The pentose phosphate pathway and cancer KC Patra, N Hay Trends in biochemical sciences 39 (8), 347-354, 2014 | 1481 | 2014 |
Hexokinase 2 is required for tumor initiation and maintenance and its systemic deletion is therapeutic in mouse models of cancer KC Patra, Q Wang, PT Bhaskar, L Miller, Z Wang, W Wheaton, N Chandel, ... Cancer cell 24 (2), 213-228, 2013 | 903 | 2013 |
Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin D DeWaal, V Nogueira, AR Terry, KC Patra, SM Jeon, G Guzman, J Au, ... Nature communications 9 (1), 446, 2018 | 477 | 2018 |
TAS-120 overcomes resistance to ATP-competitive FGFR inhibitors in patients with FGFR2 fusion–positive intrahepatic cholangiocarcinoma L Goyal, L Shi, LY Liu, F Fece de la Cruz, JK Lennerz, S Raghavan, ... Cancer discovery 9 (8), 1064-1079, 2019 | 338 | 2019 |
Mutant GNAS drives pancreatic tumourigenesis by inducing PKA-mediated SIK suppression and reprogramming lipid metabolism KC Patra, Y Kato, Y Mizukami, S Widholz, M Boukhali, I Revenco, ... Nature cell biology 20 (7), 811-822, 2018 | 174 | 2018 |
Diversity of precursor lesions for pancreatic cancer: the genetics and biology of intraductal papillary mucinous neoplasm KC Patra, N Bardeesy, Y Mizukami Clinical and translational gastroenterology 8 (4), e86, 2017 | 131 | 2017 |
Microbial transformation of tannin-rich substrate to gallic acid through co-culture method R Banerjee, G Mukherjee, KC Patra Bioresource Technology 96 (8), 949-953, 2005 | 113 | 2005 |
Kras and Tp53 mutations cause cholangiocyte-and hepatocyte-derived cholangiocarcinoma MA Hill, WB Alexander, B Guo, Y Kato, K Patra, MR O'Dell, MN McCall, ... Cancer research 78 (16), 4445-4451, 2018 | 108 | 2018 |
mTORC1 hyperactivity inhibits serum deprivation-induced apoptosis via increased hexokinase II and GLUT1 expression, sustained Mcl-1 expression, and glycogen synthase kinase 3β … PT Bhaskar, V Nogueira, KC Patra, SM Jeon, Y Park, RB Robey, N Hay Molecular and cellular biology 29 (18), 5136-5147, 2009 | 65 | 2009 |
DDB2 suppresses epithelial-to-mesenchymal transition in colon cancer N Roy, PV Bommi, UG Bhat, S Bhattacharjee, I Elangovan, J Li, KC Patra, ... Cancer research 73 (12), 3771-3782, 2013 | 63 | 2013 |
A non-catalytic scaffolding activity of hexokinase 2 contributes to EMT and metastasis CS Blaha, G Ramakrishnan, SM Jeon, V Nogueira, H Rho, S Kang, ... Nature Communications 13 (1), 899, 2022 | 59 | 2022 |
Hexokinase 2 as oncotarget KC Patra, N Hay Oncotarget 4 (11), 1862, 2013 | 57 | 2013 |
Selective eradication of cancer displaying hyperactive Akt by exploiting the metabolic consequences of Akt activation V Nogueira, KC Patra, N Hay Elife 7, e32213, 2018 | 47 | 2018 |
REDD1 loss reprograms lipid metabolism to drive progression of RAS mutant tumors S Qiao, SB Koh, V Vivekanandan, D Salunke, KC Patra, E Zaganjor, ... Genes & development 34 (11-12), 751-766, 2020 | 42 | 2020 |
Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms GKL Chan, S Maisel, YC Hwang, BC Pascual, RRB Wolber, P Vu, ... Elife 12, e69521, 2023 | 23 | 2023 |
AMPK-mediated lysosome biogenesis in lung cancer growth KC Patra, VK Weerasekara, N Bardeesy Cell metabolism 29 (2), 238-240, 2019 | 17 | 2019 |
Author Correction: Hexokinase-2 depletion inhibits glycolysis and induces oxidative phosphorylation in hepatocellular carcinoma and sensitizes to metformin D DeWaal, V Nogueira, AR Terry, KC Patra, SM Jeon, G Guzman, J Au, ... Nature Communications 9, 2539, 2018 | 16 | 2018 |
Systemic Akt1 deletion after tumor onset in p53−/− mice increases lifespan and regresses thymic lymphoma emulating p53 restoration WN Yu, V Nogueira, A Sobhakumari, KC Patra, PT Bhaskar, N Hay Cell reports 12 (4), 610-621, 2015 | 11 | 2015 |
EGFR pathway links amino acid levels and induction of macropinocytosis VK Weerasekara, KC Patra, N Bardeesy Developmental Cell 50 (3), 261-263, 2019 | 9 | 2019 |
A cell size theory of aging KC Patra, N Bardeesy Developmental Cell 45 (6), 665-666, 2018 | 5 | 2018 |