Recombinant human interleukin 5 is a selective activator of human eosinophil function. AF Lopez, CJ Sanderson, JR Gamble, HD Campbell, IG Young, ... The Journal of experimental medicine 167 (1), 219-224, 1988 | 1196 | 1988 |
Recombinant human granulocyte-macrophage colony-stimulating factor stimulates in vitro mature human neutrophil and eosinophil function, surface receptor expression, and survival. AF Lopez, DJ Williamson, JR Gamble, CG Begley, JM Harlan, ... The Journal of clinical investigation 78 (5), 1220-1228, 1986 | 867 | 1986 |
Monoclonal antibody-mediated targeting of CD123, IL-3 receptor α chain, eliminates human acute myeloid leukemic stem cells L Jin, EM Lee, HS Ramshaw, SJ Busfield, AG Peoppl, L Wilkinson, ... Cell stem cell 5 (1), 31-42, 2009 | 656 | 2009 |
Biologic properties in vitro of a recombinant human granulocyte-macrophage colony-stimulating factor D Metcalf, CG Begley, GR Johnson, NA Nicola, MA Vadas, AF Lopez, ... | 582 | 1986 |
Regulation of neutrophil apoptosis by tumor necrosis factor-α: requirement for TNFR55 and TNFR75 for induction of apoptosis in vitro J Murray, JAJ Barbara, SA Dunkley, AF Lopez, X Van Ostade, ... Blood, The Journal of the American Society of Hematology 90 (7), 2772-2783, 1997 | 408 | 1997 |
Effects of purified bacterially synthesized murine multi-CSF (IL-3) on hematopoiesis in normal adult mice D Metcalf, CG Begley, GR Johnson, NA Nicola, AF Lopez, DJ Williamson | 398 | 1986 |
The structure of the GM-CSF receptor complex reveals a distinct mode of cytokine receptor activation G Hansen, TR Hercus, BJ McClure, FC Stomski, M Dottore, J Powell, ... Cell 134 (3), 496-507, 2008 | 365 | 2008 |
TLR7 gain-of-function genetic variation causes human lupus GJ Brown, PF Cañete, H Wang, A Medhavy, J Bones, JA Roco, Y He, ... Nature 605 (7909), 349-356, 2022 | 361 | 2022 |
The granulocyte-macrophage colony-stimulating factor receptor: linking its structure to cell signaling and its role in disease TR Hercus, D Thomas, MA Guthridge, PG Ekert, J King-Scott, MW Parker, ... Blood, The Journal of the American Society of Hematology 114 (7), 1289-1298, 2009 | 355 | 2009 |
Purified colony-stimulating factors enhance the survival of human neutrophils and eosinophils in vitro: a rapid and sensitive microassay for colony-stimulating factors CG Begley, AF Lopez, NA Nicola, DJ Warren, MA Vadas, CJ Sanderson, ... | 354 | 1986 |
Peripheral T-cell lymphomas: initial features, natural history, and prognostic factors in a series of 174 patients diagnosed according to the REAL Classification A Lopez-Guillermo, J Cid, A Salar, A Lopez, C Montalban, JM Castrillo, ... Annals of Oncology 9 (8), 849-855, 1998 | 347 | 1998 |
Autocrine production and action of IL-3 and granulocyte colony-stimulating factor in chronic myeloid leukemia X Jiang, A Lopez, T Holyoake, A Eaves, C Eaves Proceedings of the National Academy of Sciences 96 (22), 12804-12809, 1999 | 317 | 1999 |
Purification and properties of bacterially synthesized human granulocyte-macrophage colony stimulating factor AW Burgess, CG Begley, GR Johnson, AF Lopez, DJ Williamson, ... | 293 | 1987 |
Targeting of acute myeloid leukaemia by cytokine‐induced killer cells redirected with a novel CD 123‐specific chimeric antigen receptor S Tettamanti, V Marin, I Pizzitola, CF Magnani, GMP Giordano Attianese, ... British journal of haematology 161 (3), 389-401, 2013 | 277 | 2013 |
Mechanism of activation of the GM-CSF, IL-3, and IL-5 family of receptors MA Guthridge, FC Stomski, D Thomas, JM Woodcock, CJ Bagley, ... Stem cells 16 (5), 301-313, 1998 | 266 | 1998 |
The GM–CSF/IL‐3/IL‐5 cytokine receptor family: from ligand recognition to initiation of signaling SE Broughton, U Dhagat, TR Hercus, TL Nero, MA Grimbaldeston, ... Immunological reviews 250 (1), 277-302, 2012 | 262 | 2012 |
The structural and functional basis of cytokine receptor activation: lessons from the common β subunit of the granulocyte-macrophage colony-stimulating factor, Interleukin-3 … CJ Bagley, JM Woodcock, FC Stomski, AF Lopez Blood, The Journal of the American Society of Hematology 89 (5), 1471-1482, 1997 | 259 | 1997 |
Stimulation of proliferation, differentiation, and function of human cells by primate interleukin 3. AF Lopez, LB To, YC Yang, JR Gamble, MF Shannon, GF Burns, ... Proceedings of the National Academy of Sciences 84 (9), 2761-2765, 1987 | 252 | 1987 |
Murine eosinophil differentiation factor. An eosinophil-specific colony-stimulating factor with activity for human cells. AF Lopez, CG Begley, DJ Williamson, DJ Warren, MA Vadas, ... The Journal of experimental medicine 163 (5), 1085-1099, 1986 | 252 | 1986 |
Activation of granulocyte cytotoxic function by purified mouse colony-stimulating factors. AF Lopez, NA Nicola, AW Burgess, D Metcalf, FL Battye, WA Sewell, ... Journal of Immunology (Baltimore, Md.: 1950) 131 (6), 2983-2988, 1983 | 246 | 1983 |