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Juha T. Huiskonen
Juha T. Huiskonen
Professor of Structural Biology, University of Helsinki
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Localized reconstruction of subunits from electron cryomicroscopy images of macromolecular complexes
SL Ilca, A Kotecha, X Sun, MM Poranen, DI Stuart, JT Huiskonen
Nature communications 6 (1), 8843, 2015
2372015
Structure of the polycystic kidney disease TRP channel Polycystin-2 (PC2)
M Grieben, ACW Pike, CA Shintre, E Venturi, S El-Ajouz, A Tessitore, ...
Nature structural & molecular biology 24 (2), 114-122, 2017
2022017
Isolation and characterization of the positive-sense replicative intermediate of a negative-strand RNA virus
A York, N Hengrung, FT Vreede, JT Huiskonen, E Fodor
Proceedings of the National Academy of Sciences 110 (45), E4238-E4245, 2013
1762013
Electron cryotomography of Tula hantavirus suggests a unique assembly paradigm for enveloped viruses
JT Huiskonen, J Hepojoki, P Laurinmaki, A Vaheri, H Lankinen, ...
Journal of virology 84 (10), 4889-4897, 2010
1722010
Electron Cryo-Microscopy and Single-Particle Averaging of Rift Valley Fever Virus: Evidence for GN-GC Glycoprotein Heterodimers
JT Huiskonen, AK Overby, F Weber, K Grünewald
Journal of virology 83 (8), 3762-3769, 2009
1642009
Electron cryotomography of measles virus reveals how matrix protein coats the ribonucleocapsid within intact virions
L Liljeroos, JT Huiskonen, A Ora, P Susi, SJ Butcher
Proceedings of the National Academy of Sciences 108 (44), 18085-18090, 2011
1472011
The structural basis of lipid scrambling and inactivation in the endoplasmic reticulum scramblase TMEM16K
SR Bushell, ACW Pike, ME Falzone, NJG Rorsman, CM Ta, RA Corey, ...
Nature communications 10 (1), 3956, 2019
1412019
Structure of the bacteriophage ϕ6 nucleocapsid suggests a mechanism for sequential RNA packaging
JT Huiskonen, F de Haas, D Bubeck, DH Bamford, SD Fuller, SJ Butcher
Structure 14 (6), 1039-1048, 2006
1392006
Eisosome proteins assemble into a membrane scaffold
L Karotki, JT Huiskonen, CJ Stefan, NE Ziółkowska, R Roth, MA Surma, ...
Journal of Cell Biology 195 (5), 889-902, 2011
1362011
Insights into bunyavirus architecture from electron cryotomography of Uukuniemi virus
AK Överby, RF Pettersson, K Grünewald, JT Huiskonen
Proceedings of the National Academy of Sciences 105 (7), 2375-2379, 2008
1362008
Molecular insights into lipid-assisted Ca2+ regulation of the TRP channel Polycystin-2
M Wilkes, MG Madej, L Kreuter, D Rhinow, V Heinz, S De Sanctis, ...
Nature structural & molecular biology 24 (2), 123-130, 2017
1352017
Acidic pH-induced conformations and LAMP1 binding of the Lassa virus glycoprotein spike
S Li, Z Sun, R Pryce, ML Parsy, SK Fehling, K Schlie, CA Siebert, ...
PLoS pathogens 12 (2), e1005418, 2016
1332016
Near-atomic structure of Japanese encephalitis virus reveals critical determinants of virulence and stability
X Wang, SH Li, L Zhu, QG Nian, S Yuan, Q Gao, Z Hu, Q Ye, XF Li, DY Xie, ...
Nature communications 8 (1), 14, 2017
1262017
Structure of the Lassa virus glycan shield provides a model for immunological resistance
Y Watanabe, J Raghwani, JD Allen, GE Seabright, S Li, F Moser, ...
Proceedings of the National Academy of Sciences 115 (28), 7320-7325, 2018
1172018
Structure-based energetics of protein interfaces guides foot-and-mouth disease virus vaccine design
A Kotecha, J Seago, K Scott, A Burman, S Loureiro, J Ren, C Porta, ...
Nature structural & molecular biology 22 (10), 788-794, 2015
1152015
Minor proteins, mobile arms and membrane–capsid interactions in the bacteriophage PRD1 capsid
C San Martín, JT Huiskonen, JKH Bamford, SJ Butcher, SD Fuller, ...
nature structural biology 9 (10), 756-763, 2002
1062002
Structure of a phleboviral envelope glycoprotein reveals a consolidated model of membrane fusion
S Halldorsson, AJ Behrens, K Harlos, JT Huiskonen, RM Elliott, M Crispin, ...
Proceedings of the National Academy of Sciences 113 (26), 7154-7159, 2016
1052016
Shielding and activation of a viral membrane fusion protein
S Halldorsson, S Li, M Li, K Harlos, TA Bowden, JT Huiskonen
Nature communications 9 (1), 349, 2018
1012018
Efficient production of Rift Valley fever virus-like particles: the antiviral protein MxA can inhibit primary transcription of bunyaviruses
M Habjan, N Penski, V Wagner, M Spiegel, AK Överby, G Kochs, ...
Virology 385 (2), 400-408, 2009
1002009
Nucleocapsid assembly in pneumoviruses is regulated by conformational switching of the N protein
M Renner, M Bertinelli, C Leyrat, GC Paesen, LF Saraiva de Oliveira, ...
Elife 5, e12627, 2016
952016
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