フォロー
Sanchari Bhattacharyya
Sanchari Bhattacharyya
Senior Scientist II, Novartis Institutes of Biomedical Research
確認したメール アドレス: novartis.com
タイトル
引用先
引用先
Protein homeostasis imposes a barrier on functional integration of horizontally transferred genes in bacteria
S Bershtein, AWR Serohijos, S Bhattacharyya, M Manhart, JM Choi, W Mu, ...
PLoS genetics 11 (10), e1005612, 2015
842015
Accessibility of the Shine-Dalgarno sequence dictates N-terminal codon bias in E. coli
S Bhattacharyya, WM Jacobs, BV Adkar, J Yan, W Zhang, EI Shakhnovich
Molecular cell 70 (5), 894-905. e5, 2018
702018
Transient protein-protein interactions perturb E. coli metabolome and cause gene dosage toxicity
S Bhattacharyya, S Bershtein, J Yan, T Argun, AI Gilson, SA Trauger, ...
elife 5, e20309, 2016
672016
Optimization of lag phase shapes the evolution of a bacterial enzyme
BV Adkar, M Manhart, S Bhattacharyya, J Tian, M Musharbash, ...
Nature ecology & evolution 1 (6), 0149, 2017
522017
Packing in molten globules and native states
S Bhattacharyya, R Varadarajan
Current Opinion in Structural Biology 23 (1), 11-21, 2013
482013
Systems-level response to point mutations in a core metabolic enzyme modulates genotype-phenotype relationship
S Bershtein, JM Choi, S Bhattacharyya, B Budnik, E Shakhnovich
Cell reports 11 (4), 645-656, 2015
392015
Design of a non-glycosylated outer domain-derived HIV-1 gp120 immunogen that binds to CD4 and induces neutralizing antibodies
S Bhattacharyya, RE Rajan, Y Swarupa, U Rathore, A Verma, ...
Journal of Biological Chemistry 285 (35), 27100-27110, 2010
382010
Refolding and simultaneous purification by three‐phase partitioning of recombinant proteins from inclusion bodies
S Raghava, B Barua, PK Singh, M Das, L Madan, S Bhattacharyya, ...
Protein Science 17 (11), 1987-1997, 2008
362008
Design of an Escherichia coli expressed HIV-1 gp120 fragment immunogen that binds to b12 and induces broad and potent neutralizing antibodies
S Bhattacharyya, P Singh, U Rathore, M Purwar, D Wagner, H Arendt, ...
Journal of Biological Chemistry 288 (14), 9815-9825, 2013
302013
Designed cyclic permutants of HIV-1 gp120: implications for envelope trimer structure and immunogen design
P Saha, S Bhattacharyya, S Kesavardhana, ER Miranda, PSS Ali, ...
Biochemistry 51 (9), 1836-1847, 2012
252012
Substrate inhibition imposes fitness penalty at high protein stability
BV Adkar, S Bhattacharyya, AI Gilson, W Zhang, EI Shakhnovich
Proceedings of the National Academy of Sciences 116 (23), 11265-11274, 2019
212019
Design and characterization of stabilized derivatives of human CD4D12 and CD4D1
P Saha, B Barua, S Bhattacharyya, MM Balamurali, WR Schief, D Baker, ...
Biochemistry 50 (37), 7891-7900, 2011
162011
Strategy for purifying maltose binding protein fusion proteins by affinity precipitation
S Raghava, S Aquil, S Bhattacharyya, R Varadarajan, MN Gupta
Journal of Chromatography A 1194 (1), 90-95, 2008
162008
Bacterially expressed HIV-1 gp120 outer-domain fragment immunogens with improved stability and affinity for CD4-binding site neutralizing antibodies
U Rathore, M Purwar, VS Vignesh, R Das, AA Kumar, S Bhattacharyya, ...
Journal of Biological Chemistry 293 (39), 15002-15020, 2018
152018
Allosteric communication between ligand binding domains modulates substrate inhibition in adenylate kinase
D Scheerera, BV Adkar, S Bhattacharyya, D Levya, M Iljinaa, I Rivena, ...
Proceedings of the National Academy of Sciences 120 (18), e2219855120, 2023
122023
Design, display and immunogenicity of HIV1 gp120 fragment immunogens on virus-like particles
M Purwar, JK Pokorski, P Singh, S Bhattacharyya, H Arendt, J DeStefano, ...
Vaccine 36 (42), 6345-6353, 2018
122018
Metabolic response to point mutations reveals principles of modulation of in vivo enzyme activity and phenotype
S Bhattacharyya, S Bershtein, BV Adkar, J Woodard, EI Shakhnovich
Molecular Systems Biology 17 (6), e10200, 2021
102021
Gene dosage experiments in enterobacteriaceae using Arabinose-regulated promoters
S Bhattacharyya, S Bershtein, EI Shakhnovich
Bio-protocol 7 (14), 2017
42017
HIV-1 Envelope Based Fragments
SK Phogat, R Varadarajan, S Bhattacharyya
US Patent App. 13/038,828, 2011
42011
Targeting The CD4 Biniding Site In HIV-1 Immunogen Design
S Bhattacharyya
2016
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論文 1–20