Negative regulation of PKB/Akt-dependent cell survival by the tumor suppressor PTEN V Stambolic, A Suzuki, JL De La Pompa, GM Brothers, C Mirtsos, T Sasaki, ... Cell 95 (1), 29-39, 1998 | 3318 | 1998 |
Long noncoding RNA HOTAIR regulates polycomb-dependent chromatin modification and is associated with poor prognosis in colorectal cancers R Kogo, T Shimamura, K Mimori, K Kawahara, S Imoto, T Sudo, F Tanaka, ... Cancer research 71 (20), 6320-6326, 2011 | 1513 | 2011 |
Function of PI3Kγ in thymocyte development, T cell activation, and neutrophil migration T Sasaki, J Irie-Sasaki, RG Jones, AJ Oliveira-dos-Santos, WL Stanford, ... Science 287 (5455), 1040-1046, 2000 | 1338 | 2000 |
Electrical signals control wound healing through phosphatidylinositol-3-OH kinase-γ and PTEN M Zhao, B Song, J Pu, T Wada, B Reid, G Tai, F Wang, A Guo, ... Nature 442 (7101), 457-460, 2006 | 1238 | 2006 |
High cancer susceptibility and embryonic lethality associated with mutation of the PTEN tumor suppressor gene in mice A Suzuki, JL De La Pompa, V Stambolic, AJ Elia, T Sasaki, ... Current biology 8 (21), 1169-1178, 1998 | 1020 | 1998 |
Method of using a guide wire, therapeutic instrument and endoscope T Ootawara, A Suzuki, H Kubokawa, H Kimura, O Tamada, M Nakada, ... US Patent 7,341,555, 2008 | 936 | 2008 |
Hepatocyte-specific Pten deficiency results in steatohepatitis and hepatocellular carcinomas Y Horie, A Suzuki, E Kataoka, T Sasaki, K Hamada, J Sasaki, K Mizuno, ... The Journal of clinical investigation 113 (12), 1774-1783, 2004 | 829 | 2004 |
Regulation of myocardial contractility and cell size by distinct PI3K-PTEN signaling pathways MA Crackower, GY Oudit, I Kozieradzki, R Sarao, H Sun, T Sasaki, ... Cell 110 (6), 737-749, 2002 | 800 | 2002 |
T cell-specific loss of Pten leads to defects in central and peripheral tolerance A Suzuki, MT Yamaguchi, T Ohteki, T Sasaki, T Kaisho, Y Kimura, ... Immunity 14 (5), 523-534, 2001 | 718 | 2001 |
Musashi1: an evolutionally conserved marker for CNS progenitor cells including neural stem cells Y Kaneko, S Sakakibara, T Imai, A Suzuki, Y Nakamura, K Sawamoto, ... Developmental neuroscience 22 (1-2), 139-153, 2000 | 668 | 2000 |
Deletion of Pten in mouse brain causes seizures, ataxia and defects in soma size resembling Lhermitte-Duclos disease SA Backman, V Stambolic, A Suzuki, J Haight, A Elia, J Pretorius, ... Nature genetics 29 (4), 396-403, 2001 | 610 | 2001 |
Notch–RBP-J signaling is involved in cell fate determination of marginal zone B cells K Tanigaki, H Han, N Yamamoto, K Tashiro, M Ikegawa, K Kuroda, ... Nature immunology 3 (5), 443-450, 2002 | 585 | 2002 |
High incidence of breast and endometrial neoplasia resembling human Cowden syndrome in pten+/− mice V Stambolic, MS Tsao, D Macpherson, A Suzuki, WB Chapman, TW Mak Cancer research 60 (13), 3605-3611, 2000 | 489 | 2000 |
Prediction of human hepatic clearance from in vivo animal experiments and in vitro metabolic studies with liver microsomes from animals and humans Y Naritomi, S Terashita, S Kimura, A Suzuki, A Kagayama, Y Sugiyama Drug Metabolism and Disposition 29 (10), 1316-1324, 2001 | 405 | 2001 |
The PTEN/PI3K pathway governs normal vascular development and tumor angiogenesis K Hamada, T Sasaki, PA Koni, M Natsui, H Kishimoto, J Sasaki, N Yajima, ... Genes & development 19 (17), 2054-2065, 2005 | 403 | 2005 |
Enhanced PIP3 signaling in POMC neurons causes KATP channel activation and leads to diet-sensitive obesity L Plum, X Ma, B Hampel, N Balthasar, R Coppari, H Münzberg, ... The Journal of clinical investigation 116 (7), 1886-1901, 2006 | 366 | 2006 |
Control of cell polarity and motility by the PtdIns(3,4,5)P3 phosphatase SHIP1 M Nishio, K Watanabe, J Sasaki, C Taya, S Takasuga, R Iizuka, T Balla, ... Nature cell biology 9 (1), 36-44, 2007 | 340 | 2007 |
Brca2 is required for embryonic cellular proliferation in the mouse. A Suzuki, JL de la Pompa, R Hakem, A Elia, R Yoshida, R Mo, H Nishina, ... Genes & development 11 (10), 1242-1252, 1997 | 338 | 1997 |
Synthesis of sterically hindered biaryls via the palladium-catalyzed cross-coupling reaction of arylboronic acids or their esters with haloarenes T Watanabe, N Miyaura, A Suzuki Synlett 1992 (03), 207-210, 1992 | 336 | 1992 |
Mammalian phosphoinositide kinases and phosphatases T Sasaki, S Takasuga, J Sasaki, S Kofuji, S Eguchi, M Yamazaki, A Suzuki Progress in lipid research 48 (6), 307-343, 2009 | 322 | 2009 |