The transcription factor Myc controls metabolic reprogramming upon T lymphocyte activation R Wang, CP Dillon, LZ Shi, S Milasta, R Carter, D Finkelstein, ... Immunity 35 (6), 871-882, 2011 | 2210 | 2011 |
HIF1α–dependent glycolytic pathway orchestrates a metabolic checkpoint for the differentiation of TH17 and Treg cells LZ Shi, R Wang, G Huang, P Vogel, G Neale, DR Green, H Chi Journal of experimental medicine 208 (7), 1367-1376, 2011 | 1863 | 2011 |
Regulation and function of mTOR signalling in T cell fate decisions H Chi Nature reviews immunology 12 (5), 325-338, 2012 | 1042 | 2012 |
mTORC1 couples immune signals and metabolic programming to establish Treg-cell function H Zeng, K Yang, C Cloer, G Neale, P Vogel, H Chi Nature 499 (7459), 485-490, 2013 | 806 | 2013 |
Dynamic regulation of pro-and anti-inflammatory cytokines by MAPK phosphatase 1 (MKP-1) in innate immune responses H Chi, SP Barry, RJ Roth, JJ Wu, EA Jones, AM Bennett, RA Flavell Proceedings of the National Academy of Sciences 103 (7), 2274-2279, 2006 | 696 | 2006 |
Metabolic coordination of T cell quiescence and activation NM Chapman, MR Boothby, H Chi Nature reviews immunology 20 (1), 55-70, 2020 | 590 | 2020 |
Helper T cell differentiation J Saravia, NM Chapman, H Chi Cellular & molecular immunology 16 (7), 634-643, 2019 | 468 | 2019 |
Autophagy enforces functional integrity of regulatory T cells by coupling environmental cues and metabolic homeostasis J Wei, L Long, K Yang, C Guy, S Shrestha, Z Chen, C Wu, P Vogel, ... Nature immunology 17 (3), 277-285, 2016 | 436 | 2016 |
Deep multilayer brain proteomics identifies molecular networks in Alzheimer’s disease progression B Bai, X Wang, Y Li, PC Chen, K Yu, KK Dey, JM Yarbro, X Han, BM Lutz, ... Neuron 105 (6), 975-991. e7, 2020 | 432 | 2020 |
Receptor interacting protein kinase 2–mediated mitophagy regulates inflammasome activation during virus infection C Lupfer, PG Thomas, PK Anand, P Vogel, S Milasta, J Martinez, G Huang, ... Nature immunology 14 (5), 480-488, 2013 | 414 | 2013 |
T cell exit from quiescence and differentiation into Th2 cells depend on Raptor-mTORC1-mediated metabolic reprogramming K Yang, S Shrestha, H Zeng, PWF Karmaus, G Neale, P Vogel, ... Immunity 39 (6), 1043-1056, 2013 | 395 | 2013 |
Regulation of JNK and p38 MAPK in the immune system: signal integration, propagation and termination G Huang, LZ Shi, H Chi Cytokine 48 (3), 161-169, 2009 | 386 | 2009 |
The receptor S1P1 overrides regulatory T cell–mediated immune suppression through Akt-mTOR G Liu, S Burns, G Huang, K Boyd, RL Proia, RA Flavell, H Chi Nature immunology 10 (7), 769-777, 2009 | 386 | 2009 |
Treg cells require the phosphatase PTEN to restrain TH1 and TFH cell responses S Shrestha, K Yang, C Guy, P Vogel, G Neale, H Chi Nature immunology 16 (2), 178-187, 2015 | 376 | 2015 |
The S1P1-mTOR axis directs the reciprocal differentiation of TH1 and Treg cells G Liu, K Yang, S Burns, S Shrestha, H Chi Nature immunology 11 (11), 1047-1056, 2010 | 352 | 2010 |
Integrative proteomics and phosphoproteomics profiling reveals dynamic signaling networks and bioenergetics pathways underlying T cell activation H Tan, K Yang, Y Li, TI Shaw, Y Wang, DB Blanco, X Wang, JH Cho, ... Immunity 46 (3), 488-503, 2017 | 346 | 2017 |
The kinase TAK1 integrates antigen and cytokine receptor signaling for T cell development, survival and function YY Wan, H Chi, M Xie, MD Schneider, RA Flavell Nature immunology 7 (8), 851-858, 2006 | 334 | 2006 |
mTORC1 and mTORC2 kinase signaling and glucose metabolism drive follicular helper T cell differentiation HU Zeng, S Cohen, C Guy, S Shrestha, G Neale, SA Brown, C Cloer, ... Immunity 45 (3), 540-554, 2016 | 333 | 2016 |
Targeting REGNASE-1 programs long-lived effector T cells for cancer therapy J Wei, L Long, W Zheng, Y Dhungana, SA Lim, C Guy, Y Wang, YD Wang, ... Nature 576 (7787), 471-476, 2019 | 324 | 2019 |
Costimulation via the tumor-necrosis factor receptor superfamily couples TCR signal strength to the thymic differentiation of regulatory T cells SA Mahmud, LS Manlove, HM Schmitz, Y Xing, Y Wang, DL Owen, ... Nature immunology 15 (5), 473-481, 2014 | 306 | 2014 |