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Mariona Graupera
Mariona Graupera
Group Leader of Vascular Biology and Signalling, Institut d’Investigacio biomèdica de Bellvitge
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The emerging mechanisms of isoform-specific PI3K signalling
B Vanhaesebroeck, J Guillermet-Guibert, M Graupera, B Bilanges
Nature reviews Molecular cell biology 11 (5), 329-341, 2010
20712010
Angiogenesis selectively requires the p110α isoform of PI3K to control endothelial cell migration
M Graupera, J Guillermet-Guibert, LC Foukas, LK Phng, RJ Cain, ...
Nature 453 (7195), 662-666, 2008
6222008
Simvastatin treatment improves liver sinusoidal endothelial dysfunction in CCl4 cirrhotic rats
JG Abraldes, A Rodríguez-Vilarrupla, M Graupera, C Zafra, ...
Journal of hepatology 46 (6), 1040-1046, 2007
2842007
cKit lineage hemogenic endothelium-derived cells contribute to mesenteric lymphatic vessels
L Stanczuk, I Martinez-Corral, MH Ulvmar, Y Zhang, B Laviña, M Fruttiger, ...
Cell reports 10 (10), 1708-1721, 2015
2612015
Targeting PI3K in cancer: impact on tumor cells, their protective stroma, angiogenesis, and immunotherapy
K Okkenhaug, M Graupera, B Vanhaesebroeck
Cancer discovery 6 (10), 1090-1105, 2016
2482016
The metabolic co-regulator PGC1α suppresses prostate cancer metastasis
V Torrano, L Valcarcel-Jimenez, AR Cortazar, X Liu, J Urosevic, ...
Nature cell biology 18 (6), 645-656, 2016
2172016
Cyclooxygenase-derived products modulate the increased intrahepatic resistance of cirrhotic rat livers
M Graupera, JC Garcıa-Pagán, JG Abraldes, C Peralta, M Bragulat, ...
Hepatology 37 (1), 172-181, 2003
2022003
Somatic activating mutations in Pik3ca cause sporadic venous malformations in mice and humans
SD Castillo, E Tzouanacou, M Zaw-Thin, IM Berenjeno, VER Parker, ...
Science translational medicine 8 (332), 332ra43-332ra43, 2016
1862016
Re-education of tumor-associated macrophages by CXCR2 blockade drives senescence and tumor inhibition in advanced prostate cancer
D Di Mitri, M Mirenda, J Vasilevska, A Calcinotto, N Delaleu, A Revandkar, ...
Cell reports 28 (8), 2156-2168. e5, 2019
1782019
PI3 kinase inhibition improves vascular malformations in mouse models of hereditary haemorrhagic telangiectasia
R Ola, A Dubrac, J Han, F Zhang, JS Fang, B Larrivée, M Lee, AA Urarte, ...
Nature communications 7 (1), 13650, 2016
1752016
Integrin-dependent and-independent functions of astrocytic fibronectin in retinal angiogenesis
D Stenzel, A Lundkvist, D Sauvaget, M Busse, M Graupera, ...
Development 138 (20), 4451-4463, 2011
1572011
Regulation of angiogenesis by PI3K signaling networks
M Graupera, M Potente
Experimental cell research 319 (9), 1348-1355, 2013
1422013
5-Lipoxygenase inhibition reduces intrahepatic vascular resistance of cirrhotic rat livers: a possible role of cysteinyl-leukotrienes
M Graupera, JC García–Pagán, E Titos, J Claria, A Massaguer, J Bosch, ...
Gastroenterology 122 (2), 387-393, 2002
1372002
Developmental and tumor angiogenesis requires the mitochondria-shaping protein Opa1
S Herkenne, O Ek, M Zamberlan, A Pellattiero, M Chergova, I Chivite, ...
Cell metabolism 31 (5), 987-1003. e8, 2020
1352020
Resistance to antiangiogenic therapies by metabolic symbiosis in renal cell carcinoma PDX models and patients
G Jiménez-Valerio, M Martínez-Lozano, N Bassani, A Vidal, ...
Cell reports 15 (6), 1134-1143, 2016
1192016
PTEN mediates Notch-dependent stalk cell arrest in angiogenesis
H Serra, I Chivite, A Angulo-Urarte, A Soler, JD Sutherland, ...
Nature communications 6 (1), 7935, 2015
1152015
Cyclooxygenase-1 inhibition corrects endothelial dysfunction in cirrhotic rat livers
M Graupera, JC Garcı́a-Pagán, M Parés, JG Abraldes, J Roselló, J Bosch, ...
Journal of hepatology 39 (4), 515-521, 2003
1042003
Metronomic chemotherapy following the maximum tolerated dose is an effective anti‐tumour therapy affecting angiogenesis, tumour dissemination and cancer stem cells
M Vives, MM Ginestà, K Gracova, M Graupera, O Casanovas, G Capellà, ...
International journal of cancer 133 (10), 2464-2472, 2013
1022013
Sinusoidal endothelial COX-1-derived prostanoids modulate the hepatic vascular tone of cirrhotic rat livers
M Graupera, S March, P Engel, J Rodés, J Bosch, JC Garcia-Pagan
American Journal of Physiology-Gastrointestinal and Liver Physiology 288 (4 …, 2005
982005
ALK1 loss results in vascular hyperplasia in mice and humans through PI3K activation
E Alsina-Sanchís, Y García-Ibáñez, AM Figueiredo, C Riera-Domingo, ...
Arteriosclerosis, Thrombosis, and Vascular Biology 38 (5), 1216-1229, 2018
972018
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