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Daniel W Pack
Daniel W Pack
Professor, Chemical & Materials Engineering and Pharmaceutical Sciences, University of Kentucky
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Design and development of polymers for gene delivery
DW Pack, AS Hoffman, S Pun, PS Stayton
Nature reviews Drug discovery 4 (7), 581-593, 2005
31512005
Visual evidence of acidic environment within degrading poly (lactic-co-glycolic acid)(PLGA) microspheres
K Fu, DW Pack, AM Klibanov, R Langer
Pharmaceutical research 17, 100-106, 2000
9552000
Polymer-based gene delivery with low cytotoxicity by a unique balance of side-chain termini
D Putnam, CA Gentry, DW Pack, R Langer
Proceedings of the National Academy of Sciences 98 (3), 1200-1205, 2001
6642001
Microspheres for controlled release drug delivery
NK Varde, DW Pack
Expert opinion on biological therapy 4 (1), 35-51, 2004
5902004
A degradable polyethylenimine derivative with low toxicity for highly efficient gene delivery
ML Forrest, JT Koerber, DW Pack
Bioconjugate chemistry 14 (5), 934-940, 2003
5362003
Precise control of PLG microsphere size provides enhanced control of drug release rate
C Berkland, M King, A Cox, KK Kim, DW Pack
Journal of controlled release 82 (1), 137-147, 2002
5002002
Fabrication of PLG microspheres with precisely controlled and monodisperse size distributions
C Berkland, KK Kim, DW Pack
Journal of controlled release 73 (1), 59-74, 2001
4692001
Mathematical modeling of drug delivery from autocatalytically degradable PLGA microspheres—A review
ANF Versypt, DW Pack, RD Braatz
Journal of controlled release 165 (1), 29-37, 2013
3952013
PLGA microspheres containing plasmid DNA: preservation of supercoiled DNA via cryopreparation and carbohydrate stabilization
S Ando, D Putnam, DW Pack, R Langer
Journal of pharmaceutical sciences 88 (1), 126-130, 1999
3741999
Design of imidazole‐containing endosomolytic biopolymers for gene delivery
DW Pack, D Putnam, R Langer
Biotechnology and Bioengineering 67 (2), 217-223, 2000
3672000
Acetylation of polyethylenimine enhances gene delivery via weakened polymer/DNA interactions
NP Gabrielson, DW Pack
Biomacromolecules 7 (8), 2427-2435, 2006
3272006
Partial Acetylation of Polyethylenimine Enhances In Vitro Gene Delivery
ML Forrest, GE Meister, JT Koerber, DW Pack
Pharmaceutical research 21, 365-371, 2004
3092004
Microsphere size, precipitation kinetics and drug distribution control drug release from biodegradable polyanhydride microspheres
C Berkland, MJ Kipper, B Narasimhan, KK Kim, DW Pack
Journal of Controlled Release 94 (1), 129-141, 2004
2872004
PLG microsphere size controls drug release rate through several competing factors
C Berkland, K Kim, DW Pack
Pharmaceutical research 20, 1055-1062, 2003
2852003
Modeling small-molecule release from PLG microspheres: effects of polymer degradation and nonuniform drug distribution
C Raman, C Berkland, KK Kim, DW Pack
Journal of Controlled Release 103 (1), 149-158, 2005
2602005
Efficient polyethylenimine-mediated gene delivery proceeds via a caveolar pathway in HeLa cells
NP Gabrielson, DW Pack
Journal of Controlled Release 136 (1), 54-61, 2009
2542009
Microparticles
K Kim, DW Pack, C Berkland
US Patent 6,669,961, 2003
2312003
Microspheres for drug delivery
KK Kim, DW Pack
BioMEMS and Biomedical Nanotechnology: Volume I Biological and Biomedical …, 2006
2252006
Degradable self-assembling dendrons for gene delivery: experimental and theoretical insights into the barriers to cellular uptake
A Barnard, P Posocco, S Pricl, M Calderon, R Haag, ME Hwang, ...
Journal of the American Chemical Society 133 (50), 20288-20300, 2011
2032011
Controlling surface nano-structure using flow-limited field-injection electrostatic spraying (FFESS) of poly (D, L-lactide-co-glycolide)
C Berkland, DW Pack, KK Kim
Biomaterials 25 (25), 5649-5658, 2004
1982004
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