| Macrophage-derived Wnt opposes Notch signaling to specify hepatic progenitor cell fate in chronic liver disease L Boulter, O Govaere, TG Bird, S Radulescu, P Ramachandran, ... Nature medicine 18 (4), 572-579, 2012 | 813 | 2012 |
| Genomic and genetic characterization of cholangiocarcinoma identifies therapeutic targets for tyrosine kinase inhibitors JB Andersen, B Spee, BR Blechacz, I Avital, M Komuta, A Barbour, ... Gastroenterology 142 (4), 1021-1031. e15, 2012 | 596 | 2012 |
| Clinicopathological study on cholangiolocellular carcinoma suggesting hepatic progenitor cell origin M Komuta, B Spee, S Vander Borght, R De Vos, C Verslype, R Aerts, ... Hepatology 47 (5), 1544-1556, 2008 | 445 | 2008 |
| Development and evaluation of canine reference genes for accurate quantification of gene expression B Brinkhof, B Spee, J Rothuizen, LC Penning Analytical biochemistry 356 (1), 36-43, 2006 | 298 | 2006 |
| Keratin 19: a key role player in the invasion of human hepatocellular carcinomas O Govaere, M Komuta, J Berkers, B Spee, C Janssen, F De Luca, ... Gut 63 (4), 674-685, 2014 | 282 | 2014 |
| Characterisation of the liver progenitor cell niche in liver diseases: potential involvement of Wnt and Notch signalling B Spee, G Carpino, BA Schotanus, A Katoonizadeh, S Vander Borght, ... Gut 59 (2), 247-257, 2010 | 246 | 2010 |
| Building consensus on definition and nomenclature of hepatic, pancreatic, and biliary organoids A Marsee, FJM Roos, MMA Verstegen, F Roos, M Verstegen, H Clevers, ... Cell stem cell 28 (5), 816-832, 2021 | 215 | 2021 |
| Volumetric bioprinting of organoids and optically tuned hydrogels to build liver‐like metabolic biofactories PN Bernal, M Bouwmeester, J Madrid‐Wolff, M Falandt, S Florczak, ... Advanced Materials 34 (15), 2110054, 2022 | 195 | 2022 |
| Disease modeling and gene therapy of copper storage disease in canine hepatic organoids S Nantasanti, B Spee, HS Kruitwagen, C Chen, N Geijsen, LA Oosterhoff, ... Stem cell reports 5 (5), 895-907, 2015 | 126 | 2015 |
| A chemically defined hydrogel for human liver organoid culture S Ye, JWB Boeter, M Mihajlovic, FG van Steenbeek, ME van Wolferen, ... Advanced functional materials 30 (48), 2000893, 2020 | 124 | 2020 |
| Large‐scale production of LGR5‐positive bipotential human liver stem cells K Schneeberger, N Sánchez‐Romero, S Ye, FG Van Steenbeek, ... Hepatology 72 (1), 257-270, 2020 | 121 | 2020 |
| Long-term adult feline liver organoid cultures for disease modeling of hepatic steatosis HS Kruitwagen, LA Oosterhoff, IGWH Vernooij, IM Schrall, ... Stem Cell Reports 8 (4), 822-830, 2017 | 115 | 2017 |
| Intestinal failure and aberrant lipid metabolism in patients with DGAT1 deficiency JM van Rijn, RC Ardy, Z Kuloğlu, B Härter, DY van Haaften-Visser, ... Gastroenterology 155 (1), 130-143. e15, 2018 | 108 | 2018 |
| Hydrogels for liver tissue engineering S Ye, JWB Boeter, LC Penning, B Spee, K Schneeberger Bioengineering 6 (3), 59, 2019 | 103 | 2019 |
| Biotechnology challenges to in vitro maturation of hepatic stem cells C Chen, A Soto-Gutierrez, PM Baptista, B Spee Gastroenterology 154 (5), 1258-1272, 2018 | 97 | 2018 |
| Converging biofabrication and organoid technologies: the next frontier in hepatic and intestinal tissue engineering? K Schneeberger, B Spee, P Costa, N Sachs, H Clevers, J Malda Biofabrication 9 (1), 013001, 2017 | 97 | 2017 |
| Copper metabolism and oxidative stress in chronic inflammatory and cholestatic liver diseases in dogs B Spee, B Arends, TS van den Ingh, LC Penning, J Rothuizen Journal of veterinary internal medicine 20 (5), 1085-1092, 2006 | 96 | 2006 |
| The Menkes and Wilson disease genes counteract in copper toxicosis in Labrador retrievers: a new canine model for copper-metabolism disorders H Fieten, Y Gill, AJ Martin, M Concilli, K Dirksen, FG van Steenbeek, ... Disease models & mechanisms 9 (1), 25-38, 2016 | 86 | 2016 |
| A GeNorm algorithm-based selection of reference genes for quantitative real-time PCR in skin biopsies of healthy dogs and dogs with atopic dermatitis YM Schlotter, EZ Veenhof, B Brinkhof, VPMG Rutten, B Spee, T Willemse, ... Veterinary Immunology and Immunopathology 129 (1-2), 115-118, 2009 | 86 | 2009 |
| A versatile biosynthetic hydrogel platform for engineering of tissue analogues BJ Klotz, LA Oosterhoff, L Utomo, KS Lim, Q Vallmajo‐Martin, H Clevers, ... Advanced healthcare materials 8 (19), 1900979, 2019 | 85 | 2019 |
