| Guidelines for the use and interpretation of assays for monitoring autophagy 1 DJ Klionsky, AK Abdel-Aziz, S Abdelfatah, M Abdellatif, A Abdoli, S Abel, ... autophagy 17 (1), 1, 2021 | 2520 | 2021 |
| Pharmacologic ascorbic acid concentrations selectively kill cancer cells: action as a pro-drug to deliver hydrogen peroxide to tissues Q Chen, MG Espey, MC Krishna, JB Mitchell, CP Corpe, GR Buettner, ... Proceedings of the National Academy of Sciences 102 (38), 13604-13609, 2005 | 1344 | 2005 |
| Pharmacologic doses of ascorbate act as a prooxidant and decrease growth of aggressive tumor xenografts in mice Q Chen, MG Espey, AY Sun, C Pooput, KL Kirk, MC Krishna, DB Khosh, ... Proceedings of the National Academy of Sciences 105 (32), 11105-11109, 2008 | 1095 | 2008 |
| Ascorbate in pharmacologic concentrations selectively generates ascorbate radical and hydrogen peroxide in extracellular fluid in vivo Q Chen, MG Espey, AY Sun, JH Lee, MC Krishna, E Shacter, PL Choyke, ... Proceedings of the National Academy of Sciences 104 (21), 8749-8754, 2007 | 857 | 2007 |
| High-dose parenteral ascorbate enhanced chemosensitivity of ovarian cancer and reduced toxicity of chemotherapy Y Ma, J Chapman, M Levine, K Polireddy, J Drisko, Q Chen Science translational medicine 6 (222), 222ra18-222ra18, 2014 | 591 | 2014 |
| Vitamin C: intravenous use by complementary and alternative medicine practitioners and adverse effects SJ Padayatty, AY Sun, Q Chen, MG Espey, J Drisko, M Levine PloS one 5 (7), e11414, 2010 | 429 | 2010 |
| Pharmacologic ascorbate synergizes with gemcitabine in preclinical models of pancreatic cancer MG Espey, P Chen, B Chalmers, J Drisko, AY Sun, M Levine, Q Chen Free Radical Biology and Medicine 50 (11), 1610-1619, 2011 | 224 | 2011 |
| Synthesis, acute toxicities, and antitumor effects of novel 9-substituted β-carboline derivatives R Cao, Q Chen, X Hou, H Chen, H Guan, Y Ma, W Peng, A Xu Bioorganic & medicinal chemistry 12 (17), 4613-4623, 2004 | 224 | 2004 |
| Antitumor and neurotoxic effects of novel harmine derivatives and structure‐activity relationship analysis Q Chen, R Chao, H Chen, X Hou, H Yan, S Zhou, W Peng, A Xu International Journal of Cancer 114 (5), 675-682, 2005 | 217 | 2005 |
| High dose parenteral ascorbate inhibited pancreatic cancer growth and metastasis: mechanisms and a phase I/IIa study K Polireddy, R Dong, G Reed, J Yu, P Chen, S Williamson, PC Violet, ... Scientific reports 7 (1), 17188, 2017 | 167 | 2017 |
| Pharmacological ascorbate induces cytotoxicity in prostate cancer cells through ATP depletion and induction of autophagy P Chen, J Yu, B Chalmers, J Drisko, J Yang, B Li, Q Chen Anti-Cancer Drugs 23 (4), 437-444, 2012 | 122 | 2012 |
| Cancer of the pancreas: molecular pathways and current advancement in treatment K Polireddy, Q Chen Journal of Cancer 7 (11), 1497, 2016 | 120 | 2016 |
| Antitumor activities of Rauwolfia vomitoria extract and potentiation of carboplatin effects against ovarian cancer J Yu, Y Ma, J Drisko, Q Chen Current Therapeutic Research 75, 8-14, 2013 | 108 | 2013 |
| GSK‐3β controls autophagy by modulating LKB1‐AMPK pathway in prostate cancer cells A Sun, C Li, R Chen, Y Huang, Q Chen, X Cui, H Liu, JB Thrasher, B Li The Prostate 76 (2), 172-183, 2016 | 103 | 2016 |
| Synthesis and in vitro cytotoxic evaluation of 1, 3-bisubstituted and 1, 3, 9-trisubstituted β-carboline derivatives R Cao, W Peng, H Chen, X Hou, H Guan, Q Chen, Y Ma, A Xu European journal of medicinal chemistry 40 (3), 249-257, 2005 | 96 | 2005 |
| Losing and finding a way at C: new promise for pharmacologic ascorbate in cancer treatment M Levine, MG Espey, Q Chen Free radical biology & medicine 47 (1), 27, 2009 | 86 | 2009 |
| Anti-cancer effect of pharmacologic ascorbate and its interaction with supplementary parenteral glutathione in preclinical cancer models P Chen, J Stone, G Sullivan, JA Drisko, Q Chen Free Radical Biology and Medicine 51 (3), 681-687, 2011 | 81 | 2011 |
| Pharmacologic ascorbate induces neuroblastoma cell death by hydrogen peroxide mediated DNA damage and reduction in cancer cell glycolysis E Ma, P Chen, HM Wilkins, T Wang, RH Swerdlow, Q Chen Free Radical Biology and Medicine 113, 36-47, 2017 | 80 | 2017 |
| Identification of recurrent fusion genes across multiple cancer types YP Yu, P Liu, J Nelson, RL Hamilton, R Bhargava, G Michalopoulos, ... Scientific reports 9 (1), 1074, 2019 | 65 | 2019 |
| Apoptosis of a human non-small cell lung cancer (NSCLC) cell line, PLA-801, induced by acutiaporberine, a novel bisalkaloid derived from Thalictrum acutifolium (Hand.-Mazz.) Boivin Q Chen, W Peng, A Xu Biochemical Pharmacology 63 (8), 1389-1396, 2002 | 56 | 2002 |
Michael Graham Espey, PhD MTDeputy Associate Director, Division of Cancer Diagnosis & Treatment, National Cancer Institute確認したメール アドレス: nih.gov