Application of the threshold of toxicological concern (TTC) to the safety evaluation of cosmetic ingredients R Kroes, AG Renwick, V Feron, CL Galli, M Gibney, H Greim, RH Guy, ... Food and Chemical Toxicology 45 (12), 2533-2562, 2007 | 1387 | 2007 |
Current status of methods for defining the applicability domain of (quantitative) structure-activity relationships: The report and recommendations of ecvam workshop 52 TI Netzeva, AP Worth, T Aldenberg, R Benigni, MTD Cronin, P Gramatica, ... Alternatives to Laboratory Animals 33 (2), 155-173, 2005 | 932 | 2005 |
In vitro predictions of skin absorption of caffeine, testosterone, and benzoic acid: a multi-centre comparison study JJM Van de Sandt, JA Van Burgsteden, S Cage, PL Carmichael, I Dick, ... Regulatory Toxicology and Pharmacology 39 (3), 271-281, 2004 | 283 | 2004 |
A prevalidation study on in vitro tests for acute skin irritation: results and evaluation by the Management Team JH Fentem, D Briggs, C Chesné, GR Elliott, JW Harbell, JR Heylings, ... Toxicology in vitro 15 (1), 57-93, 2001 | 176 | 2001 |
Interactions of skin thickness and physicochemical properties of test compounds in percutaneous penetration studies SC Wilkinson, WJM Maas, JB Nielsen, LC Greaves, JJM van de Sandt, ... International archives of occupational and environmental health 79, 405-413, 2006 | 134 | 2006 |
The Use of In Vitro Toxicity Data and Physiologically Based Kinetic Modeling to Predict Dose-Response Curves for In Vivo Developmental Toxicity of Glycol Ethers … J Louisse, E de Jong, JJM van de Sandt, BJ Blaauboer, RA Woutersen, ... Toxicological Sciences 118 (2), 470-484, 2010 | 131 | 2010 |
The application of in vitro data in the derivation of the acceptable daily intake of food additives K Walton, R Walker, JJM Van De Sandt, JV Castell, A Knapp, ... Food and Chemical Toxicology 37 (12), 1175-1197, 1999 | 127 | 1999 |
Alternative methods for skin irritation testing: the current status: ECVAM skin irritation task force report 1 PA Botham, LK Earl, JH Fentem, R Roguet, JJM Van De Sandt Alternatives to Laboratory Animals 26 (2), 195-211, 1998 | 116 | 1998 |
REACH, non-testing approaches and the urgent need for a change in mind set G Schaafsma, ED Kroese, E Tielemans, JJM Van de Sandt, ... Regulatory Toxicology and Pharmacology 53 (1), 70-80, 2009 | 111 | 2009 |
Prediction of in vivo embryotoxic effect levels with a combination of in vitro studies and PBPK modelling M Verwei, JA van Burgsteden, CAM Krul, JJM van de Sandt, AP Freidig Toxicology Letters 165 (1), 79-87, 2006 | 104 | 2006 |
The Use of Human Keratinocytes and Human Skin Models for Predicting Skin Irritation: The Report and Recommendations of ECVAM Workshop 38, J van de Sandt, R Roguet, C Cohen, D Esdaile, M Ponec, E Corsini, ... Alternatives to Laboratory Animals 27 (5), 723-743, 1999 | 97 | 1999 |
Percutaneous penetration studies for risk assessment P Sartorelli, HR Andersen, J Angerer, J Corish, H Drexler, T Göen, ... Environmental Toxicology and Pharmacology 8 (2), 133-152, 2000 | 95 | 2000 |
Skin sensitisation and epidermal disposition: the relevance of epidermal disposition for sensitisation hazard identification and risk assessment: the report and recommendations … D Basketter, C Pease, G Kasting, I Kimber, S Casati, M Cronin, ... Alternatives to Laboratory Animals 35 (1), 137-154, 2007 | 91 | 2007 |
Comparative in Vitro–in Vivo Percutaneous Absorption of the Pesticide Propoxur JJM Van De Sandt, WJA Meuling, GR Elliott, NHP Cnubben, BC Hakkert Toxicological sciences 58 (1), 15-22, 2000 | 91 | 2000 |
Comparative in vitro–in vivo percutaneous penetration of the fungicide ortho-phenylphenol NHP Cnubben, GR Elliott, BC Hakkert, WJA Meuling, JJM van de Sandt Regulatory toxicology and pharmacology 35 (2), 198-208, 2002 | 79 | 2002 |
Relative Developmental Toxicity of Glycol Ether Alkoxy Acid Metabolites in the Embryonic Stem Cell Test as compared with the In Vivo Potency of their Parent … E de Jong, J Louisse, M Verwei, BJ Blaauboer, JJM van de Sandt, ... Toxicological sciences 110 (1), 117-124, 2009 | 77 | 2009 |
Xenobiotic metabolism in human skin and 3D human skin reconstructs: a review S Gibbs, JJM van de Sandt, HF Merk, DJ Lockley, RU Pendlington, ... Current Drug Metabolism 8 (8), 758-772, 2007 | 71 | 2007 |
Follow-up to the ECVAM Prevalidation Study on In Vitro Tests for Acute Skin Irritation: ECVAM Skin Irritation Task Force Report 2 V Zuang, M Balls, PA Botham, A Coquette, E Corsini, RD Curren, ... Alternatives to Laboratory Animals 30 (1), 109-129, 2002 | 58 | 2002 |
Evaluation of research activities and research needs to increase the impact and applicability of alternative testing strategies in risk assessment practice A Punt, MJWA Schiffelers, GJ Horbach, JJM van de Sandt, ... Regulatory Toxicology and Pharmacology 61 (1), 105-114, 2011 | 56 | 2011 |
New in vitro dermal absorption database and the prediction of dermal absorption under finite conditions for risk assessment purposes HE Buist, JA van Burgsteden, AP Freidig, WJM Maas, JJM van de Sandt Regulatory toxicology and pharmacology 57 (2-3), 200-209, 2010 | 49 | 2010 |