Mitochondrial dynamics and metabolic regulation T Wai, T Langer Trends in Endocrinology & Metabolism 27 (2), 105-117, 2016 | 1333 | 2016 |
The i-AAA protease YME1L and OMA1 cleave OPA1 to balance mitochondrial fusion and fission R Anand, T Wai, MJ Baker, N Kladt, AC Schauss, E Rugarli, T Langer Journal of Cell Biology 204 (6), 919-929, 2014 | 872 | 2014 |
Distinct fission signatures predict mitochondrial degradation or biogenesis T Kleele, T Rey, J Winter, S Zaganelli, D Mahecic, H Perreten Lambert, ... Nature 593 (7859), 435-439, 2021 | 566 | 2021 |
Imbalanced OPA1 processing and mitochondrial fragmentation cause heart failure in mice T Wai, J García-Prieto, MJ Baker, C Merkwirth, P Benit, P Rustin, ... Science 350 (6265), aad0116, 2015 | 542 | 2015 |
The mitochondrial DNA genetic bottleneck results from replication of a subpopulation of genomes T Wai, D Teoli, EA Shoubridge Nature genetics 40 (12), 1484-1488, 2008 | 522 | 2008 |
The role of mitochondrial DNA copy number in mammalian fertility T Wai, A Ao, X Zhang, D Cyr, D Dufort, EA Shoubridge Biology of reproduction 83 (1), 52-62, 2010 | 485 | 2010 |
Mitochondrial DNA and the mammalian oocyte EA Shoubridge, T Wai Current topics in developmental biology 77, 87-111, 2007 | 342 | 2007 |
Ligand-dependent nuclear receptor corepressor LCoR functions by histone deacetylase-dependent and-independent mechanisms I Fernandes, Y Bastien, T Wai, K Nygard, R Lin, O Cormier, HS Lee, F Eng, ... Molecular cell 11 (1), 139-150, 2003 | 315 | 2003 |
LRPPRC and SLIRP interact in a ribonucleoprotein complex that regulates posttranscriptional gene expression in mitochondria F Sasarman, C Brunel-Guitton, H Antonicka, T Wai, EA Shoubridge, ... Molecular biology of the cell 21 (8), 1315-1323, 2010 | 300 | 2010 |
Quality control of the mitochondrion MYW Ng, T Wai, A Simonsen Developmental cell 56 (7), 881-905, 2021 | 299 | 2021 |
Identification of the gene responsible for the cblB complementation group of vitamin B12-dependent methylmalonic aciduria CM Dobson, T Wai, D Leclerc, H Kadir, M Narang, JP Lerner-Ellis, ... Human molecular genetics 11 (26), 3361-3369, 2002 | 219 | 2002 |
Identification of the gene responsible for the cblA complementation group of vitamin B12-responsive methylmalonic acidemia based on analysis of prokaryotic gene arrangements CM Dobson, T Wai, D Leclerc, A Wilson, X Wu, C Doré, T Hudson, ... Proceedings of the National Academy of Sciences 99 (24), 15554-15559, 2002 | 208 | 2002 |
TRIAP1/PRELI complexes prevent apoptosis by mediating intramitochondrial transport of phosphatidic acid C Potting, T Tatsuta, T König, M Haag, T Wai, MJ Aaltonen, T Langer Cell metabolism 18 (2), 287-295, 2013 | 204 | 2013 |
The membrane scaffold SLP2 anchors a proteolytic hub in mitochondria containing PARL and the i‐AAA protease YME1L T Wai, S Saita, H Nolte, S Müller, T König, R Richter‐Dennerlein, ... EMBO reports 17 (12), 1844-1856, 2016 | 191 | 2016 |
Hyperhomocysteinemia due to methionine synthase deficiency, cblG: structure of the MTR gene, genotype diversity, and recognition of a common mutation, P1173L D Watkins, M Ru, HY Hwang, CD Kim, A Murray, NS Philip, W Kim, ... The American Journal of Human Genetics 71 (1), 143-153, 2002 | 162 | 2002 |
Variation in germline mtDNA heteroplasmy is determined prenatally but modified during subsequent transmission C Freyer, LM Cree, A Mourier, JB Stewart, C Koolmeister, D Milenkovic, ... Nature genetics 44 (11), 1282-1285, 2012 | 145 | 2012 |
Homozygous YME1L1 mutation causes mitochondriopathy with optic atrophy and mitochondrial network fragmentation B Hartmann, T Wai, H Hu, T MacVicar, L Musante, B Fischer-Zirnsak, ... elife 5, e16078, 2016 | 116 | 2016 |
SLIRP regulates the rate of mitochondrial protein synthesis and protects LRPPRC from degradation M Lagouge, A Mourier, HJ Lee, H Spåhr, T Wai, C Kukat, E Silva Ramos, ... PLoS genetics 11 (8), e1005423, 2015 | 113 | 2015 |
Stomatin-Like Protein 2 Is Required for In Vivo Mitochondrial Respiratory Chain Supercomplex Formation and Optimal Cell Function P Mitsopoulos, YH Chang, T Wai, T König, SD Dunn, T Langer, ... Molecular and cellular biology 35 (10), 1838-1847, 2015 | 93 | 2015 |
Mutations in the MMAA gene in patients with the cblA disorder of vitamin B12 metabolism JP Lerner‐Ellis, CM Dobson, T Wai, D Watkins, JC Tirone, D Leclerc, ... Human mutation 24 (6), 509-516, 2004 | 87 | 2004 |