Triptolide suppresses IDH1-mutated malignancy via Nrf2-driven glutathione metabolism D Yu, Y Liu, Y Zhou, V Ruiz-Rodado, M Larion, G Xu, C Yang Proceedings of the National Academy of Sciences 117 (18), 9964-9972, 2020 | 114 | 2020 |
Targeting glycolysis through inhibition of lactate dehydrogenase impairs tumor growth in preclinical models of Ewing sarcoma C Yeung, AE Gibson, SH Issaq, N Oshima, JT Baumgart, LD Edessa, ... Cancer research 79 (19), 5060-5073, 2019 | 108 | 2019 |
Glutaminase-1 (GLS1) inhibition limits metastatic progression in osteosarcoma L Ren, V Ruiz-Rodado, T Dowdy, S Huang, SH Issaq, J Beck, H Wang, ... Cancer & metabolism 8, 1-13, 2020 | 89 | 2020 |
A fuzzy genetic programming-based algorithm for subgroup discovery and the application to one problem of pathogenesis of acute sore throat conditions in humans CJ Carmona, V Ruiz-Rodado, MJ del Jesús, A Weber, M Grootveld, ... Information Sciences 298, 180-197, 2015 | 65 | 2015 |
IDH1 Mutations Induce Organelle Defects Via Dysregulated Phospholipids A Lita, A Pliss, A Kuzmin, T Yamasaki, L Zhang, T Dowdy, C Burks, ... Nature communications, 2021 | 57 | 2021 |
Metabolic Reprogramming Associated with Aggressiveness Occurs in the G-CIMP-High Molecular Subtypes of IDH1mut Lower Grade Gliomas V Ruiz-Rodado, TM Malta, T Seki, A Lita, T Dowdy, O Celiku, ... Neuro-oncology, 2019 | 41 | 2019 |
Detection, monitoring and deleterious health effects of lipid oxidation products generated in culinary oils during thermal stressing episodes M Grootveld, V Ruiz-Rodado, C Silwood Inform, Magazine of the American Oil Chemists' Society 25 (10), 614-624, 2014 | 40 | 2014 |
Advances in measuring cancer cell metabolism with subcellular resolution V Ruiz-Rodado, A Lita, M Larion Nature Methods 19 (9), 1048-1063, 2022 | 33 | 2022 |
Detection of metabolic changes induced via drug treatments in live cancer cells and tissue using Raman imaging microscopy M Larion, T Dowdy, V Ruiz-Rodado, MW Meyer, H Song, W Zhang, ... Biosensors 9 (1), 5, 2018 | 31 | 2018 |
NMR analysis reveals significant differences in the plasma metabolic profiles of Niemann Pick C1 patients, heterozygous carriers, and healthy controls F Probert, V Ruiz-Rodado, D te Vruchte, ER Nicoli, TDW Claridge, ... Scientific Reports 7, 2017 | 29 | 2017 |
Magnetic resonance spectroscopy for the study of cns malignancies V Ruiz-Rodado, JR Brender, MK Cherukuri, MR Gilbert, M Larion Progress in Nuclear Magnetic Resonance Spectroscopy 122, 23-41, 2021 | 28 | 2021 |
Metabolic plasticity of IDH1-mutant glioma cell lines is responsible for low sensitivity to glutaminase inhibition V Ruiz-Rodado, A Lita, T Dowdy, O Celiku, AC Saldana, H Wang, ... Cancer & metabolism 8, 1-14, 2020 | 24 | 2020 |
Sphingolipid Pathway as a Source of Vulnerability in IDH1mut Glioma T Dowdy, L Zhang, O Celiku, S Movva, A Lita, V Ruiz-Rodado, MR Gilbert, ... Cancers 12 (10), 2910, 2020 | 22 | 2020 |
1H NMR-based metabolomics reveals neurochemical alterations in the brain of adolescent rats following acute methylphenidate administration E Quansah, V Ruiz-Rodado, M Grootveld, F Probert, TSC Zetterström Neurochemistry international 108, 109-120, 2017 | 22 | 2017 |
A Multifactorial Comparison of Ternary Combinations of Essential Oils in Topical Preparations to Current Antibiotic Prescription Therapies for the Control of Acne Vulgaris … K Laird, L Owen, V Ruiz-Rodado, P Price, M Grootveld, RRJ Arroo Phytotherapy Research 31, 410-417, 2017 | 22 | 2017 |
1H NMR-Linked Metabolomics Analysis of Liver from a Mouse Model of NP-C1 Disease V Ruiz-Rodado, ER Nicoli, F Probert, DA Smith, L Morris, CA Wassif, ... Journal of proteome research 15 (10), 3511-3527, 2016 | 22 | 2016 |
Brain metastasis models: What should we aim to achieve better treatments? M Masmudi-Martín, L Zhu, M Sanchez-Navarro, N Priego, ... Advanced Drug Delivery Reviews 169, 79-99, 2021 | 21 | 2021 |
1H NMR-linked urinary metabolic profiling of Niemann-Pick class C1 (NPC1) disease: Identification of potential new biomarkers using correlated component regression (CCR) and … V Ruiz-Rodado, R Marcos Luque-Baena, D te Vruchte, F Probert, ... Current Metabolomics 2 (2), 88-121, 2014 | 21 | 2014 |
Gut microbiome and metabolome in a non-human primate model of chronic excessive alcohol drinking D Piacentino, S Grant-Beurmann, C Vizioli, X Li, CF Moore, ... Translational psychiatry 11 (1), 609, 2021 | 14 | 2021 |
Cysteine is a limiting factor for glioma proliferation and survival V Ruiz‐Rodado, T Dowdy, A Lita, T Kramp, M Zhang, J Jung, ... Molecular Oncology 16 (9), 1777-1794, 2022 | 12 | 2022 |