Mutations associated with failure of raltegravir treatment affect integrase sensitivity to the inhibitor in vitro I Malet, O Delelis, MA Valantin, B Montes, C Soulie, M Wirden, ... Antimicrobial agents and chemotherapy 52 (4), 1351-1358, 2008 | 346 | 2008 |
Integrase and integration: biochemical activities of HIV-1 integrase O Delelis, K Carayon, A Saïb, E Deprez, JF Mouscadet Retrovirology 5, 1-13, 2008 | 334 | 2008 |
Extracellular ATP acts on P2Y2 purinergic receptors to facilitate HIV-1 infection C Séror, MT Melki, F Subra, SQ Raza, M Bras, H Saïdi, R Nardacci, ... Journal of Experimental Medicine 208 (9), 1823-1834, 2011 | 210 | 2011 |
Relationship between the oligomeric status of HIV-1 integrase on DNA and enzymatic activity E Guiot, K Carayon, O Delelis, F Simon, P Tauc, E Zubin, M Gottikh, ... Journal of Biological Chemistry 281 (32), 22707-22719, 2006 | 192 | 2006 |
The G140S mutation in HIV integrases from raltegravir-resistant patients rescues catalytic defect due to the resistance Q148H mutation O Delelis, I Malet, L Na, L Tchertanov, V Calvez, AG Marcelin, F Subra, ... Nucleic Acids Research 37 (4), 1193-1201, 2009 | 166 | 2009 |
Dual inhibition of HIV-1 replication by integrase-LEDGF allosteric inhibitors is predominant at the post-integration stage E Le Rouzic, D Bonnard, S Chasset, JM Bruneau, F Chevreuil, F Le Strat, ... Retrovirology 10, 1-21, 2013 | 146 | 2013 |
Resistance to HIV-1 integrase inhibitors: a structural perspective JF Mouscadet, O Delelis, AG Marcelin, L Tchertanov Drug Resistance Updates 13 (4-5), 139-150, 2010 | 101 | 2010 |
Quasispecies variant dynamics during emergence of resistance to raltegravir in HIV-1-infected patients I Malet, O Delelis, C Soulie, M Wirden, L Tchertanov, P Mottaz, G Peytavin, ... Journal of antimicrobial chemotherapy 63 (4), 795-804, 2009 | 101 | 2009 |
Impact of Y143 HIV-1 Integrase Mutations on Resistance to Raltegravir In Vitro and In Vivo O Delelis, S Thierry, F Subra, F Simon, I Malet, C Alloui, S Sayon, ... Antimicrobial agents and chemotherapy 54 (1), 491-501, 2010 | 100 | 2010 |
Foamy viruses—a world apart O Delelis, J Lehmann-Che, A Saïb Current opinion in microbiology 7 (4), 400-406, 2004 | 99 | 2004 |
Quantitative analysis of the time-course of viral DNA forms during the HIV-1 life cycle S Munir, S Thierry, F Subra, E Deprez, O Delelis Retrovirology 10, 1-18, 2013 | 93 | 2013 |
Chromatin tethering of incoming foamy virus by the structural Gag protein J Tobaly‐Tapiero, P Bittoun, J Lehmann‐Che, O Delelis, ML Giron, ... Traffic 9 (10), 1717-1727, 2008 | 93 | 2008 |
Mutations located outside the integrase gene can confer resistance to HIV-1 integrase strand transfer inhibitors I Malet, F Subra, C Charpentier, G Collin, D Descamps, V Calvez, ... MBio 8 (5), 10.1128/mbio. 00922-17, 2017 | 89 | 2017 |
Alu-LTR Real-Time Nested PCR Assay for Quantifying Integrated HIV-1 DNA A Brussel, O Delelis, P Sonigo Human Retrovirus Protocols: Virology and Molecular Biology, 139-154, 2005 | 89 | 2005 |
New raltegravir resistance pathways induce broad cross-resistance to all currently used integrase inhibitors I Malet, L Gimferrer Arriaga, A Artese, G Costa, L Parrotta, S Alcaro, ... Journal of Antimicrobial Chemotherapy 69 (8), 2118-2122, 2014 | 85 | 2014 |
Identification of highly conserved residues involved in inhibition of HIV-1 RNase H function by diketo acid derivatives A Corona, FS Di Leva, S Thierry, L Pescatori, G Cuzzucoli Crucitti, ... Antimicrobial agents and chemotherapy 58 (10), 6101-6110, 2014 | 80 | 2014 |
Inhibition of early steps of HIV-1 replication by SNF5/Ini1 M Maroun, O Delelis, G Coadou, T Bader, E Ségéral, G Mbemba, C Petit, ... Journal of Biological Chemistry 281 (32), 22736-22743, 2006 | 77 | 2006 |
Biphasic DNA synthesis in spumaviruses O Delelis, A Saïb, P Sonigo Journal of virology 77 (14), 8141-8146, 2003 | 71 | 2003 |
Impairment of human immunodeficiency virus type-1 integrase SUMOylation correlates with an early replication defect A Zamborlini, A Coiffic, G Beauclair, O Delelis, J Paris, Y Koh, F Magne, ... Journal of Biological Chemistry 286 (23), 21013-21022, 2011 | 69 | 2011 |
Insight into the integrase-DNA recognition mechanism: A specific DNA-binding mode revealed by an enzymatically labeled integrase O Delelis, K Carayon, E Guiot, H Leh, P Tauc, JC Brochon, JF Mouscadet, ... Journal of Biological Chemistry 283 (41), 27838-27849, 2008 | 58 | 2008 |