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Seth S. Margolis
Seth S. Margolis
Department of Biological Chemistry, The Johns Hopkins University School of Medicine
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Metabolic regulation of oocyte cell death through the CaMKII-mediated phosphorylation of caspase-2
LK Nutt, SS Margolis, M Jensen, CE Herman, WG Dunphy, JC Rathmell, ...
Cell 123 (1), 89-103, 2005
3002005
EphB-mediated degradation of the RhoA GEF Ephexin5 relieves a developmental brake on excitatory synapse formation
SS Margolis, J Salogiannis, DM Lipton, C Mandel-Brehm, ZP Wills, ...
Cell 143 (3), 442-455, 2010
2962010
Role for the PP2A/B56δ phosphatase in regulating 14-3-3 release from Cdc25 to control mitosis
SS Margolis, JA Perry, CM Forester, LK Nutt, Y Guo, MJ Jardim, ...
Cell 127 (4), 759-773, 2006
2632006
PP1 control of M phase entry exerted through 14‐3‐3‐regulated Cdc25 dephosphorylation
SS Margolis, S Walsh, DC Weiser, M Yoshida, S Shenolikar, S Kornbluth
The EMBO journal, 2003
2122003
Angelman syndrome
SS Margolis, GL Sell, MA Zbinden, LM Bird
Neurotherapeutics 12 (3), 641-650, 2015
1872015
C-terminal regions of the human telomerase catalytic subunit essential for in vivo enzyme activity
SSR Banik, C Guo, AC Smith, SS Margolis, DA Richardson, CA Tirado, ...
Molecular and cellular biology 22 (17), 6234-6246, 2002
1562002
A mammalian nervous-system-specific plasma membrane proteasome complex that modulates neuronal function
KV Ramachandran, SS Margolis
Nature structural & molecular biology 24 (4), 419-430, 2017
1372017
A role for PP1 in the Cdc2/Cyclin B–mediated positive feedback activation of Cdc25
SS Margolis, JA Perry, DH Weitzel, CD Freel, M Yoshida, TA Haystead, ...
Molecular biology of the cell 17 (4), 1779-1789, 2006
1232006
Metabolic control of oocyte apoptosis mediated by 14-3-3ζ-regulated dephosphorylation of caspase-2
LK Nutt, MR Buchakjian, E Gan, R Darbandi, SY Yoon, JQ Wu, ...
Developmental cell 16 (6), 856-866, 2009
1162009
Phosphorylation of the cyclin b1 cytoplasmic retention sequence by mitogen-activated protein kinase and Plx
S Walsh, SS Margolis, S Kornbluth
Molecular cancer research 1 (4), 280-289, 2003
892003
Activity-dependent degradation of the nascentome by the neuronal membrane proteasome
KV Ramachandran, JM Fu, TB Schaffer, CH Na, M Delannoy, SS Margolis
Molecular cell 71 (1), 169-177. e6, 2018
792018
Enhanced sensitivity to cytochrome c–induced apoptosis mediated by PHAPI in breast cancer cells
ZT Schafer, AB Parrish, KM Wright, SS Margolis, JR Marks, M Deshmukh, ...
Cancer research 66 (4), 2210-2218, 2006
762006
From UBE3A to Angelman syndrome: a substrate perspective
GL Sell, SS Margolis
Frontiers in neuroscience 9, 322, 2015
742015
A role for Cdc2-and PP2A-mediated regulation of Emi2 in the maintenance of CSF arrest
Q Wu, Y Guo, A Yamada, JA Perry, MZ Wang, M Araki, CD Freel, JJ Tung, ...
Current Biology 17 (3), 213-224, 2007
662007
Aven-dependent activation of ATM following DNA damage
JY Guo, A Yamada, T Kajino, JQ Wu, W Tang, CD Freel, J Feng, BN Chau, ...
Current Biology 18 (13), 933-942, 2008
632008
The proteasome and its role in the nervous system
F Türker, EK Cook, SS Margolis
Cell chemical biology 28 (7), 903-917, 2021
592021
Amelogenin phosphorylation regulates tooth enamel formation by stabilizing a transient amorphous mineral precursor
NY Shin, H Yamazaki, E Beniash, X Yang, SS Margolis, MK Pugach, ...
Journal of Biological Chemistry 295 (7), 1943-1959, 2020
592020
When the checkpoints have gone: insights into Cdc25 functional activation
SS Margolis, S Kornbluth
Cell Cycle 3 (4), 423-426, 2004
452004
A dual role for the RhoGEF Ephexin5 in regulation of dendritic spine outgrowth
AM Hamilton, JT Lambert, LK Parajuli, O Vivas, DK Park, IS Stein, ...
Molecular and Cellular Neuroscience 80, 66-74, 2017
222017
Reducing expression of synapse-restricting protein Ephexin5 ameliorates Alzheimer’s-like impairment in mice
GL Sell, TB Schaffer, SS Margolis
The Journal of Clinical Investigation 127 (5), 1646-1650, 2017
212017
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