Deep mutational scanning of SARS-CoV-2 receptor binding domain reveals constraints on folding and ACE2 binding TN Starr, AJ Greaney, SK Hilton, D Ellis, KHD Crawford, AS Dingens, ... cell 182 (5), 1295-1310. e20, 2020 | 1999 | 2020 |
Comprehensive mapping of mutations in the SARS-CoV-2 receptor-binding domain that affect recognition by polyclonal human plasma antibodies AJ Greaney, AN Loes, KHD Crawford, TN Starr, KD Malone, HY Chu, ... Cell host & microbe 29 (3), 463-476. e6, 2021 | 1271 | 2021 |
Complete mapping of mutations to the SARS-CoV-2 spike receptor-binding domain that escape antibody recognition AJ Greaney, TN Starr, P Gilchuk, SJ Zost, E Binshtein, AN Loes, SK Hilton, ... Cell host & microbe 29 (1), 44-57. e9, 2021 | 1123 | 2021 |
Protocol and reagents for pseudotyping lentiviral particles with SARS-CoV-2 spike protein for neutralization assays KHD Crawford, R Eguia, AS Dingens, AN Loes, KD Malone, CR Wolf, ... Viruses 12 (5), 513, 2020 | 779 | 2020 |
Neutralizing antibodies correlate with protection from SARS-CoV-2 in humans during a fishery vessel outbreak with a high attack rate A Addetia, KHD Crawford, A Dingens, H Zhu, P Roychoudhury, ML Huang, ... Journal of clinical microbiology 58 (11), 10.1128/jcm. 02107-20, 2020 | 628 | 2020 |
Spread of a SARS-CoV-2 variant through Europe in the summer of 2020 EB Hodcroft, M Zuber, S Nadeau, TG Vaughan, KHD Crawford, ... Nature 595 (7869), 707-712, 2021 | 616 | 2021 |
Dynamics of Neutralizing Antibody Titers in the Months After Severe Acute Respiratory Syndrome Coronavirus 2 Infection KHD Crawford, AS Dingens, R Eguia, CR Wolf, N Wilcox, JK Logue, ... The Journal of Infectious Diseases, 2020 | 318 | 2020 |
Antibodies elicited by mRNA-1273 vaccination bind more broadly to the receptor binding domain than do those from SARS-CoV-2 infection AJ Greaney, AN Loes, LE Gentles, KHD Crawford, TN Starr, KD Malone, ... Science translational medicine 13 (600), eabi9915, 2021 | 236 | 2021 |
Efficacy, durability, and response predictors of low-dose interleukin-2 therapy for chronic graft-versus-host disease J Koreth, HT Kim, KT Jones, PB Lange, CG Reynolds, MJ Chammas, ... Blood, The Journal of the American Society of Hematology 128 (1), 130-137, 2016 | 217 | 2016 |
A human coronavirus evolves antigenically to escape antibody immunity RT Eguia, KHD Crawford, T Stevens-Ayers, L Kelnhofer-Millevolte, ... PLoS pathogens 17 (4), e1009453, 2021 | 214 | 2021 |
A pseudovirus system enables deep mutational scanning of the full SARS-CoV-2 spike B Dadonaite, KHD Crawford, CE Radford, AG Farrell, CY Timothy, ... Cell 186 (6), 1263-1278. e20, 2023 | 97 | 2023 |
Serological identification of SARS-CoV-2 infections among children visiting a hospital during the initial Seattle outbreak AS Dingens, KHD Crawford, A Adler, SL Steele, K Lacombe, R Eguia, ... Nature communications 11 (1), 1-6, 2020 | 72 | 2020 |
Epitope profiling reveals binding signatures of SARS-CoV-2 immune response in natural infection and cross-reactivity with endemic human CoVs CI Stoddard, J Galloway, HY Chu, MM Shipley, K Sung, HL Itell, CR Wolf, ... Cell Reports 35 (8), 2021 | 54 | 2021 |
Identification of HIV gp41-specific antibodies that mediate killing of infected cells KL Williams, M Stumpf, NE Naiman, S Ding, M Garrett, T Gobillot, ... PLoS pathogens 15 (2), e1007572, 2019 | 45 | 2019 |
Attenuated influenza virions expressing the SARS-CoV-2 receptor-binding domain induce neutralizing antibodies in mice AN Loes, LE Gentles, AJ Greaney, KHD Crawford, JD Bloom Viruses 12 (9), 987, 2020 | 39 | 2020 |
Stabilization of the SARS-CoV-2 spike receptor-binding domain using deep mutational scanning and structure-based design D Ellis, N Brunette, KHD Crawford, AC Walls, MN Pham, C Chen, ... Frontiers in immunology 12, 710263, 2021 | 38 | 2021 |
Functional analysis of clinical response to low-dose IL-2 in patients with refractory chronic graft-versus-host disease JS Whangbo, HT Kim, S Nikiforow, J Koreth, AC Alho, B Falahee, S Kim, ... Blood advances 3 (7), 984-994, 2019 | 29 | 2019 |
alignparse: A Python package for parsing complex features from high-throughput long-read sequencing KHD Crawford, JD Bloom Journal of open source software 4 (44), 2019 | 27 | 2019 |
Phage-DMS: a comprehensive method for fine mapping of antibody epitopes ME Garrett, HL Itell, KHD Crawford, R Basom, JD Bloom, J Overbaugh IScience 23 (10), 2020 | 15 | 2020 |
Mapping the neutralizing specificity of human anti-HIV serum by deep mutational scanning CE Radford, P Schommers, L Gieselmann, KHD Crawford, B Dadonaite, ... Cell Host & Microbe 31 (7), 1200-1215. e9, 2023 | 14 | 2023 |