| QSP toolbox: computational implementation of integrated workflow components for deploying multi-scale mechanistic models Y Cheng, CJ Thalhauser, S Smithline, J Pagidala, M Miladinov, ... The AAPS journal 19, 1002-1016, 2017 | 52 | 2017 |
| Virtual populations for quantitative systems pharmacology models Y Cheng, R Straube, AE Alnaif, L Huang, TA Leil, BJ Schmidt Systems medicine, 129-179, 2022 | 36 | 2022 |
| Double reweighted sparse regression and graph regularization for hyperspectral unmixing S Wang, TZ Huang, XL Zhao, G Liu, Y Cheng Remote Sensing 10 (7), 1046, 2018 | 35 | 2018 |
| A Model for Direction Sensing in Dictyostelium discoideum: Ras Activity and Symmetry Breaking Driven by a Gβγ-Mediated, Gα2-Ric8 -- Dependent Signal … Y Cheng, H Othmer PLoS computational biology 12 (5), e1004900, 2016 | 30 | 2016 |
| A spatially distributed computational model of brain cellular metabolism D Calvetti, Y Cheng, E Somersalo Journal of theoretical biology 376, 48-65, 2015 | 30 | 2015 |
| The Metabolism of Neurons and Astrocytes Through Mathematical Models E Somersalo, Y Cheng, D Calvetti Annals of Biomedical Engineering, 1-17, 2012 | 28 | 2012 |
| The roles of signaling in cytoskeletal changes, random movement, direction-sensing and polarization of eukaryotic cells Y Cheng, B Felix, HG Othmer Cells 9 (6), 1437, 2020 | 23 | 2020 |
| Uncertainty quantification in flux balance analysis of spatially lumped and distributed models of neuron–astrocyte metabolism D Calvetti, Y Cheng, E Somersalo Journal of mathematical biology 73, 1823-1849, 2016 | 11 | 2016 |
| Antibodies to Modulate Surface Receptor Systems Are Often Bivalent and Must Compete in a Two‐Dimensional Cell Contact Region BJ Schmidt, C Bee, M Han, Y Jing, Y Cheng, DJ Tenney, TA Leil CPT: Pharmacometrics & Systems Pharmacology 8 (12), 873, 2019 | 5 | 2019 |
| Development of a Quantitative Systems Pharmacology (QSP) Toolbox and Virtual Population (VPop) for Affinity-Drug Conjugate (ADC) Research Y Cheng, HE Vezina, M Gupta, C Pan, TA Leil, BJ Schmidt J Pharmacokinet Pharmacodynam 43 (1), S47, 2016 | 2 | 2016 |
| Development of a quantitative systems pharmacology (QSP) model to support dose optimization of DS-1103a (anti SIRPa antibody) in combination with trastuzumab deruxtecan in … Y Cheng, P Vuppala, U Sarma, V Chelliah, P Graaf, T Karibe, S Hayashi, ... Journal of Clinical Oncology 41 (16_suppl), e14509-e14509, 2023 | 1 | 2023 |
| Computational models of brain energy metabolism at different scales Y Cheng Case Western Reserve University, 2014 | 1 | 2014 |
| Dosing and administration of non-fucosylated anti-ctla-4 antibody as monotherapy LP JAMES, Y CHENG, BJ Schmidt, JJ Engelhardt, L Li WO Patent WO2022098952A1, 2024 | | 2024 |
| 375TiP A phase I, 2-part, multicenter, first-in-human dose-escalation and dose-expansion study of DS-1103a with trastuzumab deruxtecan (T-DXd) in patients with advanced solid … L Cavalcante, LL Siu, J Toso, D Mires, R Shiga, J Maruca, G Ayele, ... Annals of Oncology 34, S333, 2023 | | 2023 |
| A virtual population (VPop) development workflow with improved efficiency and scale applied to immuno-oncology quantitative systems pharmacology models (I-O QSP platforms) Y Cheng, MD Shahinuzzaman, R Straube, A Alnaif, R Konduri, ... ACoP11 2 (ISSN:2688-3953), 2020 | | 2020 |
| An automated iterative virtual population development workflow for calibration of multi-therapy immunooncology quantitative systems pharmacology models (I-O QSP platforms) to … Y Cheng, BJ Schmidt ACoP10, 2019 | | 2019 |
| Energy Demand and Metabolite Partitioning in Spatially Lumped and Distributed Models of Neuron-Astrocyte Complex D Calvetti, Y Cheng, E Somersalo arXiv preprint arXiv:1412.5693, 2014 | | 2014 |
Erkki SomersaloProfessor of Mathematics, Case Western Reserve University確認したメール アドレス: case.edu