The P450 superfamily: update on new sequences, gene mapping, accession numbers, early trivial names of enzymes, and nomenclature DR Nelson, T Kamataki, DJ Waxman, FP Guengerich, RW Estabrook, ... DNA and cell biology 12 (1), 1-51, 1993 | 2295 | 1993 |
P450 genes: structure, evolution, and regulation DW Nebert, FJ Gonzalez Annual review of biochemistry 56 (1), 945-993, 1987 | 2158 | 1987 |
Peroxisome proliferator–activated receptor α mediates the adaptive response to fasting S Kersten, J Seydoux, JM Peters, FJ Gonzalez, B Desvergne, W Wahli The Journal of clinical investigation 103 (11), 1489-1498, 1999 | 2083 | 1999 |
Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis CJ Sinal, M Tohkin, M Miyata, JM Ward, G Lambert, FJ Gonzalez Cell 102 (6), 731-744, 2000 | 2060 | 2000 |
Targeted disruption of the α isoform of the peroxisome proliferator-activated receptor gene in mice results in abolishment of the pleiotropic effects of peroxisome proliferators SST Lee, T Pineau, J Drago, EJ Lee, JW Owens, DL Kroetz, ... Molecular and cellular biology 15 (6), 3012-3022, 1995 | 1986 | 1995 |
Mitochondrial autophagy is an HIF-1-dependent adaptive metabolic response to hypoxia H Zhang, M Bosch-Marce, LA Shimoda, YS Tan, JH Baek, JB Wesley, ... Journal of Biological Chemistry 283 (16), 10892-10903, 2008 | 1957 | 2008 |
The molecular biology of cytochrome P450s FJ Gonzalez Pharmacol. Rev. 40, 243-288, 1988 | 1920 | 1988 |
The P450 superfamily: updated listing of all genes and recommended nomenclature for the chromosomal loci DW Nebert, DR Nelson, M Adesnik, MJ Coon, RW Estabrook, ... Dna 8 (1), 1-13, 1989 | 1915 | 1989 |
C/EBPα induces adipogenesis through PPARγ: a unified pathway ED Rosen, CH Hsu, X Wang, S Sakai, MW Freeman, FJ Gonzalez, ... Genes & development 16 (1), 22-26, 2002 | 1882 | 2002 |
The PPARα–leukotriene B4 pathway to inflammation control PR Devchand, H Keller, JM Peters, M Vazquez, FJ Gonzalez, W Wahli Nature 384 (6604), 39-43, 1996 | 1797 | 1996 |
The P450 superfamily: update on new sequences, gene mapping, and recommended nomenclature DW NEBERT, DR NELSON, MJ COON, RW ESTABROOK, ... DNA and cell biology 10 (1), 1-14, 1991 | 1436 | 1991 |
Peroxisome proliferator-activated receptor α negatively regulates the vascular inflammatory gene response by negative cross-talk with transcription factors NF-κB and AP-1 P Delerive, K De Bosscher, S Besnard, WV Berghe, JM Peters, ... Journal of Biological Chemistry 274 (45), 32048-32054, 1999 | 1395 | 1999 |
Role of aryl hydrocarbon receptor-mediated induction of the CYP1 enzymes in environmental toxicity and cancer DW Nebert, TP Dalton, AB Okey, FJ Gonzalez Journal of biological chemistry 279 (23), 23847-23850, 2004 | 1378 | 2004 |
Immune system impairment and hepatic fibrosis in mice lacking the dioxin-binding Ah receptor P Fernandez-Salguero, T Pineau, DM Hilbert, T McPhail, SST Lee, ... Science 268 (5211), 722-726, 1995 | 1364 | 1995 |
Hepatocyte nuclear factor 4α (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis GP Hayhurst, YH Lee, G Lambert, JM Ward, FJ Gonzalez Molecular and cellular biology 21 (4), 1393-1403, 2001 | 1337 | 2001 |
The T/ebp null mouse: thyroid-specific enhancer-binding protein is essential for the organogenesis of the thyroid, lung, ventral forebrain, and pituitary. S Kimura, Y Hara, T Pineau, P Fernandez-Salguero, CH Fox, JM Ward, ... Genes & development 10 (1), 60-69, 1996 | 1329 | 1996 |
International Union of Pharmacology. LXI. Peroxisome proliferator-activated receptors L Michalik, J Auwerx, JP Berger, VK Chatterjee, CK Glass, FJ Gonzalez, ... Pharmacological reviews 58 (4), 726-741, 2006 | 1294 | 2006 |
Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice Y Zhang, FY Lee, G Barrera, H Lee, C Vales, FJ Gonzalez, TM Willson, ... Proceedings of the National Academy of Sciences 103 (4), 1006-1011, 2006 | 1102 | 2006 |
Altered constitutive expression of fatty acid-metabolizing enzymes in mice lacking the peroxisome proliferator-activated receptor α (PPARα) T Aoyama, JM Peters, N Iritani, T Nakajima, K Furihata, T Hashimoto, ... Journal of Biological Chemistry 273 (10), 5678-5684, 1998 | 1080 | 1998 |
Aryl-hydrocarbon receptor-deficient mice are resistant to 2, 3, 7, 8-tetrachlorodibenzo-p-dioxin-induced toxicity PM Fernandez-Salguero, DM Hilbert, S Rudikoff, JM Ward, FJ Gonzalez Toxicology and applied pharmacology 140 (1), 173-179, 1996 | 1062 | 1996 |