| A microenvironment-induced myeloproliferative syndrome caused by retinoic acid receptor γ deficiency CR Walkley, GH Olsen, S Dworkin, SA Fabb, J Swann, GA McArthur, ... Cell 129 (6), 1097-1110, 2007 | 622 | 2007 |
| Rb regulates interactions between hematopoietic stem cells and their bone marrow microenvironment CR Walkley, JM Shea, NA Sims, LE Purton, SH Orkin Cell 129 (6), 1081-1095, 2007 | 483 | 2007 |
| The Notch ligand, Jagged-1, influences the development of primitive hematopoietic precursor cells B Varnum-Finney, LE Purton, M Yu, C Brashem-Stein, D Flowers, S Staats, ... Blood, The Journal of the American Society of Hematology 91 (11), 4084-4091, 1998 | 461 | 1998 |
| MicroRNA miR-125a controls hematopoietic stem cell number S Guo, J Lu, R Schlanger, H Zhang, JY Wang, MC Fox, LE Purton, ... Proceedings of the National Academy of Sciences 107 (32), 14229-14234, 2010 | 413 | 2010 |
| Limiting factors in murine hematopoietic stem cell assays LE Purton, DT Scadden Cell stem cell 1 (3), 263-270, 2007 | 382 | 2007 |
| Inhibition of endosteal vascular niche remodeling rescues hematopoietic stem cell loss in AML D Duarte, ED Hawkins, O Akinduro, H Ang, K De Filippo, IY Kong, ... Cell stem cell 22 (1), 64-77. e6, 2018 | 313 | 2018 |
| Pharmacologic targeting of a stem/progenitor population in vivo is associated with enhanced bone regeneration in mice S Mukherjee, N Raje, JA Schoonmaker, JC Liu, T Hideshima, MN Wein, ... The Journal of clinical investigation 118 (2), 491-504, 2008 | 293 | 2008 |
| Osteoblastic regulation of B lymphopoiesis is mediated by Gsα-dependent signaling pathways JY Wu, LE Purton, SJ Rodda, M Chen, LS Weinstein, AP McMahon, ... Proceedings of the National Academy of Sciences 105 (44), 16976-16981, 2008 | 254 | 2008 |
| RARγ is critical for maintaining a balance between hematopoietic stem cell self-renewal and differentiation LE Purton, S Dworkin, GH Olsen, CR Walkley, SA Fabb, SJ Collins, ... The Journal of experimental medicine 203 (5), 1283-1293, 2006 | 236 | 2006 |
| T-cell acute leukaemia exhibits dynamic interactions with bone marrow microenvironments ED Hawkins, D Duarte, O Akinduro, RA Khorshed, D Passaro, M Nowicka, ... Nature 538 (7626), 518-522, 2016 | 221 | 2016 |
| Deciphering hematopoietic stem cells in their niches: a critical appraisal of genetic models, lineage tracing, and imaging strategies C Joseph, JM Quach, CR Walkley, SW Lane, CL Celso, LE Purton Cell stem cell 13 (5), 520-533, 2013 | 203 | 2013 |
| All-trans retinoic acid enhances the long-term repopulating activity of cultured hematopoietic stem cells LE Purton, ID Bernstein, SJ Collins Blood, The Journal of the American Society of Hematology 95 (2), 470-477, 2000 | 173 | 2000 |
| Erythropoietin couples erythropoiesis, B-lymphopoiesis, and bone homeostasis within the bone marrow microenvironment S Singbrant, MR Russell, T Jovic, B Liddicoat, DJ Izon, LE Purton, ... Blood, The Journal of the American Society of Hematology 117 (21), 5631-5642, 2011 | 138 | 2011 |
| All-Trans Retinoic Acid Delays the Differentiation of Primitive Hematopoietic Precursors (lin−c-kit+Sca-1+) While Enhancing the Terminal Maturation of … LE Purton, ID Bernstein, SJ Collins Blood, The Journal of the American Society of Hematology 94 (2), 483-495, 1999 | 138 | 1999 |
| Myeloma plasma cells alter the bone marrow microenvironment by stimulating the proliferation of mesenchymal stromal cells JE Noll, SA Williams, CM Tong, H Wang, JM Quach, LE Purton, ... Haematologica 99 (1), 163, 2014 | 130 | 2014 |
| Negative cell-cycle regulators cooperatively control self-renewal and differentiation of haematopoietic stem cells CR Walkley, ML Fero, WM Chien, LE Purton, GA McArthur nature cell biology 7 (2), 172-178, 2005 | 128 | 2005 |
| What is the true nature of the osteoblastic hematopoietic stem cell niche? M Askmyr, NA Sims, TJ Martin, LE Purton Trends in endocrinology & metabolism 20 (6), 303-309, 2009 | 123 | 2009 |
| Generation and Analysis of Siah2 Mutant Mice IJ Frew, VE Hammond, RA Dickins, JMW Quinn, CR Walkley, NA Sims, ... Molecular and cellular biology 23 (24), 9150-9161, 2003 | 123 | 2003 |
| Gsα enhances commitment of mesenchymal progenitors to the osteoblast lineage but restrains osteoblast differentiation in mice JY Wu, P Aarnisalo, M Bastepe, P Sinha, K Fulzele, MK Selig, M Chen, ... The Journal of clinical investigation 121 (9), 3492-3504, 2011 | 117 | 2011 |
| Mutations in the neutral sphingomyelinase gene SMPD3 implicate the ceramide pathway in human leukemias WJ Kim, RA Okimoto, LE Purton, M Goodwin, SM Haserlat, F Dayyani, ... Blood, The Journal of the American Society of Hematology 111 (9), 4716-4722, 2008 | 115 | 2008 |
