| Mitochondrial function in normal and diabetic β-cells P Maechler, CB Wollheim Nature 414 (6865), 807-812, 2001 | 702 | 2001 |
| Glucose sensitivity and metabolism-secretion coupling studied during two-year continuous culture in INS-1E insulinoma cells A Merglen, S Theander, B Rubi, G Chaffard, CB Wollheim, P Maechler Endocrinology 145 (2), 667-678, 2004 | 678 | 2004 |
| Mitochondrial glutamate acts as a messenger in glucose-induced insulin exocytosis P Maechler, CB Wollheim Nature 402 (6762), 685-689, 1999 | 633 | 1999 |
| Islet β-cell secretion determines glucagon release from neighbouring α-cells H Ishihara, P Maechler, A Gjinovci, PL Herrera, CB Wollheim Nature cell biology 5 (4), 330-335, 2003 | 522 | 2003 |
| Regulation of insulin secretion by SIRT4, a mitochondrial ADP-ribosyltransferase N Ahuja, B Schwer, S Carobbio, D Waltregny, BJ North, V Castronovo, ... Journal of Biological Chemistry 282 (46), 33583-33592, 2007 | 509 | 2007 |
| Preventing mitochondrial fission impairs mitochondrial function and leads to loss of mitochondrial DNA PA Parone, S Da Cruz, D Tondera, Y Mattenberger, DI James, P Maechler, ... PloS one 3 (9), e3257, 2008 | 497 | 2008 |
| Hydrogen peroxide alters mitochondrial activation and insulin secretion in pancreatic beta cells P Maechler, L Jornot, CB Wollheim Journal of Biological Chemistry 274 (39), 27905-27913, 1999 | 447 | 1999 |
| New insights into amino acid metabolism, β-cell function and diabetes P Newsholme, L Brennan, B Rubi, P Maechler Clinical science 108 (3), 185-194, 2005 | 341 | 2005 |
| Mitochondrial dysfunction in pancreatic β cells S Supale, N Li, T Brun, P Maechler Trends in Endocrinology & Metabolism 23 (9), 477-487, 2012 | 309 | 2012 |
| Dopamine D2-like receptors are expressed in pancreatic beta cells and mediate inhibition of insulin secretion B Rubí, S Ljubicic, S Pournourmohammadi, S Carobbio, M Armanet, ... Journal of Biological Chemistry 280 (44), 36824-36832, 2005 | 298 | 2005 |
| Hepatocyte nuclear factor 4α regulates the expression of pancreatic β-cell genes implicated in glucose metabolism and nutrient-induced insulin secretion H Wang, P Maechler, PA Antinozzi, KA Hagenfeldt, CB Wollheim Journal of Biological Chemistry 275 (46), 35953-35959, 2000 | 265 | 2000 |
| Saturated fatty acid‐induced insulin resistance is associated with mitochondrial dysfunction in skeletal muscle cells SM Hirabara, R Curi, P Maechler Journal of cellular physiology 222 (1), 187-194, 2010 | 259 | 2010 |
| Minireview: new roles for peripheral dopamine on metabolic control and tumor growth: let’s seek the balance B Rubí, P Maechler Endocrinology 151 (12), 5570-5581, 2010 | 248 | 2010 |
| Pdx1 level defines pancreatic gene expression pattern and cell lineage differentiation H Wang, P Maechler, B Ritz-Laser, KA Hagenfeldt, H Ishihara, J Philippe, ... Journal of Biological Chemistry 276 (27), 25279-25286, 2001 | 224 | 2001 |
| Mitochondrial activation directly triggers the exocytosis of insulin in permeabilized pancreatic β-cells P Maechler, ED Kennedy, T Pozzan, CB Wollheim The EMBO Journal 16 (13), 3833-3841, 1997 | 220 | 1997 |
| Resveratrol potentiates glucose-stimulated insulin secretion in INS-1E β-cells and human islets through a SIRT1-dependent mechanism L Vetterli, T Brun, L Giovannoni, D Bosco, P Maechler Journal of Biological Chemistry 286 (8), 6049-6060, 2011 | 199 | 2011 |
| Dominant-negative suppression of HNF-1α function results in defective insulin gene transcription and impaired metabolism-secretion coupling in a pancreatic β-cell line H Wang, P Maechler, KA Hagenfeldt, CB Wollheim The EMBO journal 17 (22), 6701-6713, 1998 | 194 | 1998 |
| Effects of depletion of mitochondrial DNA in metabolism secretion coupling in INS-1 cells. ED Kennedy, P Maechler, CB Wollheim Diabetes 47 (3), 374-380, 1998 | 191 | 1998 |
| Mitochondrial signals in glucose‐stimulated insulin secretion in the beta cell P Maechler, CB Wollheim The Journal of physiology 529 (1), 49-56, 2000 | 175 | 2000 |
| In beta-cells, mitochondria integrate and generate metabolic signals controlling insulin secretion P Maechler, S Carobbio, B Rubi The international journal of biochemistry & cell biology 38 (5-6), 696-709, 2006 | 174 | 2006 |