Nanomaterials for T-cell cancer immunotherapy N Gong, NC Sheppard, MM Billingsley, CH June, MJ Mitchell Nature Nanotechnology 16 (1), 25-36, 2021 | 234 | 2021 |
Polyethyleneimine is a potent mucosal adjuvant for viral glycoprotein antigens F Wegmann, KH Gartlan, AM Harandi, SA Brinckmann, M Coccia, ... Nature biotechnology 30 (9), 883-888, 2012 | 227 | 2012 |
Expression-system-dependent modulation of HIV-1 envelope glycoprotein antigenicity and immunogenicity L Kong, NC Sheppard, GBE Stewart-Jones, CL Robson, H Chen, X Xu, ... Journal of molecular biology 403 (1), 131-147, 2010 | 122 | 2010 |
Genetic engineering of T cells for immunotherapy GI Ellis, NC Sheppard, JL Riley Nature Reviews Genetics 22 (7), 427-447, 2021 | 108 | 2021 |
Orthogonal design of experiments for optimization of lipid nanoparticles for mRNA engineering of CAR T cells MM Billingsley, AG Hamilton, D Mai, SK Patel, KL Swingle, NC Sheppard, ... Nano letters 22 (1), 533-542, 2021 | 106 | 2021 |
HERV-K–specific T cells eliminate diverse HIV-1/2 and SIV primary isolates RB Jones, KE Garrison, S Mujib, V Mihajlovic, N Aidarus, DV Hunter, ... The Journal of clinical investigation 122 (12), 2012 | 104 | 2012 |
EV01: a phase I trial in healthy HIV negative volunteers to evaluate a clade C HIV vaccine, NYVAC-C undertaken by the EuroVacc Consortium PA Bart, R Goodall, T Barber, A Harari, A Guimaraes-Walker, M Khonkarly, ... Vaccine 26 (25), 3153-3161, 2008 | 78 | 2008 |
Polyethyleneimine is a potent systemic adjuvant for glycoprotein antigens NC Sheppard, SA Brinckmann, KH Gartlan, M Puthia, C Svanborg, ... International immunology 26 (10), 531-538, 2014 | 75 | 2014 |
Improved HIV-1 specific T-cell responses by short-interval DNA tattooing as compared to intramuscular immunization in non-human primates BE Verstrepen, AD Bins, CS Rollier, P Mooij, G Koopman, NC Sheppard, ... Vaccine 26 (26), 3346-3351, 2008 | 73 | 2008 |
The TRIM5α genotype of rhesus macaques affects acquisition of simian immunodeficiency virus SIVsmE660 infection after repeated limiting-dose intrarectal challenge MR Reynolds, JB Sacha, AM Weiler, GJ Borchardt, CE Glidden, ... Journal of virology 85 (18), 9637-9640, 2011 | 68 | 2011 |
Vaccination with cancer-and HIV infection-associated endogenous retrotransposable elements is safe and immunogenic JB Sacha, IJ Kim, L Chen, JH Ullah, DA Goodwin, HA Simmons, ... The Journal of Immunology 189 (3), 1467-1479, 2012 | 62 | 2012 |
Comparison of human and rhesus macaque T-cell responses elicited by boosting with NYVAC encoding human immunodeficiency virus type 1 clade C immunogens P Mooij, SS Balla-Jhagjhoorsingh, N Beenhakker, P van Haaften, I Baak, ... Journal of virology 83 (11), 5881-5889, 2009 | 41 | 2009 |
Ionizable lipid nanoparticles with integrated immune checkpoint inhibition for mRNA CAR T cell engineering AG Hamilton, KL Swingle, RA Joseph, D Mai, N Gong, MM Billingsley, ... Advanced Healthcare Materials 12 (30), 2301515, 2023 | 37 | 2023 |
Combined disruption of T cell inflammatory regulators Regnase-1 and Roquin-1 enhances antitumor activity of engineered human T cells D Mai, O Johnson, J Reff, TJ Fan, J Scholler, NC Sheppard, CH June Proceedings of the National Academy of Sciences 120 (12), e2218632120, 2023 | 37 | 2023 |
Responsive biomaterials: optimizing control of cancer immunotherapy L Xue, AS Thatte, D Mai, RM Haley, N Gong, X Han, K Wang, ... Nature Reviews Materials 9 (2), 100-118, 2024 | 33 | 2024 |
Two cases of severe pulmonary toxicity from highly active mesothelin-directed CAR T cells AR Haas, RJ Golden, LA Litzky, B Engels, L Zhao, F Xu, JA Taraszka, ... Molecular Therapy 31 (8), 2309-2325, 2023 | 28 | 2023 |
Antigen presenting cell mimetic lipid nanoparticles for rapid mRNA CAR T cell cancer immunotherapy AE Metzloff, MS Padilla, N Gong, MM Billingsley, X Han, M Merolle, D Mai, ... Advanced Materials, 2313226, 2024 | 22 | 2024 |
Tumor-derived small extracellular vesicles inhibit the efficacy of CAR T cells against solid tumors W Zhong, Z Xiao, Z Qin, J Yang, Y Wen, Z Yu, Y Li, NC Sheppard, ... Cancer research 83 (16), 2790-2806, 2023 | 18 | 2023 |
Human endogenous retrovirus K (HML-2) Gag-and Env-specific T-cell responses are infrequently detected in HIV-1-infected subjects using standard peptide matrix-based screening RB Jones, VM John, DV Hunter, E Martin, S Mujib, V Mihajlovic, ... Clinical and Vaccine Immunology 19 (2), 288-292, 2012 | 15 | 2012 |
Adjuvant Q Sattentau, N Sheppard US Patent App. 12/293,380, 2009 | 15 | 2009 |