| Leishmaniasis treatment—a challenge that remains: a review DO Santos, CER Coutinho, MF Madeira, CG Bottino, RT Vieira, ... Parasitology research 103, 1-10, 2008 | 417 | 2008 |
| Trypanocidal agents with low cytotoxicity to mammalian cell line: a comparison of the theoretical and biological features of lapachone derivatives VF Ferreira, A Jorqueira, AMT Souza, MN da Silva, MCBV de Souza, ... Bioorganic & medicinal chemistry 14 (16), 5459-5466, 2006 | 110 | 2006 |
| Leishmania amazonensis: early proteinase activities during promastigote–amastigote differentiation in vitro CR Alves, S Corte-Real, SC Bourguignon, CS Chaves, EMB Saraiva Experimental parasitology 109 (1), 38-48, 2005 | 85 | 2005 |
| Potency evaluation of antivenoms in Brazil: the national control laboratory experience between 2000 and 2006 HP Araujo, SC Bourguignon, MAA Boller, A Dias, EPR Lucas, IC Santos, ... Toxicon 51 (4), 502-514, 2008 | 73 | 2008 |
| Oxyrane derivative of α-lapachone is potent growth inhibitor of Trypanosoma cruzi epimastigote forms A Jorqueira, RM Gouvêa, VF Ferreira, MN da Silva, MCBV de Souza, ... Parasitology research 99, 429-433, 2006 | 56 | 2006 |
| BJ-48, a novel thrombin-like enzyme from the Bothrops jararacussu venom with high selectivity for Arg over Lys in P1: role of N-glycosylation in thermostability and active site … FP Silva-Junior, HLM Guedes, LC Garvey, AS Aguiar, SC Bourguignon, ... Toxicon 50 (1), 18-31, 2007 | 54 | 2007 |
| Efficacy of 2-hydroxy-3-phenylsulfanylmethyl-[1, 4]-naphthoquinone derivatives against different Trypanosoma cruzi discrete type units: Identification of a promising hit compound LS Lara, CS Moreira, CM Calvet, GC Lechuga, RS Souza, ... European Journal of Medicinal Chemistry 144, 572-581, 2018 | 47 | 2018 |
| Epoxy-α-Lapachone Has In Vitro and In Vivo Anti-Leishmania (Leishmania) amazonensis Effects and Inhibits Serine Proteinase Activity in This Parasite F Souza-Silva, SC Bourguignon, BAS Pereira, LMC Côrtes, ... Antimicrobial Agents and Chemotherapy 59 (4), 1910-1918, 2015 | 45 | 2015 |
| New oxirane derivatives of 1, 4-naphthoquinones and their evaluation against T. cruzi epimastigote forms PF Carneiro, SB do Nascimento, AV Pinto, FR Maria do Carmo, ... Bioorganic & medicinal chemistry 20 (16), 4995-5000, 2012 | 45 | 2012 |
| Trypanosoma cruzi: Insights into naphthoquinone effects on growth and proteinase activity SC Bourguignon, DFB Cavalcanti, AMT de Souza, HC Castro, ... Experimental parasitology 127 (1), 160-166, 2011 | 40 | 2011 |
| Trypanosoma cruzi: in vitro activity of Epoxy-α-Lap, a derivative of α-lapachone, on trypomastigote and amastigote forms SC Bourguignon, HC Castro, DO Santos, CR Alves, VF Ferreira, IL Gama, ... Experimental Parasitology 122 (2), 91-96, 2009 | 37 | 2009 |
| Evidences for leishmanicidal activity of the naphthoquinone derivative epoxy-α-lapachone F Souza-Silva, SB do Nascimento, SC Bourguignon, BAS Pereira, ... Experimental Parasitology 147, 81-84, 2014 | 36 | 2014 |
| Localization of lectin-binding sites on the surface of Trypanosoma cruzi grown in chemically defined conditions SC Bourguignon, W de Souza, T Souto-Padron Histochemistry and Cell Biology 110, 527-534, 1998 | 36 | 1998 |
| Detrimental effect of nitric oxide on Trypanosoma cruzi and Leishmania major like cells SC Bourguignon, CR Alves, S Giovanni-De-Simone Acta tropica 66 (2), 109-118, 1997 | 32 | 1997 |
| Interaction of Mycobacterium leprae with the HaCaT human keratinocyte cell line: new frontiers in the cellular immunology of leprosy ECD Lyrio, IC Campos‐Souza, LCD Corrêa, GC Lechuga, M Verícimo, ... Experimental dermatology 24 (7), 536-542, 2015 | 30 | 2015 |
| Expression of B7‐1 costimulatory molecules in patients with multibacillary leprosy and reactional states DO Santos, HC Castro, SC Bourguignon, OM Bastos, CR Rodrigues, ... Clinical and experimental dermatology 32 (1), 75-80, 2007 | 30 | 2007 |
| The combination therapy of meglumine antimoniate and oxiranes (epoxy-α-lapachone and epoxymethyl-lawsone) enhance the leishmanicidal effect in mice infected by Leishmania … LF Gonçalves-Oliveira, F Souza-Silva, LM de Castro Côrtes, LB Veloso, ... International Journal for Parasitology: Drugs and Drug Resistance 10, 101-108, 2019 | 27 | 2019 |
| Biological aspects of the Trypanosoma cruzi (Dm28c clone) intermediate form, between epimastigote and trypomastigote, obtained in modified liver infusion tryptose (LIT) medium SC Bourguignon, CB Mello, DO Santos, MS Gonzalez, T Souto-Padron Acta tropica 98 (1), 103-109, 2006 | 25 | 2006 |
| Interactions between 4-aminoquinoline and heme: Promising mechanism against Trypanosoma cruzi GC Lechuga, JC Borges, CM Calvet, HP de Araújo, AA Zuma, ... International Journal for Parasitology: Drugs and Drug Resistance 6 (3), 154-164, 2016 | 24 | 2016 |
| Infection of Mouse Dermal Fibroblasts by the Monoxenous Trypanosomatid Protozoa Crithidia deanei and Herpetomonas roitmani DO Santos, SC Bourguignon, HC Castro, JS Silva, LS Franco, ... Journal of Eukaryotic Microbiology 51 (5), 570-574, 2004 | 24 | 2004 |