| Vascular endothelial growth factor receptor-1 modulates vascular endothelial growth factor-mediated angiogenesis via nitric oxide B Bussolati, C Dunk, M Grohman, CD Kontos, J Mason, A Ahmed The American journal of pathology 159 (3), 993-1008, 2001 | 374 | 2001 |
| PTEN modulates vascular endothelial growth factor-mediated signaling and angiogenic effects J Huang, CD Kontos Journal of Biological Chemistry 277 (13), 10760-10766, 2002 | 355 | 2002 |
| A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension S Liu, RT Premont, CD Kontos, S Zhu, DC Rockey Nature medicine 11 (9), 952-958, 2005 | 302 | 2005 |
| Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt CD Kontos, TP Stauffer, WP Yang, JD York, L Huang, MA Blanar, T Meyer, ... Molecular and cellular biology 18 (7), 4131-4140, 1998 | 301 | 1998 |
| IQGAP1, a novel vascular endothelial growth factor receptor binding protein, is involved in reactive oxygen species—dependent endothelial migration and proliferation M Yamaoka-Tojo, M Ushio-Fukai, L Hilenski, SI Dikalov, YE Chen, T Tojo, ... Circulation research 95 (3), 276-283, 2004 | 288 | 2004 |
| A systems biology perspective on sVEGFR1: its biological function, pathogenic role and therapeutic use FTH Wu, MO Stefanini, FM Gabhann, CD Kontos, BH Annex, AS Popel Journal of cellular and molecular medicine 14 (3), 528-552, 2010 | 278 | 2010 |
| Negative regulation of myofibroblast differentiation by PTEN (Phosphatase and Tensin Homolog Deleted on chromosome 10) ES White, RG Atrasz, B Hu, SH Phan, V Stambolic, TW Mak, ... American journal of respiratory and critical care medicine 173 (1), 112-121, 2006 | 275 | 2006 |
| Cadmium induction of reactive oxygen species activates the mTOR pathway, leading to neuronal cell death L Chen, B Xu, L Liu, Y Luo, H Zhou, W Chen, T Shen, X Han, CD Kontos, ... Free Radical Biology and Medicine 50 (5), 624-632, 2011 | 272 | 2011 |
| Impaired angiogenesis after hindlimb ischemia in type 2 diabetes mellitus: differential regulation of vascular endothelial growth factor receptor 1 and soluble vascular … S Hazarika, AO Dokun, Y Li, AS Popel, CD Kontos, BH Annex Circulation research 101 (9), 948-956, 2007 | 250 | 2007 |
| Endogenous S-nitrosothiols protect against myocardial injury B Lima, GKW Lam, L Xie, DL Diesen, N Villamizar, J Nienaber, E Messina, ... Proceedings of the National Academy of Sciences 106 (15), 6297-6302, 2009 | 245 | 2009 |
| Targeting VE-PTP activates TIE2 and stabilizes the ocular vasculature J Shen, M Frye, BL Lee, JL Reinardy, JM McClung, K Ding, M Kojima, ... The Journal of clinical investigation 124 (10), 4564-4576, 2014 | 238 | 2014 |
| Functional significance of Tie2 signaling in the adult vasculature KG Peters, CD Kontos, PC Lin, AL Wong, P Rao, L Huang, MW Dewhirst, ... Recent progress in hormone research 59 (1), 51-71, 2004 | 235 | 2004 |
| Inhibition of rat corneal angiogenesis by a nuclease-resistant RNA aptamer specific for angiopoietin-2 RR White, S Shan, CP Rusconi, G Shetty, MW Dewhirst, CD Kontos, ... Proceedings of the National Academy of Sciences 100 (9), 5028-5033, 2003 | 232 | 2003 |
| Expression of Tie2/Tek in breast tumour vasculature provides a new marker for evaluation of tumour angiogenesis KG Peters, A Coogan, D Berry, J Marks, JD Iglehart, CD Kontos, P Rao, ... British journal of cancer 77 (1), 51-56, 1998 | 212 | 1998 |
| PTEN as an effector in the signaling of antimigratory G protein-coupled receptor T Sanchez, S Thangada, MT Wu, CD Kontos, D Wu, H Wu, T Hla Proceedings of the National Academy of Sciences 102 (12), 4312-4317, 2005 | 204 | 2005 |
| Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein βγ subunit signaling to protein kinase B/Akt S Liu, RT Premont, CD Kontos, J Huang, DC Rockey Journal of Biological Chemistry 278 (50), 49929-49935, 2003 | 201 | 2003 |
| Activation of vascular endothelial growth factor receptor-1 sustains angiogenesis and Bcl-2 expression via the phosphatidylinositol 3-kinase pathway in endothelial cells J Cai, S Ahmad, WG Jiang, J Huang, CD Kontos, M Boulton, A Ahmed Diabetes 52 (12), 2959-2968, 2003 | 199 | 2003 |
| VEGF induces Tie2 shedding via a phosphoinositide 3-kinase/Akt–dependent pathway to modulate Tie2 signaling CM Findley, MJ Cudmore, A Ahmed, CD Kontos Arteriosclerosis, thrombosis, and vascular biology 27 (12), 2619-2626, 2007 | 197 | 2007 |
| Allelic and locus heterogeneity in inherited venous malformations JT Calvert, TJ Riney, CD Kontos, EH Cha, VG Prieto, CR Shea, JN Berg, ... Human molecular genetics 8 (7), 1279-1289, 1999 | 159 | 1999 |
| Inhibition of vascular smooth muscle cell proliferation, migration, and survival by the tumor suppressor protein PTEN J Huang, CD Kontos Arteriosclerosis, thrombosis, and vascular biology 22 (5), 745-751, 2002 | 153 | 2002 |
