オープン アクセスを義務付けられた論文 - Johnny Habchi詳細
一般には非公開: 2 件
Chemical and mechanistic analysis of photodynamic inhibition of Alzheimer's β-amyloid aggregation
M Ahn, BI Lee, S Chia, J Habchi, JR Kumita, M Vendruscolo, CM Dobson, ...
Chemical Communications 55 (8), 1152-1155, 2019
委任: A*Star, Singapore, UK Biotechnology and Biological Sciences Research Council …
Order and disorder in the replicative complex of paramyxoviruses
J Erales, D Blocquel, J Habchi, M Beltrandi, A Gruet, M Dosnon, C Bignon, ...
Intrinsically Disordered Proteins Studied by NMR Spectroscopy, 351-381, 2015
委任: Government of Italy
一般公開: 32 件
Introducing protein intrinsic disorder
J Habchi, P Tompa, S Longhi, VN Uversky
Chemical reviews 114 (13), 6561-6588, 2014
委任: Research Foundation (Flanders)
Cholesterol catalyses Aβ42 aggregation through a heterogeneous nucleation pathway in the presence of lipid membranes
J Habchi, S Chia, C Galvagnion, TCT Michaels, MMJ Bellaiche, ...
Nature chemistry 10 (6), 673-683, 2018
委任: Swiss National Science Foundation, US National Institutes of Health, Knut …
Systematic development of small molecules to inhibit specific microscopic steps of Aβ42 aggregation in Alzheimer’s disease
J Habchi, S Chia, R Limbocker, B Mannini, M Ahn, M Perni, O Hansson, ...
Proceedings of the National Academy of Sciences 114 (2), E200-E208, 2017
委任: UK Engineering and Physical Sciences Research Council
Chemical kinetics for bridging molecular mechanisms and macroscopic measurements of amyloid fibril formation
TCT Michaels, A Šarić, J Habchi, S Chia, G Meisl, M Vendruscolo, ...
Annual review of physical chemistry 69 (1), 273-298, 2018
委任: Swiss National Science Foundation, UK Biotechnology and Biological Sciences …
Trodusquemine enhances Aβ42 aggregation but suppresses its toxicity by displacing oligomers from cell membranes
R Limbocker, S Chia, FS Ruggeri, M Perni, R Cascella, GT Heller, G Meisl, ...
Nature communications 10 (1), 225, 2019
委任: Swiss National Science Foundation, Bill & Melinda Gates Foundation, UK …
Structural and dynamics analysis of intrinsically disordered proteins by high-speed atomic force microscopy
N Kodera, D Noshiro, SK Dora, T Mori, J Habchi, D Blocquel, A Gruet, ...
Nature Nanotechnology 16 (2), 181-189, 2021
委任: Agence Nationale de la Recherche
Quantifying misfolded protein oligomers as drug targets and biomarkers in Alzheimer and Parkinson diseases
K Kulenkampff, AM Wolf Perez, P Sormanni, J Habchi, M Vendruscolo
Nature Reviews Chemistry 5 (4), 277-294, 2021
委任: UK Medical Research Council, Royal Society UK
Rational design of a conformation-specific antibody for the quantification of Aβ oligomers
FA Aprile, P Sormanni, M Podpolny, S Chhangur, LM Needham, ...
Proceedings of the National Academy of Sciences 117 (24), 13509-13518, 2020
委任: Bill & Melinda Gates Foundation, Alzheimers's UK, UK Biotechnology and …
Structural disorder within paramyxovirus nucleoproteins and phosphoproteins
J Habchi, S Longhi
Molecular Biosystems 8 (1), 69-81, 2012
委任: US National Institutes of Health
SAR by kinetics for drug discovery in protein misfolding diseases
S Chia, J Habchi, TCT Michaels, SIA Cohen, S Linse, CM Dobson, ...
Proceedings of the National Academy of Sciences 115 (41), 10245-10250, 2018
委任: Swiss National Science Foundation, Knut and Alice Wallenberg Foundation …
Infrared nanospectroscopy reveals the molecular interaction fingerprint of an aggregation inhibitor with single Aβ42 oligomers
FS Ruggeri, J Habchi, S Chia, RI Horne, M Vendruscolo, TPJ Knowles
Nature Communications 12 (1), 688, 2021
委任: Swiss National Science Foundation, Wellcome Trust, European Commission
Transthyretin inhibits primary and secondary nucleations of amyloid-β peptide aggregation and reduces the toxicity of its oligomers
SA Ghadami, S Chia, FS Ruggeri, G Meisl, F Bemporad, J Habchi, ...
Biomacromolecules 21 (3), 1112-1125, 2020
委任: Swiss National Science Foundation, Government of Italy
Massively parallel C. elegans tracking provides multi-dimensional fingerprints for phenotypic discovery
M Perni, PK Challa, JB Kirkegaard, R Limbocker, M Koopman, ...
Journal of neuroscience methods 306, 57-67, 2018
委任: UK Biotechnology and Biological Sciences Research Council, UK Engineering …
Monomeric and fibrillar α-synuclein exert opposite effects on the catalytic cycle that promotes the proliferation of Aβ42 aggregates
S Chia, P Flagmeier, J Habchi, V Lattanzi, S Linse, CM Dobson, ...
Proceedings of the National Academy of Sciences 114 (30), 8005-8010, 2017
委任: UK Biotechnology and Biological Sciences Research Council, Wellcome Trust
Trodusquemine displaces protein misfolded oligomers from cell membranes and abrogates their cytotoxicity through a generic mechanism
R Limbocker, B Mannini, FS Ruggeri, R Cascella, CK Xu, M Perni, S Chia, ...
Communications biology 3 (1), 435, 2020
委任: Bill & Melinda Gates Foundation, US Department of Defense, UK Biotechnology …
Stabilization and Characterization of Cytotoxic Aβ40 Oligomers Isolated from an Aggregation Reaction in the Presence of Zinc Ions
B Mannini, J Habchi, S Chia, FS Ruggeri, M Perni, TPJ Knowles, ...
ACS chemical neuroscience 9 (12), 2959-2971, 2018
委任: Swiss National Science Foundation, UK Biotechnology and Biological Sciences …
Microfluidic deposition for resolving single-molecule protein architecture and heterogeneity
FS Ruggeri, J Charmet, T Kartanas, Q Peter, S Chia, J Habchi, ...
Nature communications 9 (1), 1-12, 2018
委任: Swiss National Science Foundation, UK Engineering and Physical Sciences …
Squalamine and its derivatives modulate the aggregation of amyloid-β and α-synuclein and suppress the toxicity of their oligomers
R Limbocker, R Staats, S Chia, FS Ruggeri, B Mannini, CK Xu, M Perni, ...
Frontiers in Neuroscience 15, 680026, 2021
委任: Bill & Melinda Gates Foundation, US Department of Defense, Wellcome Trust …
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