Genome-wide association analyses identify new risk variants and the genetic architecture of amyotrophic lateral sclerosis W Van Rheenen, A Shatunov, AM Dekker, RL McLaughlin, FP Diekstra, ... Nature genetics 48 (9), 1043-1048, 2016 | 634 | 2016 |
Haploinsufficiency leads to neurodegeneration in C9ORF72 ALS/FTD human induced motor neurons Y Shi, S Lin, KA Staats, Y Li, WH Chang, ST Hung, E Hendricks, ... Nature medicine 24 (3), 313-325, 2018 | 628 | 2018 |
EPHA4 is a disease modifier of amyotrophic lateral sclerosis in animal models and in humans A Van Hoecke, L Schoonaert, R Lemmens, M Timmers, KA Staats, ... Nature medicine 18 (9), 1418-1422, 2012 | 366 | 2012 |
Oligodendrocyte dysfunction in the pathogenesis of amyotrophic lateral sclerosis T Philips, A Bento-Abreu, A Nonneman, W Haeck, K Staats, V Geelen, ... Brain 136 (2), 471-482, 2013 | 303 | 2013 |
The microRNA-29 family dictates the balance between homeostatic and pathological glucose handling in diabetes and obesity J Dooley, JE Garcia-Perez, J Sreenivasan, SM Schlenner, ... Diabetes 65 (1), 53-61, 2016 | 167 | 2016 |
Elongator subunit 3 (ELP3) modifies ALS through tRNA modification A Bento-Abreu, G Jager, B Swinnen, L Rué, S Hendrickx, A Jones, ... Human molecular genetics 27 (7), 1276-1289, 2018 | 91 | 2018 |
ADAR2 mislocalization and widespread RNA editing aberrations in C9orf72-mediated ALS/FTD S Moore, E Alsop, I Lorenzini, A Starr, BE Rabichow, E Mendez, JL Levy, ... Acta neuropathologica 138, 49-65, 2019 | 78 | 2019 |
Rapamycin increases survival in ALS mice lacking mature lymphocytes KA Staats, S Hernandez, S Schönefeldt, A Bento-Abreu, J Dooley, ... Molecular neurodegeneration 8, 1-5, 2013 | 76 | 2013 |
Blood-based biomarkers of inflammation in amyotrophic lateral sclerosis KA Staats, DR Borchelt, MG Tansey, J Wymer Molecular Neurodegeneration 17 (1), 11, 2022 | 64 | 2022 |
Identification and therapeutic rescue of autophagosome and glutamate receptor defects in C9ORF72 and sporadic ALS neurons Y Shi, ST Hung, G Rocha, S Lin, GR Linares, KA Staats, C Seah, Y Wang, ... JCI insight 4 (15), e127736, 2019 | 63 | 2019 |
Olmsted syndrome: exploration of the immunological phenotype D Danso-Abeam, J Zhang, J Dooley, KA Staats, L Van Eyck, ... Orphanet journal of rare diseases 8, 1-8, 2013 | 62 | 2013 |
Astrocytes in amyotrophic lateral sclerosis: direct effects on motor neuron survival KA Staats, L Van Den Bosch Journal of biological physics 35 (4), 337-346, 2009 | 62 | 2009 |
The multifaceted role of kinases in amyotrophic lateral sclerosis: genetic, pathological and therapeutic implications W Guo, T Vandoorne, J Steyaert, KA Staats, L Van Den Bosch Brain 143 (6), 1651-1673, 2020 | 50 | 2020 |
Dupuytren's disease susceptibility gene, EPDR1, is involved in myofibroblast contractility. KA Staats, T Wu, BS Gan, DB O'Gorman, RA Ophoff Journal of Dermatological Sciences 83 (2), 131-137, 2016 | 34 | 2016 |
Genome-wide burden of deleterious coding variants increased in schizophrenia DYJ Loohuis LM, Vorstman JA, Ori AP, Staats KA, Wang T, Richards AL ... Nature Communications 6 (7501), 2015 | 34 | 2015 |
PARALS Registry; SLALOM Group; SLAP Registry; FALS Sequencing Consortium; SLAGEN Consortium; NNIPPS Study Group. Genome-wide association analyses identify new risk variants and … W van Rheenen, A Shatunov, AM Dekker, RL McLaughlin, FP Diekstra, ... Nat Genet 48 (9), 1043-1048, 2016 | 29 | 2016 |
Aire mediates thymic expression and tolerance of pancreatic antigens via an unconventional transcriptional mechanism D Danso‐Abeam, KA Staats, D Franckaert, L Van Den Bosch, A Liston, ... European journal of immunology 43 (1), 75-84, 2013 | 29 | 2013 |
Genetic ablation of IP3 receptor 2 increases cytokines and decreases survival of SOD1G93A mice KA Staats, S Humblet-Baron, A Bento-Abreu, W Scheveneels, A Nikolaou, ... Human molecular genetics 25 (16), 3491-3499, 2016 | 27 | 2016 |
Beta-2 microglobulin is important for disease progression in a murine model for amyotrophic lateral sclerosis KA Staats, S Schönefeldt, M Van Rillaer, A Van Hoecke, P Van Damme, ... Frontiers in Cellular Neuroscience 7, 249, 2013 | 26 | 2013 |
Genetic ablation of phospholipase C delta 1 increases survival in SOD1G93A mice KA Staats, L Van Helleputte, AR Jones, A Bento-Abreu, A Van Hoecke, ... Neurobiology of Disease 60, 11-17, 2013 | 24 | 2013 |