An atlas of healthy and injured cell states and niches in the human kidney BB Lake, R Menon, S Winfree, Q Hu, R Melo Ferreira, K Kalhor, ... Nature 619 (7970), 585-594, 2023 | 302 | 2023 |
Higher prevalence of anemia with diabetes mellitus in moderate kidney insufficiency: The Kidney Early Evaluation Program TM El-Achkar, SE Ohmit, PA Mccullough, ED Crook, WW Brown, R Grimm, ... Kidney international 67 (4), 1483-1488, 2005 | 245 | 2005 |
Rate of kidney function decline associates with mortality Z Al-Aly, A Zeringue, J Fu, MI Rauchman, JR McDonald, TM El-Achkar, ... Journal of the American Society of Nephrology 21 (11), 1961-1969, 2010 | 217 | 2010 |
Tamm-Horsfall protein protects the kidney from ischemic injury by decreasing inflammation and altering TLR4 expression TM El-Achkar, XR Wu, M Rauchman, R McCracken, S Kiefer, PC Dagher American Journal of Physiology-Renal Physiology 295 (2), F534-F544, 2008 | 198 | 2008 |
Sepsis induces changes in the expression and distribution of Toll-like receptor 4 in the rat kidney TM El-Achkar, X Huang, Z Plotkin, RM Sandoval, GJ Rhodes, PC Dagher American Journal of Physiology-Renal Physiology 290 (5), F1034-F1043, 2006 | 189 | 2006 |
Endotoxin uptake by S1 proximal tubular segment causes oxidative stress in the downstream S2 segment R Kalakeche, T Hato, G Rhodes, KW Dunn, TM El-Achkar, Z Plotkin, ... Journal of the American Society of Nephrology 22 (8), 1505-1516, 2011 | 182 | 2011 |
Early nephrologist involvement in hospital-acquired acute kidney injury: a pilot study G Balasubramanian, Z Al-Aly, A Moiz, M Rauchman, Z Zhang, ... American journal of kidney diseases 57 (2), 228-234, 2011 | 173 | 2011 |
Uromodulin in kidney injury: an instigator, bystander, or protector? TM El-Achkar, XR Wu American journal of kidney diseases 59 (3), 452-461, 2012 | 150 | 2012 |
Tamm-Horsfall protein translocates to the basolateral domain of thick ascending limbs, interstitium, and circulation during recovery from acute kidney injury TM El-Achkar, R McCracken, Y Liu, MR Heitmeier, S Bourgeois, J Ryerse, ... American Journal of Physiology-Renal Physiology 304 (8), F1066-F1075, 2013 | 128 | 2013 |
Integration of spatial and single-cell transcriptomics localizes epithelial cell–immune cross-talk in kidney injury RM Ferreira, AR Sabo, S Winfree, KS Collins, D Janosevic, ... JCI insight 6 (12), 2021 | 122 | 2021 |
Rationale and design of the kidney precision medicine project IH de Boer, CE Alpers, EU Azeloglu, UGJ Balis, JM Barasch, L Barisoni, ... Kidney international 99 (3), 498-510, 2021 | 122 | 2021 |
The orchestrated cellular and molecular responses of the kidney to endotoxin define a precise sepsis timeline D Janosevic, J Myslinski, TW McCarthy, A Zollman, F Syed, X Xuei, H Gao, ... Elife 10, e62270, 2021 | 107 | 2021 |
Uromodulin (Tamm–Horsfall protein): Guardian of urinary and systemic homeostasis R Micanovic, K LaFavers, PS Garimella, XR Wu, TM El-Achkar Nephrology Dialysis Transplantation 35 (1), 33-43, 2020 | 99 | 2020 |
A reference tissue atlas for the human kidney J Hansen, R Sealfon, R Menon, MT Eadon, BB Lake, B Steck, K Anjani, ... Science advances 8 (23), eabn4965, 2022 | 97 | 2022 |
Tamm-Horsfall protein-deficient thick ascending limbs promote injury to neighboring S3 segments in an MIP-2-dependent mechanism TM El-Achkar, R McCracken, M Rauchman, MR Heitmeier, Z Al-Aly, ... American Journal of Physiology-Renal Physiology 300 (4), F999-F1007, 2011 | 89 | 2011 |
Tamm-Horsfall protein regulates mononuclear phagocytes in the kidney R Micanovic, S Khan, D Janosevic, ME Lee, T Hato, EF Srour, S Winfree, ... Journal of the American Society of Nephrology 29 (3), 841-856, 2018 | 85 | 2018 |
Renal Toll-like receptors: recent advances and implications for disease TM El-Achkar, PC Dagher Nature clinical practice Nephrology 2 (10), 568-581, 2006 | 80 | 2006 |
Tumor necrosis factor-α blockade, cardiovascular outcomes, and survival in rheumatoid arthritis Z Al-Aly, H Pan, A Zeringue, H Xian, JR McDonald, TM El-Achkar, S Eisen Translational Research 157 (1), 10-18, 2011 | 78 | 2011 |
Pathways of renal injury in systemic gram‐negative sepsis TM El‐Achkar, M Hosein, PC Dagher European journal of clinical investigation 38, 39-44, 2008 | 75 | 2008 |
Circulating uromodulin inhibits systemic oxidative stress by inactivating the TRPM2 channel KA LaFavers, E Macedo, PS Garimella, C Lima, S Khan, J Myslinski, ... Science translational medicine 11 (512), eaaw3639, 2019 | 70 | 2019 |