| Trimeric HIV-1-Env structures define glycan shields from clades A, B, and G GBE Stewart-Jones, C Soto, T Lemmin, GY Chuang, A Druz, R Kong, ... Cell 165 (4), 813-826, 2016 | 441 | 2016 |
| Fusion peptide of HIV-1 as a site of vulnerability to neutralizing antibody R Kong, K Xu, T Zhou, P Acharya, T Lemmin, K Liu, G Ozorowski, C Soto, ... Science 352 (6287), 828-833, 2016 | 352 | 2016 |
| Epitope-based vaccine design yields fusion peptide-directed antibodies that neutralize diverse strains of HIV-1 K Xu, P Acharya, R Kong, C Cheng, GY Chuang, K Liu, MK Louder, ... Nature medicine 24 (6), 857-867, 2018 | 293 | 2018 |
| Palmitoylated calnexin is a key component of the ribosome–translocon complex AKK Lakkaraju, L Abrami, T Lemmin, S Blaskovic, B Kunz, A Kihara, ... The EMBO journal 31 (7), 1823-1835, 2012 | 215 | 2012 |
| Structures of HIV-1 Env V1V2 with broadly neutralizing antibodies reveal commonalities that enable vaccine design J Gorman, C Soto, MM Yang, TM Davenport, M Guttman, RT Bailer, ... Nature structural & molecular biology 23 (1), 81-90, 2016 | 196 | 2016 |
| Quantification of the impact of the HIV-1-glycan shield on antibody elicitation T Zhou, NA Doria-Rose, C Cheng, GBE Stewart-Jones, GY Chuang, ... Cell reports 19 (4), 719-732, 2017 | 187 | 2017 |
| Structural heterogeneity and intersubject variability of Aβ in familial and sporadic Alzheimer’s disease C Condello, T Lemmin, J Stöhr, M Nick, Y Wu, AM Maxwell, JC Watts, ... Proceedings of the National Academy of Sciences 115 (4), E782-E791, 2018 | 141 | 2018 |
| Critical roles of isoleucine-364 and adjacent residues in a hydrophobic gate control of phospholipid transport by the mammalian P4-ATPase ATP8A2 AL Vestergaard, JA Coleman, T Lemmin, SA Mikkelsen, LL Molday, ... Proceedings of the National Academy of Sciences 111 (14), E1334-E1343, 2014 | 118 | 2014 |
| De novo design of a hyperstable non-natural protein–ligand complex with sub-Å accuracy NF Polizzi, Y Wu, T Lemmin, AM Maxwell, SQ Zhang, J Rawson, ... Nature chemistry 9 (12), 1157-1164, 2017 | 117 | 2017 |
| Alzheimer’s disease mutations in APP but not γ-secretase modulators affect epsilon-cleavage-dependent AICD production M Dimitrov, JR Alattia, T Lemmin, R Lehal, A Fligier, J Houacine, ... Nature communications 4 (1), 2246, 2013 | 112 | 2013 |
| Structural polymorphism of Alzheimer’s β-amyloid fibrils as controlled by an E22 switch: A solid-state NMR study MR Elkins, T Wang, M Nick, H Jo, T Lemmin, SB Prusiner, WF DeGrado, ... Journal of the American Chemical Society 138 (31), 9840-9852, 2016 | 96 | 2016 |
| RosENet: improving binding affinity prediction by leveraging molecular mechanics energies with an ensemble of 3D convolutional neural networks H Hassan-Harrirou, C Zhang, T Lemmin Journal of chemical information and modeling 60 (6), 2791-2802, 2020 | 94 | 2020 |
| Designed metalloprotein stabilizes a semiquinone radical G Ulas, T Lemmin, Y Wu, GT Gassner, WF DeGrado Nature chemistry 8 (4), 354-359, 2016 | 90 | 2016 |
| A 31-residue peptide induces aggregation of tau's microtubule-binding region in cells J Stöhr, H Wu, M Nick, Y Wu, M Bhate, C Condello, N Johnson, J Rodgers, ... Nature chemistry 9 (9), 874-881, 2017 | 80 | 2017 |
| XFEL structures of the influenza M2 proton channel: Room temperature water networks and insights into proton conduction JL Thomaston, RA Woldeyes, T Nakane, A Yamashita, T Tanaka, ... Proceedings of the National Academy of Sciences 114 (51), 13357-13362, 2017 | 79 | 2017 |
| De novo design of covalently constrained mesosize protein scaffolds with unique tertiary structures B Dang, H Wu, VK Mulligan, M Mravic, Y Wu, T Lemmin, A Ford, DA Silva, ... Proceedings of the National Academy of Sciences 114 (41), 10852-10857, 2017 | 65 | 2017 |
| A coiled coil switch mediates cold sensing by the thermosensory protein DesK E Saita, LA Abriata, YT Tsai, F Trajtenberg, T Lemmin, A Buschiazzo, ... Molecular microbiology 98 (2), 258-271, 2015 | 59 | 2015 |
| Assembly of the Transmembrane Domain of E. coli PhoQ Histidine Kinase: Implications for Signal Transduction from Molecular Simulations T Lemmin, CS Soto, G Clinthorne, WF DeGrado, M Dal Peraro PLoS computational biology 9 (1), e1002878, 2013 | 58 | 2013 |
| Perturbations of the straight transmembrane α-helical structure of the amyloid precursor protein affect its processing by γ-secretase T Lemmin, M Dimitrov, PC Fraering, M Dal Peraro Journal of Biological Chemistry 289 (10), 6763-6774, 2014 | 52 | 2014 |
| Microsecond dynamics and network analysis of the HIV-1 SOSIP Env trimer reveal collective behavior and conserved microdomains of the glycan shield T Lemmin, C Soto, J Stuckey, PD Kwong Structure 25 (10), 1631-1639. e2, 2017 | 50 | 2017 |