254, 2005
8322005
Closely related T-memory stem cells correlate with in vivo expansion of CAR. CD19-T cells and are preserved by IL-7 and IL-15
Y Xu, M Zhang, CA Ramos, A Durett, E Liu, O Dakhova, H Liu, ...
Blood, The Journal of the American Society of Hematology 123 (24), 3750-3759, 2014
7962014
HER2-specific chimeric antigen receptor–modified virus-specific T cells for progressive glioblastoma: a phase 1 dose-escalation trial
N Ahmed, V Brawley, M Hegde, K Bielamowicz, M Kalra, D Landi, ...
JAMA oncology 3 (8), 1094-1101, 2017
7922017
Engineering CD19-specific T lymphocytes with interleukin-15 and a suicide gene to enhance their anti-lymphoma/leukemia effects and safety
V Hoyos, B Savoldo, C Quintarelli, A Mahendravada, M Zhang, J Vera, ...
Leukemia 24 (6), 1160-1170, 2010
6522010
Monoculture-derived T lymphocytes specific for multiple viruses expand and produce clinically relevant effects in immunocompromised individuals
AM Leen, GD Myers, U Sili, MH Huls, H Weiss, KS Leung, G Carrum, ...
Nature medicine 12 (10), 1160-1166, 2006
6432006
Infusion of donor-derived CD19-redirected virus-specific T cells for B-cell malignancies relapsed after allogeneic stem cell transplant: a phase 1 study
CRY Cruz, KP Micklethwaite, B Savoldo, CA Ramos, S Lam, S Ku, ...
Blood, The Journal of the American Society of Hematology 122 (17), 2965-2973, 2013
6112013
Multicenter study of banked third-party virus-specific T cells to treat severe viral infections after hematopoietic stem cell transplantation
AM Leen, CM Bollard, AM Mendizabal, EJ Shpall, P Szabolcs, JH Antin, ...
Blood, The Journal of the American Society of Hematology 121 (26), 5113-5123, 2013
6102013
T lymphocytes coexpressing CCR4 and a chimeric antigen receptor targeting CD30 have improved homing and antitumor activity in a Hodgkin tumor model
A Di Stasi, B De Angelis, CM Rooney, L Zhang, A Mahendravada, ...
Blood, The Journal of the American Society of Hematology 113 (25), 6392-6402, 2009
6022009
A chimeric T cell antigen receptor that augments cytokine release and supports clonal expansion of primary human T cells
MA Pulè, KC Straathof, G Dotti, HE Heslop, CM Rooney, MK Brenner
Molecular Therapy 12 (5), 933-941, 2005
6002005
Post-transplant lymphoproliferative disorders
S Gottschalk, CM Rooney, HE Heslop
Annu. Rev. Med. 56 (1), 29-44, 2005
5562005
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