| Tumor necrosis factor-α induces neurotoxicity via glutamate release from hemichannels of activated microglia in an autocrine manner H Takeuchi, S Jin, J Wang, G Zhang, J Kawanokuchi, R Kuno, Y Sonobe, ... Journal of Biological Chemistry 281 (30), 21362-21368, 2006 | 901 | 2006 |
| Long-read sequencing identifies GGC repeat expansions in NOTCH2NLC associated with neuronal intranuclear inclusion disease J Sone, S Mitsuhashi, A Fujita, T Mizuguchi, K Hamanaka, K Mori, H Koike, ... Nature genetics 51 (8), 1215-1221, 2019 | 442 | 2019 |
| Differential expression of inflammation‐and apoptosis‐related genes in spinal cords of a mutant SOD1 transgenic mouse model of familial amyotrophic lateral sclerosis T Yoshihara, S Ishigaki, M Yamamoto, Y Liang, Jun, I Niwa, H Takeuchi, ... Journal of neurochemistry 80 (1), 158-167, 2002 | 350 | 2002 |
| Interleukin-1β induces blood–brain barrier disruption by downregulating sonic hedgehog in astrocytes Y Wang, S Jin, Y Sonobe, Y Cheng, H Horiuchi, B Parajuli, ... PloS one 9 (10), e110024, 2014 | 330 | 2014 |
| Production and functions of IL-17 in microglia J Kawanokuchi, K Shimizu, A Nitta, K Yamada, T Mizuno, H Takeuchi, ... Journal of neuroimmunology 194 (1-2), 54-61, 2008 | 320 | 2008 |
| Gene expression profile of spinal motor neurons in sporadic amyotrophic lateral sclerosis YM Jiang, M Yamamoto, Y Kobayashi, T Yoshihara, Y Liang, S Terao, ... Annals of neurology 57 (2), 236-251, 2005 | 317 | 2005 |
| Neuritic beading induced by activated microglia is an early feature of neuronal dysfunction toward neuronal death by inhibition of mitochondrial respiration and axonal transport H Takeuchi, T Mizuno, G Zhang, J Wang, J Kawanokuchi, R Kuno, ... Journal of Biological Chemistry 280 (11), 10444-10454, 2005 | 315 | 2005 |
| Autocrine activation of microglia by tumor necrosis factor-α R Kuno, J Wang, J Kawanokuchi, H Takeuchi, T Mizuno, A Suzumura Journal of neuroimmunology 162 (1-2), 89-96, 2005 | 264 | 2005 |
| Production and functions of IL-33 in the central nervous system S Yasuoka, J Kawanokuchi, B Parajuli, S Jin, Y Doi, M Noda, Y Sonobe, ... Brain research 1385, 8-17, 2011 | 244 | 2011 |
| Fingolimod phosphate promotes the neuroprotective effects of microglia H Noda, H Takeuchi, T Mizuno, A Suzumura Journal of neuroimmunology 256 (1-2), 13-18, 2013 | 242 | 2013 |
| Interferon‐γ directly induces neurotoxicity through a neuron specific, calcium‐permeable complex of IFN‐γ receptor and AMPA GluRl receptor T Mizuno, G Zhang, H Takeuchi, J Kawanokuchi, J Wang, Y Sonobe, S Jin, ... The FASEB Journal 22 (6), 1797-1806, 2008 | 219 | 2008 |
| Interleukin-34 selectively enhances the neuroprotective effects of microglia to attenuate oligomeric amyloid-β neurotoxicity T Mizuno, Y Doi, H Mizoguchi, S Jin, M Noda, Y Sonobe, H Takeuchi, ... The American journal of pathology 179 (4), 2016-2027, 2011 | 183 | 2011 |
| Blockade of gap junction hemichannel suppresses disease progression in mouse models of amyotrophic lateral sclerosis and Alzheimer's disease H Takeuchi, H Mizoguchi, Y Doi, S Jin, M Noda, J Liang, H Li, Y Zhou, ... PloS one 6 (6), e21108, 2011 | 181 | 2011 |
| Fractalkine attenuates excito-neurotoxicity via microglial clearance of damaged neurons and antioxidant enzyme heme oxygenase-1 expression M Noda, Y Doi, J Liang, J Kawanokuchi, Y Sonobe, H Takeuchi, T Mizuno, ... Journal of Biological Chemistry 286 (3), 2308-2319, 2011 | 178 | 2011 |
| GM-CSF increases LPS-induced production of proinflammatory mediators via upregulation of TLR4 and CD14 in murine microglia B Parajuli, Y Sonobe, J Kawanokuchi, Y Doi, M Noda, H Takeuchi, ... Journal of neuroinflammation 9, 1-12, 2012 | 176 | 2012 |
| Mitochondrial localization of mutant superoxide dismutase 1 triggers caspase-dependent cell death in a cellular model of familial amyotrophic lateral sclerosis H Takeuchi, Y Kobayashi, S Ishigaki, M Doyu, G Sobue Journal of biological chemistry 277 (52), 50966-50972, 2002 | 173 | 2002 |
| Conditioned medium from the stem cells of human dental pulp improves cognitive function in a mouse model of Alzheimer’s disease T Mita, Y Furukawa-Hibi, H Takeuchi, H Hattori, K Yamada, H Hibi, ... Behavioural Brain Research 293, 189-197, 2015 | 171 | 2015 |
| The radical scavenger edaravone prevents oxidative neurotoxicity induced by peroxynitrite and activated microglia M Banno, T Mizuno, H Kato, G Zhang, J Kawanokuchi, J Wang, R Kuno, ... Neuropharmacology 48 (2), 283-290, 2005 | 168 | 2005 |
| CCL11 enhances excitotoxic neuronal death by producing reactive oxygen species in microglia B Parajuli, H Horiuchi, T Mizuno, H Takeuchi, A Suzumura Glia 63 (12), 2274-2284, 2015 | 156 | 2015 |
| Microglia activated with the toll-like receptor 9 ligand CpG attenuate oligomeric amyloid β neurotoxicity in in vitro and in vivo models of Alzheimer’s disease Y Doi, T Mizuno, Y Maki, S Jin, H Mizoguchi, M Ikeyama, M Doi, ... The American journal of pathology 175 (5), 2121-2132, 2009 | 155 | 2009 |