| Genetic and pharmacologic inactivation of ANGPTL3 and cardiovascular disease FE Dewey, V Gusarova, RL Dunbar, C O’Dushlaine, C Schurmann, ... New England Journal of Medicine 377 (3), 211-221, 2017 | 841 | 2017 |
| Establishment of a general NAFLD scoring system for rodent models and comparison to human liver pathology W Liang, AL Menke, A Driessen, GH Koek, JH Lindeman, R Stoop, ... PloS one 9 (12), e115922, 2014 | 606 | 2014 |
| Alirocumab inhibits atherosclerosis, improves the plaque morphology, and enhances the effects of a statin [S] S Kühnast, JWA van der Hoorn, EJ Pieterman, AM van den Hoek, ... Journal of lipid research 55 (10), 2103-2112, 2014 | 250 | 2014 |
| Metformin lowers plasma triglycerides by promoting VLDL-triglyceride clearance by brown adipose tissue in mice JJ Geerling, MR Boon, GC van der Zon, SAA van den Berg, ... Diabetes 63 (3), 880-891, 2014 | 203 | 2014 |
| Time-resolved and tissue-specific systems analysis of the pathogenesis of insulin resistance R Kleemann, M van Erk, L Verschuren, AM van den Hoek, M Koek, ... PloS one 5 (1), e8817, 2010 | 181 | 2010 |
| Intracerebroventricular administration of neuropeptide Y induces hepatic insulin resistance via sympathetic innervation AM Van Den Hoek, C van Heijningen, JP Schroder-van der Elst, ... Diabetes 57 (9), 2304-2310, 2008 | 164 | 2008 |
| Intracerebroventricular neuropeptide Y infusion precludes inhibition of glucose and VLDL production by insulin AM van den Hoek, PJ Voshol, BN Karnekamp, RM Buijs, JA Romijn, ... Diabetes 53 (10), 2529-2534, 2004 | 148 | 2004 |
| PYY3–36 reinforces insulin action on glucose disposal in mice fed a high-fat diet AM Van Den Hoek, AC Heijboer, EPM Corssmit, PJ Voshol, JA Romijn, ... Diabetes 53 (8), 1949-1952, 2004 | 147 | 2004 |
| Peripheral cannabinoid 1 receptor blockade activates brown adipose tissue and diminishes dyslipidemia and obesity MR Boon, S Kooijman, AD Van Dam, LR Pelgrom, JFP Berbée, ... The FASEB Journal 28 (12), 5361-5375, 2014 | 129 | 2014 |
| Ghrelin differentially affects hepatic and peripheral insulin sensitivity in mice AC Heijboer, AM van den Hoek, ET Parlevliet, LM Havekes, JA Romijn, ... Diabetologia 49, 732-738, 2006 | 126 | 2006 |
| Gut–brain axis: regulation of glucose metabolism AC Heijboer, H Pijl, AM Van den Hoek, LM Havekes, JA Romijn, ... Journal of neuroendocrinology 18 (12), 883-894, 2006 | 116 | 2006 |
| Chronic PYY3–36 treatment promotes fat oxidation and ameliorates insulin resistance in C57BL6 mice AM Van Den Hoek, AC Heijboer, PJ Voshol, LM Havekes, JA Romijn, ... American Journal of Physiology-Endocrinology and Metabolism 292 (1), E238-E245, 2007 | 109 | 2007 |
| Metabolically induced liver inflammation leads to NASH and differs from LPS-or IL-1β-induced chronic inflammation W Liang, JH Lindeman, AL Menke, DP Koonen, M Morrison, LM Havekes, ... Laboratory investigation 94 (5), 491-502, 2014 | 94 | 2014 |
| APOE* 3Leiden. CETP transgenic mice as model for pharmaceutical treatment of the metabolic syndrome AM van den Hoek, JWA van der Hoorn, AC Maas, RM Van den Hoogen, ... Diabetes, Obesity and Metabolism 16 (6), 537-544, 2014 | 72 | 2014 |
| Uncovering a predictive molecular signature for the onset of NASH-related fibrosis in a translational NASH mouse model A van Koppen, L Verschuren, AM van den Hoek, J Verheij, MC Morrison, ... Cellular and molecular gastroenterology and hepatology 5 (1), 83-98. e10, 2018 | 66 | 2018 |
| Obeticholic acid modulates serum metabolites and gene signatures characteristic of human NASH and attenuates inflammation and fibrosis progression in Ldlr‐/‐. leiden mice MC Morrison, L Verschuren, K Salic, J Verheij, A Menke, PY Wielinga, ... Hepatology Communications 2 (12), 1513-1532, 2018 | 61 | 2018 |
| Intracerebroventricular administration of melanotan II increases insulin sensitivity of glucose disposal in mice AC Heijboer, AM Van Den Hoek, H Pijl, PJ Voshol, LM Havekes, ... Diabetologia 48, 1621-1626, 2005 | 59 | 2005 |
| The CCR2 inhibitor propagermanium attenuates diet-induced insulin resistance, adipose tissue inflammation and non-alcoholic steatohepatitis P Mulder, AM van den Hoek, R Kleemann PloS one 12 (1), e0169740, 2017 | 57 | 2017 |
| Salsalate activates brown adipose tissue in mice AD Van Dam, KJ Nahon, S Kooijman, SM Van Den Berg, AA Kanhai, ... Diabetes 64 (5), 1544-1554, 2015 | 54 | 2015 |
| Overexpression of APOC1 in obob mice leads to hepatic steatosis and severe hepatic insulin resistance M Muurling, AM van den Hoek, RP Mensink, H Pijl, JA Romijn, ... Journal of lipid research 45 (1), 9-16, 2004 | 54 | 2004 |
