| Dependency of colorectal cancer on a TGF-β-driven program in stromal cells for metastasis initiation A Calon, E Espinet, S Palomo-Ponce, DVF Tauriello, M Iglesias, ... Cancer cell 22 (5), 571-584, 2012 | 1146 | 2012 |
| The intestinal stem cell signature identifies colorectal cancer stem cells and predicts disease relapse A Merlos-Suárez, FM Barriga, P Jung, M Iglesias, MV Céspedes, ... Cell stem cell 8 (5), 511-524, 2011 | 1093 | 2011 |
| Recombinant pharmaceuticals from microbial cells: a 2015 update L Sanchez-Garcia, L Martín, R Mangues, N Ferrer-Miralles, E Vázquez, ... Microbial cell factories 15, 1-7, 2016 | 406 | 2016 |
| K-ras and p16 Aberrations Confer Poor Prognosis in Human Colorectal Cancer M Esteller, S Gonzalez, RA Risques, E Marcuello, R Mangues, JR Germa, ... Journal of Clinical Oncology 19 (2), 299-304, 2001 | 339 | 2001 |
| K-ras Codon 12 Mutation Induces Higher Level of Resistance to Apoptosis and Predisposition to Anchorage-independent Growth Than Codon 13 Mutation or Proto … S Guerrero, I Casanova, L Farré, A Mazo, G Capellà, R Mangues Cancer research 60 (23), 6750-6756, 2000 | 318 | 2000 |
| Short amino acid stretches can mediate amyloid formation in globular proteins: the Src homology 3 (SH3) case S Ventura, J Zurdo, S Narayanan, M Parreño, R Mangues, B Reif, F Chiti, ... Proceedings of the National Academy of Sciences 101 (19), 7258-7263, 2004 | 296 | 2004 |
| Brain interleukin-1 beta in Alzheimer's disease and vascular dementia. R Cacabelos, XA Alvarez, L Fernandez-Novoa, A Franco, R Mangues, ... Methods and findings in experimental and clinical pharmacology 16 (2), 141-151, 1994 | 268 | 1994 |
| Orthotopic microinjection of human colon cancer cells in nude mice induces tumor foci in all clinically relevant metastatic sites MV Céspedes, C Espina, MA García-Cabezas, M Trias, A Boluda, ... The American journal of pathology 170 (3), 1077-1085, 2007 | 231 | 2007 |
| Mouse models in oncogenesis and cancer therapy MV Cespedes, I Casanova, M Parreño, R Mangues Clinical and Translational Oncology 8, 318-329, 2006 | 228 | 2006 |
| STC1 expression by cancer-associated fibroblasts drives metastasis of colorectal cancer C Pena, MV Céspedes, MB Lindh, S Kiflemariam, A Mezheyeuski, ... Cancer research 73 (4), 1287-1297, 2013 | 212 | 2013 |
| Colon cancer cells colonize the lung from established liver metastases through p38 MAPK signalling and PTHLH J Urosevic, X Garcia-Albeniz, E Planet, S Real, MV Céspedes, M Guiu, ... Nature cell biology 16 (7), 685-694, 2014 | 195 | 2014 |
| Antitumor Effect of a Farnesyl Protein Transferase Inhibitor in Mammary and Lymphoid Tumors Overexpressing N-ras in Transgenic Mice R Mangues, T Corral, NE Kohl, WF Symmans, S Lu, M Malumbres, ... Cancer research 58 (6), 1253-1259, 1998 | 181 | 1998 |
| uPA/uPAR and SERPINE1 in head and neck cancer: role in tumor resistance, metastasis, prognosis and therapy MA Pavón, I Arroyo-Solera, MV Céspedes, I Casanova, X León, ... Oncotarget 7 (35), 57351, 2016 | 160 | 2016 |
| K-ras codon-specific mutations produce distinctive metabolic phenotypes in human fibroblasts P Vizan, LG Boros, A Figueras, G Capella, R Mangues, S Bassilian, S Lim, ... Cancer research 65 (13), 5512-5515, 2005 | 134 | 2005 |
| Protein-based therapeutic killing for cancer therapies N Serna, L Sánchez-García, U Unzueta, R Díaz, E Vázquez, R Mangues, ... Trends in biotechnology 36 (3), 318-335, 2018 | 129 | 2018 |
| Intracellular CXCR4+ cell targeting with T22-empowered protein-only nanoparticles U Unzueta, MV Céspedes, N Ferrer-Miralles, I Casanova, J Cedano, ... International journal of nanomedicine, 4533-4544, 2012 | 124 | 2012 |
| In Vivo Architectonic Stability of Fully de Novo Designed Protein-Only Nanoparticles MV Céspedes, U Unzueta, W Tatkiewicz, A Sanchez-Chardi, ... ACS nano 8 (5), 4166-4176, 2014 | 101 | 2014 |
| K-ras Asp12 mutant neither interacts with Raf, nor signals through Erk and is less tumorigenic than K-ras Val12 MV Céspedes, FJ Sancho, S Guerrero, M Parreño, I Casanova, MA Pavón, ... Carcinogenesis 27 (11), 2190-2200, 2006 | 92 | 2006 |
| Inactivation of the cyclin-dependent kinase inhibitor p15INK4b by deletion and de novo methylation with independence of p16INK4a alterations in murine primary T-cell lymphomas M Malumbres, IP de Castro, J Santos, B Meléndez, R Mangues, ... Oncogene 14 (11), 1361-1370, 1997 | 89 | 1997 |
| A critical role for Rac1 in tumor progression of human colorectal adenocarcinoma cells C Espina, MV Céspedes, MA García-Cabezas, MTG del Pulgar, A Boluda, ... The American journal of pathology 172 (1), 156-166, 2008 | 88 | 2008 |