Pan-cancer analysis of whole genomes Nature 578 (7793), 82-93, 2020 | 2546* | 2020 |
Why weight? Modelling sample and observational level variability improves power in RNA-seq analyses R Liu, AZ Holik, S Su, N Jansz, K Chen, HS Leong, ME Blewitt, ... Nucleic acids research 43 (15), e97-e97, 2015 | 532 | 2015 |
A global metagenomic map of urban microbiomes and antimicrobial resistance D Danko, D Bezdan, EE Afshin, S Ahsanuddin, C Bhattacharya, DJ Butler, ... Cell 184 (13), 3376-3393. e17, 2021 | 280 | 2021 |
Dual inhibition of BCL-XL and MCL-1 is required to induce tumour regression in lung squamous cell carcinomas sensitive to FGFR inhibition CE Weeden, C Ah-Cann, AZ Holik, J Pasquet, JM Garnier, D Merino, ... Oncogene 37 (32), 4475-4488, 2018 | 97 | 2018 |
Setdb1-mediated H3K9 methylation is enriched on the inactive X and plays a role in its epigenetic silencing A Keniry, LJ Gearing, N Jansz, J Liu, AZ Holik, PF Hickey, SA Kinkel, ... Epigenetics & chromatin 9, 1-20, 2016 | 74 | 2016 |
Repression of Igf1 expression by Ezh2 prevents basal cell differentiation in the developing lung LA Galvis, AZ Holik, KM Short, J Pasquet, ATL Lun, ME Blewitt, IM Smyth, ... Development 142 (8), 1458-1469, 2015 | 65 | 2015 |
Brg1 loss attenuates aberrant wnt-signalling and prevents wnt-dependent tumourigenesis in the murine small intestine AZ Holik, M Young, J Krzystyniak, GT Williams, D Metzger, BY Shorning, ... PLoS genetics 10 (7), e1004453, 2014 | 54 | 2014 |
Retrospective evaluation of whole exome and genome mutation calls in 746 cancer samples WU Meyerson, LJ Dursi, LB Wang, G Dong, WW Liang, A Weerasinghe, ... Nature Publishing Group UK, 2020 | 45* | 2020 |
Brg1 is required for stem cell maintenance in the murine intestinal epithelium in a tissue‐specific manner AZ Holik, J Krzystyniak, M Young, K Richardson, T Jardé, P Chambon, ... Stem Cells 31 (11), 2457-2466, 2013 | 42 | 2013 |
Covering all your bases: incorporating intron signal from RNA-seq data S Lee, AY Zhang, S Su, AP Ng, AZ Holik, ML Asselin-Labat, ME Ritchie, ... NAR Genomics and Bioinformatics 2 (3), lqaa073, 2020 | 40 | 2020 |
RNA-seq mixology: designing realistic control experiments to compare protocols and analysis methods AZ Holik, CW Law, R Liu, Z Wang, W Wang, J Ahn, ML Asselin-Labat, ... Nucleic acids research 45 (5), e30-e30, 2017 | 36 | 2017 |
Germline determinants of the somatic mutation landscape in 2,642 cancer genomes SM Waszak, G Tiao, B Zhu, T Rausch, F Muyas, B Rodriguez-Martin, ... BioRxiv, 208330, 2017 | 35 | 2017 |
Cisplatin increases sensitivity to FGFR inhibition in patient-derived xenograft models of lung squamous cell carcinoma CE Weeden, AZ Holik, RJ Young, SB Ma, JM Garnier, SB Fox, P Antippa, ... Molecular cancer therapeutics 16 (8), 1610-1622, 2017 | 28 | 2017 |
Environmental enrichment induces epigenomic and genome organization changes relevant for cognition S Espeso-Gil, AZ Holik, S Bonnin, S Jhanwar, S Chandrasekaran, ... Frontiers in Molecular Neuroscience 14, 664912, 2021 | 27 | 2021 |
Environmental enrichment induces epigenomic and genome organization changes relevant for cognition S Espeso-Gil, AZ Holik, S Bonnin, S Jhanwar, S Chandrasekaran, ... Frontiers in Molecular Neuroscience 14, 664912, 2021 | 27 | 2021 |
Pan-cancer analysis of whole genomes G Demidov, O Drechsel, S Ossowski, X Estivill, G Escaramís, M Bosio, ... Nature. 2020 Feb; 578 (7793): 82-93, 2020 | 12* | 2020 |
Quantitative proteomic analysis of EZH2 inhibition in acute myeloid leukemia reveals the targets and pathways that precede the induction of cell death JJ Sandow, G Infusini, AZ Holik, G Brumatti, TV Averink, PG Ekert, ... PROTEOMICS–Clinical Applications 11 (9-10), 1700013, 2017 | 7 | 2017 |
The LIM-domain only protein 4 contributes to lung epithelial cell proliferation but is not essential for tumor progression. AZ Holik, CE Filby, J Pasquet, K Viitaniemi, J Ciciulla, KD Sutherland, ... Respiratory research 16 (1), 67, 2015 | 7 | 2015 |
A data-driven approach to characterizing intron signal in RNA-seq data AY Zhang, S Su, AP Ng, AZ Holik, ML Asselin-Labat, ME Ritchie, CW Law bioRxiv, 352823, 2018 | 5 | 2018 |
Why weight? Combining voom with estimates of sample quality improves power in RNA-seq analyses R Liu, AZ Holik, S Su, N Jansz, K Chen, HS Leong, ME Blewitt, ... Nucleic Acids Research 43 (15), e97, 2015 | 5 | 2015 |