Induction of mitochondrial dysfunction as a strategy for targeting tumour cells in metabolically compromised microenvironments X Zhang, M Fryknäs, E Hernlund, W Fayad, A De Milito, MH Olofsson, ... Nature communications 5 (1), 3295, 2014 | 255 | 2014 |
Screening of natural products for therapeutic activity against solid tumors BS El-Menshawi, W Fayad, K Mahmoud, SM El-Hallouty, M El-Manawaty CSIR, 2010 | 148 | 2010 |
Screening for compounds that induce apoptosis of cancer cells grown as multicellular spheroids R Herrmann, W Fayad, S Schwarz, M Berndtsson, S Linder Journal of biomolecular screening 13 (1), 1-8, 2008 | 115 | 2008 |
Apoptosis inducing activity of steroidal constituents from Solanum xanthocarpum and Asparagus racemosus KK Bhutani, AT Paul, W Fayad, S Linder Phytomedicine 17 (10), 789-793, 2010 | 107 | 2010 |
Large-scale in Vitro. Screening of Egyptian Native and Cultivated Plants for Schistosomicidal Activity F Yousif, MS Hifnawy, G Soliman, L Boulos, T Labib, S Mahmoud, ... Pharmaceutical biology 45 (6), 501-510, 2007 | 93 | 2007 |
Novel hydrazide-hydrazone and amide substituted coumarin derivatives: Synthesis, cytotoxicity screening, microarray, radiolabeling and in vivo pharmacokinetic studies T Nasr, S Bondock, HM Rashed, W Fayad, M Youns, TM Sakr European journal of medicinal chemistry 151, 723-739, 2018 | 91 | 2018 |
Nonclassical antifolates, part 4. 5-(2-Aminothiazol-4-yl)-4-phenyl-4H-1, 2, 4-triazole-3-thiols as a new class of DHFR inhibitors: Synthesis, biological evaluation and … GS Hassan, SM El-Messery, FAM Al-Omary, ST Al-Rashood, ... European journal of medicinal chemistry 66, 135-145, 2013 | 80 | 2013 |
Novel activity of acriflavine against colorectal cancer tumor cells S Hassan, D Laryea, H Mahteme, J Felth, M Fryknäs, W Fayad, S Linder, ... Cancer science 102 (12), 2206-2213, 2011 | 74 | 2011 |
Ethosomes and lipid-coated chitosan nanocarriers for skin delivery of a chlorophyll derivative: a potential treatment of squamous cell carcinoma by photodynamic therapy S Nasr, M Rady, I Gomaa, T Syrovets, T Simmet, W Fayad, M Abdel-Kader International Journal of Pharmaceutics 568, 118528, 2019 | 59 | 2019 |
Identification of a novel topoisomerase inhibitor effective in cells overexpressing drug efflux transporters W Fayad, M Fryknäs, S Brnjic, MH Olofsson, R Larsson, S Linder PLoS One 4 (10), e7238, 2009 | 59 | 2009 |
Identification of agents that induce apoptosis of multicellular tumour spheroids: enrichment for mitotic inhibitors with hydrophobic properties W Fayad, L Rickardson, C Haglund, MH Olofsson, P D’Arcy, R Larsson, ... Chemical biology & drug design 78 (4), 547-557, 2011 | 57 | 2011 |
Biomaterials based on essential fatty acids and carbohydrates for chronic wounds AA Nada, AG Hassabo, W Fayad, HM Awad, AA Sleem, NM Shaffie, ... Journal of Applied Pharmaceutical Science 5 (3), 013-021, 2015 | 51 | 2015 |
Restriction of cisplatin induction of acute apoptosis to a subpopulation of cells in a three‐dimensional carcinoma culture model W Fayad, S Brnjic, D Berglind, S Blixt, MC Shoshan, M Berndtsson, ... International journal of cancer 125 (10), 2450-2455, 2009 | 51 | 2009 |
Therapeutic potentials of n-hexane extracts of the three medicinal mushrooms regarding their anti-colon cancer, antioxidant, and hypocholesterolemic capabilities W Elkhateeb, AN ELDien, E Fadl, A Elhagrasi, W Fayad, TC Wen Biodiversitas Journal of Biological Diversity 21 (6), 2020 | 46 | 2020 |
Contribution to in vitro screening of Egyptian plants for schistosomicidal activity F Yousif, G Wassel, L Boulos, T Labib, K Mahmoud, S El-Hallouty, ... Pharmaceutical biology 50 (6), 732-739, 2012 | 44 | 2012 |
TPGS surface modified bilosomes as boosting cytotoxic oral delivery systems of curcumin against doxorubicin resistant MCF-7 breast cancer cells H Hegazy, MM Amin, W Fayad, MY Zakaria International Journal of Pharmaceutics 619, 121717, 2022 | 41 | 2022 |
Caspicaosides E–K, triterpenoid saponins and cytotoxic acylated saponins from fruits of Gleditsia caspica Desf. FR Melek, IAA Kassem, T Miyase, W Fayad Phytochemistry 100, 110-119, 2014 | 41 | 2014 |
Biological capacity and chemical composition of secondary metabolites from representatives Japanese lichens EF Ahmed, WA Elkhateeb, HAA Taie, ME Rateb, W Fayad Journal of Applied Pharmaceutical Science 7 (1), 098-103, 2017 | 40 | 2017 |
3-Alkenyl-2-oxindoles: Synthesis, antiproliferative and antiviral properties against SARS-CoV-2 AS Girgis, SS Panda, AM Srour, A Abdelnaser, S Nasr, Y Moatasim, ... Bioorganic chemistry 114, 105131, 2021 | 36 | 2021 |
Insights into the in-vitro hypocholesterolemic, antioxidant, antirotavirus, and anticolon cancer activities of the methanolic extracts of a Japanese lichen, and a Japanese mushroom WA Elkhateeb, GM Daba, AN El-Dein, DH Sheir, W Fayad, MN Shaheen, ... Egyptian Pharmaceutical Journal 19 (1), 67-73, 2020 | 35 | 2020 |