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Yu Zong Chen
Yu Zong Chen
Professor Department of Pharmacy National University of Singapore Verified email at nus.edu.sg
sz.tsinghua.edu.cn의 이메일 확인됨
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Mechanisms of drug combinations: interaction and network perspectives
J Jia, F Zhu, X Ma, ZW Cao, YX Li, YZ Chen
Nature reviews Drug discovery 8 (2), 111-128, 2009
10162009
TTD: therapeutic target database
X Chen, ZL Ji, YZ Chen
Nucleic acids research 30 (1), 412-415, 2002
7832002
SVM-Prot: web-based support vector machine software for functional classification of a protein from its primary sequence
CZ Cai, LY Han, ZL Ji, X Chen, YZ Chen
Nucleic acids research 31 (13), 3692-3697, 2003
7512003
Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery
F Zhu, Z Shi, C Qin, L Tao, X Liu, F Xu, L Zhang, Y Song, X Liu, J Zhang, ...
Nucleic acids research 40 (D1), D1128-D1136, 2012
5442012
Therapeutic target database update 2018: enriched resource for facilitating bench-to-clinic research of targeted therapeutics
YH Li, CY Yu, XX Li, P Zhang, J Tang, Q Yang, T Fu, X Zhang, X Cui, G Tu, ...
Nucleic acids research 46 (D1), D1121-D1127, 2018
5342018
Ligand–protein inverse docking and its potential use in the computer search of protein targets of a small molecule
YZ Chen, DG Zhi
Proteins: Structure, Function, and Bioinformatics 43 (2), 217-226, 2001
4832001
PROFEAT: a web server for computing structural and physicochemical features of proteins and peptides from amino acid sequence
ZR Li, HH Lin, LY Han, L Jiang, X Chen, YZ Chen
Nucleic acids research 34 (suppl_2), W32-W37, 2006
3872006
NOREVA: normalization and evaluation of MS-based metabolomics data
B Li, J Tang, Q Yang, S Li, X Cui, Y Li, Y Chen, W Xue, X Li, F Zhu
Nucleic acids research 45 (W1), W162-W170, 2017
3622017
HIT: linking herbal active ingredients to targets
H Ye, L Ye, H Kang, D Zhang, L Tao, K Tang, X Liu, R Zhu, Q Liu, ...
Nucleic acids research 39 (suppl_1), D1055-D1059, 2010
3432010
Update of TTD: therapeutic target database
F Zhu, BC Han, P Kumar, XH Liu, XH Ma, XN Wei, L Huang, YF Guo, ...
Nucleic acids research 38 (suppl_1), D787-D791, 2010
3272010
Clustered patterns of species origins of nature-derived drugs and clues for future bioprospecting
F Zhu, C Qin, L Tao, X Liu, Z Shi, X Ma, J Jia, Y Tan, C Cui, J Lin, C Tan, ...
Proceedings of the National Academy of Sciences 108 (31), 12943-12948, 2011
3002011
Therapeutic target database update 2016: enriched resource for bench to clinical drug target and targeted pathway information
H Yang, C Qin, YH Li, L Tao, J Zhou, CY Yu, F Xu, Z Chen, F Zhu, ...
Nucleic acids research 44 (D1), D1069-D1074, 2016
2902016
What contributes to serotonin–norepinephrine reuptake inhibitors’ dual-targeting mechanism? The key role of transmembrane domain 6 in human serotonin and norepinephrine …
W Xue, F Yang, P Wang, G Zheng, Y Chen, X Yao, F Zhu
ACS Chemical Neuroscience 9 (5), 1128-1140, 2018
2552018
Enzyme family classification by support vector machines
CZ Cai, LY Han, ZL Ji, YZ Chen
Proteins: Structure, Function, and Bioinformatics 55 (1), 66-76, 2004
2422004
Database of traditional Chinese medicine and its application to studies of mechanism and to prescription validation
X Chen, H Zhou, YB Liu, JF Wang, H Li, CY Ung, LY Han, ZW Cao, ...
British journal of pharmacology 149 (8), 1092-1103, 2006
2312006
Prediction of P-glycoprotein substrates by a support vector machine approach
Y Xue, CW Yap, LZ Sun, ZW Cao, JF Wang, YZ Chen
Journal of chemical information and computer sciences 44 (4), 1497-1505, 2004
2282004
Therapeutic targets: progress of their exploration and investigation of their characteristics
CJ Zheng, LY Han, CW Yap, ZL Ji, ZW Cao, YZ Chen
Pharmacological reviews 58 (2), 259-279, 2006
2262006
NPASS: natural product activity and species source database for natural product research, discovery and tool development
X Zeng, P Zhang, W He, C Qin, S Chen, L Tao, Y Wang, Y Tan, D Gao, ...
Nucleic acids research 46 (D1), D1217-D1222, 2018
2252018
Effect of molecular descriptor feature selection in support vector machine classification of pharmacokinetic and toxicological properties of chemical agents
Y Xue, ZR Li, CW Yap, LZ Sun, X Chen, YZ Chen
Journal of chemical information and computer sciences 44 (5), 1630-1638, 2004
2112004
Effect of selection of molecular descriptors on the prediction of blood− brain barrier penetrating and nonpenetrating agents by statistical learning methods
H Li, CW Yap, CY Ung, Y Xue, ZW Cao, YZ Chen
Journal of Chemical Information and Modeling 45 (5), 1376-1384, 2005
2032005
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