| Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 … T Shimada, H Yamazaki, M Mimura, Y Inui, FP Guengerich Journal of pharmacology and experimental therapeutics 270 (1), 414-423, 1994 | 3684 | 1994 |
| Membrane transporters in drug development Nature reviews Drug discovery 9 (3), 215-236, 2010 | 3609 | 2010 |
| The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature DR Nelson, T Kamataki, DJ Waxman, FP Guengerich, RW Estabrook, ... DNA and cell biology 12 (1), 1-51, 1993 | 2294 | 1993 |
| Common and uncommon cytochrome P450 reactions related to metabolism and chemical toxicity FP Guengerich Chemical research in toxicology 14 (6), 611-650, 2001 | 2202 | 2001 |
| Cytochrome p450 and chemical toxicology FP Guengerich Chemical research in toxicology 21 (1), 70-83, 2008 | 2061 | 2008 |
| The P450 superfamily: updated listing of all genes and recommended nomenclature for the chromosomal loci DW Nebert, DR Nelson, M Adesnik, MJ Coon, RW Estabrook, ... Dna 8 (1), 1-13, 1989 | 1897 | 1989 |
| Cytochrome P-450 3A4: regulation and role in drug metabolism FP Guengerich Annual review of pharmacology and toxicology 39 (1), 1-17, 1999 | 1611 | 1999 |
| Role of human cytochrome P-450 IIE1 in the oxidation of many low molecular weight cancer suspects FP Guengerich, DH Kim, M Iwasaki Chemical research in toxicology 4 (2), 168-179, 1991 | 1582 | 1991 |
| The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature DW NEBERT, DR NELSON, MJ COON, RW ESTABROOK, ... DNA and cell biology 10 (1), 1-14, 1991 | 1437 | 1991 |
| Oxidation of toxic and carcinogenic chemicals by human cytochrome P-450 enzymes FP Guengerich, T Shimada Chemical research in toxicology 4 (4), 391-407, 1991 | 1392 | 1991 |
| Purification and characterization of liver microsomal cytochromes P-450: electrophoretic, spectral, catalytic, and immunochemical properties and inducibility of eight isozymes … FP Guengerich, GA Dannan, ST Wright, MV Martin, LS Kaminsky Biochemistry 21 (23), 6019-6030, 1982 | 1328 | 1982 |
| Mapping the genetic architecture of gene expression in human liver EE Schadt, C Molony, E Chudin, K Hao, X Yang, PY Lum, A Kasarskis, ... PLoS biology 6 (5), e107, 2008 | 1204 | 2008 |
| Activation of chemically diverse procarcinogens by human cytochrome P-450 1B1 T Shimada, CL Hayes, H Yamazaki, S Amin, SS Hecht, FP Guengerich, ... Cancer research 56 (13), 2979-2984, 1996 | 1043 | 1996 |
| Characterization of rat and human liver microsomal cytochrome P-450 forms involved in nifedipine oxidation, a prototype for genetic polymorphism in oxidative drug metabolism. FP Guengerich, MV Martin, PH Beaune, P Kremers, T Wolff, DJ Waxman Journal of Biological Chemistry 261 (11), 5051-5060, 1986 | 991 | 1986 |
| Reactions and significance of cytochrome P-450 enzymes FP Guengerich Journal of Biological Chemistry 266 (16), 10019-10022, 1991 | 936 | 1991 |
| Human cytochrome P-450PA (P-450IA2), the phenacetin O-deethylase, is primarily responsible for the hepatic 3-demethylation of caffeine and N-oxidation of carcinogenic arylamines. MA Butler, M Iwasaki, FP Guengerich, FF Kadlubar Proceedings of the National Academy of Sciences 86 (20), 7696-7700, 1989 | 870 | 1989 |
| Cytochrome P450s and other enzymes in drug metabolism and toxicity FP Guengerich The AAPS journal 8, E101-E111, 2006 | 830 | 2006 |
| Chemical mechanisms of catalysis by cytochromes P-450: a unified view FP Guengerich, TL Macdonald Accounts of Chemical Research 17 (1), 9-16, 1984 | 818 | 1984 |
| Dealkylation of pentoxyresorufin: a rapid and sensitive assay for measuring induction of cytochrome (s) P-450 by phenobarbital and other xenobiotics in the rat RA Lubet, RT Mayer, JW Cameron, RW Nims, MD Burke, T Wolff, ... Archives of biochemistry and biophysics 238 (1), 43-48, 1985 | 781 | 1985 |
| Regulation of rat hepatic cytochrome P-450: age-dependent expression, hormonal imprinting, and xenobiotic inducibility of sex-specific isoenzymes DJ Waxman, GA Dannan, FP Guengerich Biochemistry 24 (16), 4409-4417, 1985 | 739 | 1985 |
Hiroshi Yamazaki昭和薬科大学教授ac.shoyaku.ac.jp의 이메일 확인됨