| Metabolic network structure determines key aspects of functionality and regulation J Stelling, S Klamt, K Bettenbrock, S Schuster, ED Gilles Nature 420 (6912), 190-193, 2002 | 1013 | 2002 |
| Structural and functional analysis of cellular networks with CellNetAnalyzer S Klamt, J Saez-Rodriguez, ED Gilles BMC systems biology 1, 1-13, 2007 | 661 | 2007 |
| Hypergraphs and cellular networks S Klamt, UU Haus, F Theis PLoS computational biology 5 (5), e1000385, 2009 | 608 | 2009 |
| Comparison of network-based pathway analysis methods JA Papin, J Stelling, ND Price, S Klamt, S Schuster, BO Palsson Trends in biotechnology 22 (8), 400-405, 2004 | 501 | 2004 |
| A methodology for the structural and functional analysis of signaling and regulatory networks S Klamt, J Saez-Rodriguez, JA Lindquist, L Simeoni, ED Gilles BMC bioinformatics 7, 1-26, 2006 | 493 | 2006 |
| Discrete logic modelling as a means to link protein signalling networks with functional analysis of mammalian signal transduction J Saez‐Rodriguez, LG Alexopoulos, J Epperlein, R Samaga, ... Molecular systems biology 5 (1), 331, 2009 | 410 | 2009 |
| A logical model provides insights into T cell receptor signaling J Saez-Rodriguez, L Simeoni, JA Lindquist, R Hemenway, U Bommhardt, ... PLoS computational biology 3 (8), e163, 2007 | 405 | 2007 |
| MEMOTE for standardized genome-scale metabolic model testing C Lieven, ME Beber, BG Olivier, FT Bergmann, M Ataman, P Babaei, ... Nature biotechnology 38 (3), 272-276, 2020 | 399 | 2020 |
| Two approaches for metabolic pathway analysis? S Klamt, J Stelling Trends in biotechnology 21 (2), 64-69, 2003 | 389 | 2003 |
| Minimal cut sets in biochemical reaction networks S Klamt, ED Gilles Bioinformatics 20 (2), 226-234, 2004 | 356 | 2004 |
| Computation of elementary modes: a unifying framework and the new binary approach J Gagneur, S Klamt BMC bioinformatics 5, 1-21, 2004 | 354 | 2004 |
| Combinatorial complexity of pathway analysis in metabolic networks S Klamt, J Stelling Molecular biology reports 29, 233-236, 2002 | 315 | 2002 |
| FluxAnalyzer: exploring structure, pathways, and flux distributions in metabolic networks on interactive flux maps S Klamt, J Stelling, M Ginkel, ED Gilles Bioinformatics 19 (2), 261-269, 2003 | 299 | 2003 |
| Transforming Boolean models to continuous models: methodology and application to T-cell receptor signaling DM Wittmann, J Krumsiek, J Saez-Rodriguez, DA Lauffenburger, S Klamt, ... BMC systems biology 3, 1-21, 2009 | 280 | 2009 |
| GSMN-TB: a web-based genome-scale network model of Mycobacterium tuberculosismetabolism DJV Beste, T Hooper, G Stewart, B Bonde, C Avignone-Rossa, ... Genome biology 8, 1-18, 2007 | 256 | 2007 |
| The logic of EGFR/ErbB signaling: theoretical properties and analysis of high-throughput data R Samaga, J Saez-Rodriguez, LG Alexopoulos, PK Sorger, S Klamt PLoS computational biology 5 (8), e1000438, 2009 | 240 | 2009 |
| SBML Level 3: an extensible format for the exchange and reuse of biological models SM Keating, D Waltemath, M König, F Zhang, A Dräger, C Chaouiya, ... Molecular systems biology 16 (8), e9110, 2020 | 236 | 2020 |
| SBML qualitative models: a model representation format and infrastructure to foster interactions between qualitative modelling formalisms and tools C Chaouiya, D Bérenguier, SM Keating, A Naldi, MP Van Iersel, ... BMC systems biology 7, 1-15, 2013 | 198 | 2013 |
| Model-based metabolic engineering enables high yield itaconic acid production by Escherichia coli BJ Harder, K Bettenbrock, S Klamt Metabolic engineering 38, 29-37, 2016 | 179 | 2016 |
| Calculability analysis in underdetermined metabolic networks illustrated by a model of the central metabolism in purple nonsulfur bacteria S Klamt, S Schuster, ED Gilles Biotechnology and bioengineering 77 (7), 734-751, 2002 | 162 | 2002 |
