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Nilkanth Patel
Nilkanth Patel
NVIDIA | Ex. Takeda California | Molecular & Computational Biology, USC
usc.edu의 이메일 확인됨
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Synthon-based ligand discovery in virtual libraries of over 11 billion compounds
AA Sadybekov, AV Sadybekov, Y Liu, C Iliopoulos-Tsoutsouvas, ...
Nature 601 (7893), 452-459, 2022
2762022
Structural basis for selectivity and diversity in angiotensin II receptors
H Zhang, GW Han, A Batyuk, A Ishchenko, KL White, N Patel, ...
Nature 544 (7650), 327-332, 2017
2382017
Structural basis for ligand recognition and functional selectivity at angiotensin receptor*♦
H Zhang, H Unal, R Desnoyer, GW Han, N Patel, V Katritch, SS Karnik, ...
Journal of Biological Chemistry 290 (49), 29127-29139, 2015
1982015
Structural basis of ligand recognition at the human MT1 melatonin receptor
B Stauch, LC Johansson, JD McCorvy, N Patel, GW Han, XP Huang, ...
Nature 569 (7755), 284-288, 2019
1962019
Structural connection between activation microswitch and allosteric sodium site in GPCR signaling
KL White, MT Eddy, ZG Gao, GW Han, T Lian, A Deary, N Patel, ...
Structure 26 (2), 259-269. e5, 2018
1562018
XFEL structures of the human MT2 melatonin receptor reveal the basis of subtype selectivity
LC Johansson, B Stauch, JD McCorvy, GW Han, N Patel, XP Huang, ...
Nature 569 (7755), 289-292, 2019
1442019
Elucidating the active δ-opioid receptor crystal structure with peptide and small-molecule agonists
T Claff, J Yu, V Blais, N Patel, C Martin, L Wu, GW Han, BJ Holleran, ...
Science advances 5 (11), eaax9115, 2019
1082019
The importance of ligand-receptor conformational pairs in stabilization: spotlight on the N/OFQ G protein-coupled receptor
RL Miller, AA Thompson, C Trapella, R Guerrini, D Malfacini, N Patel, ...
Structure 23 (12), 2291-2299, 2015
902015
Structure-based mechanism of cysteinyl leukotriene receptor inhibition by antiasthmatic drugs
A Luginina, A Gusach, E Marin, A Mishin, R Brouillette, P Popov, ...
Science advances 5 (10), eaax2518, 2019
842019
Structural insights into the extracellular recognition of the human serotonin 2B receptor by an antibody
A Ishchenko, D Wacker, M Kapoor, A Zhang, GW Han, S Basu, N Patel, ...
Proceedings of the National Academy of Sciences 114 (31), 8223-8228, 2017
712017
Structural basis of ligand selectivity and disease mutations in cysteinyl leukotriene receptors
A Gusach, A Luginina, E Marin, RL Brouillette, É Besserer-Offroy, ...
Nature communications 10 (1), 5573, 2019
682019
Extrinsic Tryptophans as NMR Probes of Allosteric Coupling in Membrane Proteins: Application to the A2A Adenosine Receptor
MT Eddy, ZG Gao, P Mannes, N Patel, KA Jacobson, V Katritch, ...
Journal of the American Chemical Society 140 (26), 8228-8235, 2018
502018
Structure-based discovery of potent and selective melatonin receptor agonists
N Patel, XP Huang, JM Grandner, LC Johansson, B Stauch, JD McCorvy, ...
Elife 9, e53779, 2020
412020
Deep Learning for the Structure‐Based Binding Free Energy Prediction of Small Molecule Ligands
V Mysore, N Patel, A Ojewole
Computational Drug Discovery: Methods and Applications 1, 255-273, 2024
12024
Structural Studies of the Human Kappa Opioid Receptor Active State Conformations
MY Lee, N Patel, V Katritch, RC Stevens, V Cherezov
Biophysical Journal 110 (3), 38a-39a, 2016
12016
Melatonin receptor reveal the basis of subtype selectivity
LC Johansson, B Stauch, JD Mccorvy, GW Han, N Patel, XP Huang, ...
2019
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학술자료 1–16